High-resolution genomic profiling of occult micrometastatic tumor cells

Genes Chromosomes and Cancer

Volumn 36, Issue 2, 2003, Pages 159-166

  Kraus, Jürgen ^a,b   Pantel, Klaus ^c   Pinkel, Daniel ^d,e   Albertson, Donna G ^d,e,f   Speicher, Michael R ^a,b  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BONE MARROW CELL; CANCER MORTALITY; CHROMOSOME 13Q; CHROMOSOME 18Q; CHROMOSOME 20; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME 9Q; CHROMOSOME LOSS; COMPARATIVE GENOMIC HYBRIDIZATION; DECISION MAKING; DNA FINGERPRINTING; DNA MICROARRAY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE STRUCTURE; GENETIC ANALYSIS; HUMAN; METASTASIS; MICROSCOPIC ANATOMY; MOLECULAR EVOLUTION; OCCULT CANCER; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROGNOSIS; X CHROMOSOME;

BONE MARROW CELLS; BONE MARROW NEOPLASMS; CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; CHROMOSOME PAINTING; CYTOGENETIC ANALYSIS; DISEASE PROGRESSION; GENE AMPLIFICATION; GENE DOSAGE; HUMANS; KARYOTYPING; MALE; NUCLEIC ACID HYBRIDIZATION; PROSTATIC NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0037301144     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.10160     Document Type: Article

References (30)

