Mathematical modelling of drug transport in tumour multicell spheroids and monolayer cultures

Mathematical Biosciences

Volumn 181, Issue 2, 2003, Pages 177-207

  Ward, John P ^a,b   King, John R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b LOUGHBOROUGH UNIVERSITY   (United Kingdom)

Author keywords

Chemotherapy; Drug transport; Mathematical modelling; Monolayer cultures; Multicell spheroids; Numerical solution

Indexed keywords

CELLS; DIFFUSION; DRUG INFUSION; MATHEMATICAL MODELS; PARTIAL DIFFERENTIAL EQUATIONS; TUMORS;

DRUG TRANSPORT;

DRUG DOSAGE;

CHEMOTHERAPY; MATHEMATICAL ANALYSIS;

ARTICLE; CELL DEATH; CELL SURVIVAL; CONCENTRATION (PARAMETERS); DRUG TRANSPORT; MATHEMATICAL ANALYSIS; MICHAELIS MENTEN KINETICS; MONOLAYER CULTURE; STEADY STATE; TUMOR CELL CULTURE; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DEATH; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; HUMANS; MITOMYCIN; MODELS, BIOLOGICAL; NECROSIS; NEOPLASMS; NUMERICAL ANALYSIS, COMPUTER-ASSISTED; SPHEROIDS, CELLULAR;

EID: 0037299744     PISSN: 00255564     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0025-5564(02)00148-7     Document Type: Article

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