Impairment of myocardial perfusion in both culprit and nonculprit arteries in acute myocardial infarction: A LIMIT AMI substudy

American Journal of Cardiology

Volumn 91, Issue 3, 2003, Pages 325-328

  Murphy, Sabina A ^a,b,c,d,e   Chen, Christopher ^a,b,c,d,e   Gourlay, Steven G ^a,b,c,d,e   Gibbons, Raymond J ^a,b,c,d,e   Barron, Hal V ^a,b,c,d,e   Gibson, C Michael ^a,b,c,d,e  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MAYO CLINIC   (United States)

^e GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; BETA2 INTEGRIN ADHESION RECEPTOR; CD18 ANTIGEN; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MONOCLONAL ANTIBODY; RECEPTOR; RECOMBINANT ANTIBODY; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANGIOGRAPHY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY; DATA ANALYSIS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ELECTROCARDIOGRAM; EPICARDIUM; HEART BLOOD VESSEL; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE PERFUSION; HEART REINFARCTION; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ST SEGMENT ELEVATION; THORAX PAIN;

EID: 0037307821     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(02)03160-0     Document Type: Article

References (11)

1. Gibson C.M., Ryan K.A., Murphy S.A., Rizzo M.J., Kelley M.B., Mesley R., Marble S.J., Giugliano R.P., Dodge J.T., Cannon C.P., Antman E.M. Impaired coronary blood flow in non-culprit arteries in the setting of acute myocardial infarction. J Am Coll Cardiol. 34:1999;974-982.
2. Baran K.W., Nguyen M., McKendall G.R., Lambrew C.T., Dykstra G., Palmeri S.T., Gibbons R.J., Borzak S., Sobel B.E., Gourlay S.G., et al. A double-blind, randomized trial of an anti-CD18 antibody in conjunction with rtPA for acute myocardial infarction the LIMIT AMI Study. Circulation. 104:2001;2778-2783.
3. The Thrombolysis In Myocardial Infarction (TIMI) trial. N Engl J Med. 31:1985;932-936.
4. Gibson C.M., Cannon C.P., Murphy S.A., Ryan K.A., Mesley R., Marble S.J., McCabe C.H., Van de Werf F., Braunwald E. The relationship of the TIMI myocardial perfusion grade to mortality following thrombolytic administration. Circulation. 101:2000;125-130.
5. Gibson C.M., Cannon C.P., Daley W.L., Dodge J.T., Alexander B., Marble S.J., McCabe C.H., Raymond L., Fortin T., Poole W.K., Braunwald E. The TIMI frame count a quantitative method of assessing coronary artery flow. Circulation. 93:1996;879-888.
6. Gibson C.M., Cannon C.P., Murphy S.A., Marble S.J., Barron H.V., Braunwald E. Relationship of the TIMI myocardial perfusion grades, flow grades, frame count and percutaneous coronary intervention to long-term outcomes after thrombolytic administration in acute myocardial infarction. Circulation. 105:2002;1909-1913.
7. Gregorini L., Marco J., Kozakova M., Palombo C., Anguissola G.B., Marco I., Bernies M., Cassagneau B., Disante A., Bossi I., Fajadet J., Heush G. Alpha-adrenergic blockade improves recovery of myocardial perfusion and function after coronary stenting in patients with acute myocardial infarction. Circulation. 99:1999;482-490.
8. Gregorini L., Marco J., Palombo C., Kozakova M., Anguissola G.B., Cassagneau B., Disante A., Bossi I., Fajadet J., Zanchetti A. Post ischemic left ventricular dysfunction is abolished by alpha-adrenergic blockers. J Am Coll Cardiol. 31:1998;992-1001.
9. Gregorini L., Fajadet J., Robert G., Cassagneau B., Bernis M., Marco J. Coronary vasoconstriction after percutaneous transluminal coronary angioplasty is attenuated by anti-adrenergic agents. Circulation. 90:1994;895-907.
10. Heusch G., Deussen A., Thamer V. Cardiac sympathetic nerve activity and progressive vasoconstriction distal to coronary stenoses feed-back aggravation on myocardial ischemia. J Auton Nerv Syst. 13:1985;311-326.
11. Gibson C.M., Luu L., Kermgard S.R., Hynes C., Otten M., Lim J., Appleby M., Michaels A., Marble S.J., Murphy S.A., Barron H.V. Validation of myocardial perfusion grades using digital subtraction angiography (DSA) (abstr). J Am Coll Cardiol. 37:2001;333A.