Empirical models and Hill coefficients [3]

Trends in Pharmacological Sciences

Volumn 24, Issue 2, 2003, Pages 63-65

  Giraldo, Jesús ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; ION CHANNEL; LIGAND; NORADRENALIN;

AGONIST; AORTA; COMPARATIVE STUDY; CONCENTRATION RESPONSE; DRUG EFFECT; EMPIRICISM; LETTER; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NONHUMAN; PARAMETER; PRIORITY JOURNAL; RAT STRAIN; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; VAS DEFERENS;

MODELS, CHEMICAL;

EID: 0037304626     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(02)00048-2     Document Type: Letter

References (6)

1. Hill A.V. The combinations of haemoglobin with oxygen and with carbon monoxide. Biochem. J. 7:1913;471-480.
2. Colquhoun D. The individual effective dose, direct assays, all-or-nothing responses, and the probit transformation. Colquhoun D. Lectures on Biostatistics. 1971;344-364 Oxford University Press.
3. Barlow R., Blake J.F. Hill coefficients and the logistic equation. Trends Pharmacol. Sci. 10:1989;440-441.
4. Giraldo J., et al. Assesing the (a)symmetry of concentration-effect curves: empirical versus mechanistic models. Pharmacol. Ther. 95:2002;21-45.
5. Van Der Graaf P.H., Schoemaker R.C. Analysis of asymmetry of agonist concentration-effect curves. J. Pharmacol. Toxicol. Methods. 41:1999;107-115.
6. Wells J.W. Analysis and interpretation of binding at equilibrium. Hulme C.E. Receptor-ligand Interactions. A Practical Approach. 1992;289-395 Oxford University Press.