1. Braun S, Pantel K, Müller P, Janni W, Hepp F, Kentenich CR, Gastroph S, Wischnik A, Dimpfl T, Kindermann G, Riethmüller G, Schlimok G. 2000. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. N Engl J Med 342:525-533.
2. Cher ML, MacGrogan D, Bookstein R, Brown JA, Jenkins RB, Jensen RH. 1994. Comparative genomic hybridization, allelic imbalance, and fluorescence in situ hybridization on chromosome 8 in prostate cancer. Genes Chromosomes Cancer 11:153-162.
3. Cher ML, Bova GS, Moore DH, Small EJ, Carroll PR, Pin SS, Epstein JI, Isaacs WB, Jensen RH. 1996. Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping. Cancer Res 56:3091-3102.
4. Eils R, Uhrig S, Saracoglu K, Sätzler K, Bolzer A, Chassery JM, Petersen I, Ganser M, Speicher MR. 1998. An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH). Cytogenet Cell Genet 82:160-171.
5. El Gedaily A, Bubendorf L, Willi N, Fu W, Richter J, Moch H, Mihatsch MJ, Sauter G, Gasser TC. 2001. Discovery of new DNA amplification loci in prostate cancer by comparative genomic hybridization. Prostate 46:184-190.
6. Fauth C, Speicher MR. 2001. Classifying by colors: FISH-based genome analysis. Cytogenet Cell Genet 93:1-10.
7. Jain AN, Tokuyasu TA, Snijders AM, Segraves R, Albertson DG, Pinkel D. 2002. Fully automatic quantification of microarray image data. Genome Res 12:325-332.
8. Joos S, Bergerheim US, Pan Y, Matsuyama H, Bentz M, du Manoir S, Lichter P. 1995. Mapping of chromosomal gains and losses in prostate cancer by comparative genomic hybridization. Genes Chromosomes Cancer 14:267-276.
9. Klein CA, Schmidt-Kittler O, Schardt JA, Pantel K, Speicher MR, Riethmüller G. 1999. Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. Proc Natl Acad Si USA 96:4494-4499.
10. Lindemann F, Schlimok G, Dirschedl P, Witte J, Riethmüller G. 1992. Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients. Lancet 340:685-689.
11. Mansi JL, Gogas H, Bliss JM, Gazet JC, Berger U, Coombes RC. 1999. Outcome of primary-breast-cancer patients with micrometastases: a long-term follow-up study. Lancet 354:197-202.
12. Müller P, Weckermann D, Riethmüller G, Schlimok G. 1996. Detection of genetic alterations in micrometastatic cells in bone marrow of cancer patients by fluorescence in situ hybridization. Cancer Genet Cytogenet 88:8-16.
13. Pantel K, Otte M. 2001. Occult micrometastasis: enrichment, identification and characterization of single disseminated tumour cells. Semin Cancer Biol 11:327-337.
14. Pantel K, von Knebel-Docberitz M. 2000. Detection and clinical relevance of micrometastatic cancer cells. Curr Opin Oncol 12:95-101.
15. Pantel K, Dickmanns A, Zippelius A, Klein C, Shi J, Hoechtlen-Vollmar W, Schlimok G, Weckermann D, Oberneder R, Fanning E, Riethmüller G. 1995. Establishment of carcinoma cell lines from bone marrow of patients with minimal residual cancer: a novel source of tumor cell vaccines. J Natl Cancer Inst 87:1160-1168.
16. Pantel K, Izbicki J, Passlick B, Angstwurm M, Haussinger K, Thetter O, Riethmüller G. 1996. Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet 347:649-653.
17. Pantel K, Cote RJ, Fodstad O. 1999. Detection and clinical importance of micrometastatic disease. J Natl Cancer Inst 91:1113-1124.
18. Pinkel D, Segraves R, Sudar D, Clark S, Poole I, Kowbel D, Collins C, Kuo WL, Chen C, Zhai Y, Dairkee SH, Ljung BM, Gray JW, Albertson DG. 1998. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet 20:207-211.
19. Pollack JR, Perou CM, Alizadeh AA, Eisen MB, Pergamenschikov A, Williams CF, Jeffrey SS, Botstein D, Brown PO. 1999. Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nat Genet 23:41-46.
20. Putz E, Witter K, Offner S, Stosiek P, Zippelius A, Johnson J, Zahn R, Riethmüller G, Pantel K. 1999. Phenotypic characteristics of cell lines derived from disseminated cancer cells in bone marrow of patients with solid epithelial tumors: establishment of working models for human micrometastases. Cancer Res 59:241-248.
21. Rokman A, Koivisto PA, Matikainen MP, Kuukasjarvi T, Poutiainen M, Helin HJ, Karhu R, Kallioniemi OP, Schleutker J. 2001. Genetic changes in familial prostate cancer by comparative genomic hybridization. Prostate 46:233-239.
22. Snijders AM, Nowak N, Segraves R, Blackwood S, Brown N, Conroy J, Hamilton G, Hindle AK, Huey B, Kimura K, Law S, Myambo K, Palmer J, Ylstra B, Yue JP, Gray JW, Jain AN, Pinkel D, Albertson DG. 2001. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet 29:263-264.
23. Solakoglu O, Maierhofer C, Lahr G, Breit E, Scheunemann P, Heumos I, Pichlmeier U, Schlimok G, Oberneder R, Köllermann MW, Köllermann J, Speicher MR, Pantel K. 2002. Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors. Proc Natl Acad Sci USA 99:2246-2251.
24. Solinas-Toldo S, Lampel S, Stilgenbauer S, Nickolenko J, Benner A, Döhner H, Cremer T, Lichter P. 1997. Matrix-based comparative genomic hybridization: biochips to screen for genomic imbalances. Genes Chromosomes Cancer 20:399-407.
25. Speicher MR, du Manoir S, Schröck E, Holtgreve H, Schoell B, Lengauer C, Cremer T, Ried T. 1993. Molecular cytogenetic analysis of archived, paraffin embedded solid tumors by comparative genomic hybridization after universal PCR. Hum Mol Genet 2:1907-1914.
26. Speicher MR, Ballard SG, Ward DC. 1996. Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nat Genet 12:386-375.
27. Visakorpi T, Kallioniemi AH, Syvanen AC, Hyytinen ER, Karhu R, Tammela T, Isola JJ, Kallioniemi OP. 1995. Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization. Cancer Res 55:342-347.
28. Weckermann D, Müller P, Wawroschek F, Harzmann R, Riethmüller G, Schlimok G. 2001. Disseminated cytokeratin positive tumor cells in the bone marrow of patients with prostate cancer: detection and prognostic value. J Urol 166:699-703.
29. Zitzelsberger H, Kulka U, Lehmann L, Walch A, Smida J, Aubele M, Lorch T, Hofler H, Bauchinger M, Werner M. 1998. Genetic heterogeneity in a prostatic carcinoma and associated prostatic intraepithelial neoplasia as demonstrated by combined use of laser-microdissection, degenerate oligonucleotide primed PCR and comparative genomic hybridization. Virchows Arch 433:297-304.
30. Zitzelsberger H, Engert D, Walch A, Kulka U, Aubele M, Hofler H, Bauchinger M, Werner M. 2001. Chromosomal changes during development and progression of prostate adenocarcinomas. Br J Cancer 84:202-208.