A recombinant human G-CSF/GM-CSF fusion protein from E. coli showing colony stimulating activity on human bone marrow cells

Biotechnology Letters

Volumn 25, Issue 3, 2003, Pages 205-211

  Lee, Ah Young ^a   Chung, Hye Kyung ^a   Bae, Eun Kyong ^a   Hwang, Jung Suk ^a   Sung, Bong Whan ^a   Cho, Chung Won ^a   Kim, Jin Kyoo ^b   Lee, Kyung ^b   Han, Jae Yong ^c   Lee, Choon Taek ^c   Youn, Hyun Joo ^a  

^a Inje University   (South Korea)

^b Changwon National University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

CSF; Cytokine; G CSF GM CSF fusion protein; Recombinant protein

Indexed keywords

HYBRID PROTEIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ARTICLE; BIOSYNTHESIS; BONE MARROW CELL; CELL DIVISION; CHEMISTRY; DRUG EFFECT; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

BASE SEQUENCE; BONE MARROW CELLS; CELL DIVISION; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANULOCYTE COLONY STIMULATING FACTOR, RECOMBINANT; GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTORS, RECOMBINANT; HUMANS; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037296093     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022346800375     Document Type: Article

References (21)

1. Aglietta M, Montemurro F, Fagioli F, Volta C, Botto B, Cantonetti M, Racanelli V, Teofili L, Ferrara R, Amadori S, Castoldi GL, Dammacco F, Levis A (2000) Short term treatment with Escheria coli recombinant human granulocyte-macrophage-colony stimulating factor prior to chemotherapy for Hodgkin disease. Cancer 88: 454-460.
2. Arai K, Lee F, Miyajima A, Miyatake S, Arai N, Yokota T (1990) Cytokines: coordinators of immune and inflammatory response. Annu. Rev. Biochem. 59: 783-836.
3. Bashey A, Corringham S, Gilpin E, Fields KK, Smilee DeFrancisco C, Santos-Ada O, Holman P, Carrier E, Ho AD, Lane TA, Ball ED, Janssen WE, Law P (2000) Simultaneous administration of G-CSF and GM-CSF for re-mobilization in patients with inadequate initial progenitor cell collections for autologous transplantation. Cytotherapy 2: 195-200.
4. Bischof RJ, Zafiropoulos D, Hamilton JA, Campbell IK (2000) Exacerbation of acute inflammatory arthritis by the colony-stimulating factors CSF-1 and granulocyte macrophage (GM)-CSF: evidence of macrophage infiltration and local proliferation. Clin. Exp. Immunol. 119: 361-367.
5. Bollag DM, Rozycki MD, Edelstein SJ (1996) Protein Methods, 2nd edn. New York: Wiley-Liss, Inc.
6. Carter BZ, Milella M, Altieri DC, Andreeff M (2001) Cytokine-regulated expression of survivin in myeloid leukemia. Blood 97: 2784-2790.
7. Garland J (1987) Assays for interleukin-3 and other myeloid colony-stimulating factors. In: Clemens MJ, Morris AG, Gearing AJH, eds. Lymphokines and Interferons: A Practical Approach. Oxford: IRL Press, pp. 303-322.
8. Horton RM, Cai ZL, Ho SN, Pease LR (1990) Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. Biotechniques 8: 528-535.
9. Janik JE, Miller LL, Kopp WC, Taub DD, Dawson H, Stevens D, Kostboth P, Curti BD, Conlon KC, Dunn BK, Donegan SE, Ullrich R, Alvord WG, Gause BL, Longo DL (1999) Treatment with tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients. Clin. Immunol. 93: 209-221.
10. Jarmin DI, Nibbs RJ, Jamieson T, de Bono JS, Graham GJ (1999) Granulocyte macrophage colony-stimulating factor and interleukin-3 regulate chemokine and chemokine receptor expression in bone marrow macrophages. Exp. Hematol. 27: 1735-1745.
11. Kim JK, Tsen MF, Ghetie V, Ward ES (1994) Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis. Eur. J. Immunol. 24: 542-547.
12. McClay EF (2002) Adjuvant therapy for patients with high-risk malignant melanoma. Semin. Oncol. 29: 389-399.
13. Olafsena T, Rasmussena IB, Norderhaugb L, Bruland S, Sandliea I (1998) IgM secretory tailpiece drives multimerisation of bivalent scFv fragments in eukaryotic cells. Immunotechnology 4: 141-153.
14. Petit I, Szyper-Kravitz M, Nagler A, Lahav M, Peled A, Habler L, Ponomaryov T, Taichman RS, Arenzana-Seisdedos F, Fujii N, Sandbank J, Zipori D, Lapidot T (2002) G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat. Immunol. 3: 687-694.
15. Staynov DZ, Cousins DJ, Lee TH (1995) A regulatory element in the promoter of the human granulocyte-macrophage colony stimulating factor gene that has related sequences in other T-cell expressed cytokine genes. Proc. Natl. Acad. Sci. 92: 3606-3610.
16. Sylvester RK (2002) Clinical applications of colony-stimulating factors: a historical perspective. Am. J. Health Syst. Pharm. 59: S6-S12.
17. Todorovska A, Roovers RC, Dolezal O, Kortt AA, Hoogenboom HR, Hudson PJ (2001) Design and application of diabodies, triabodies and tetrabodies for cancer targeting. J. Immunol. Meth. 248: 47-66.
18. Walter MR, Cook WJ, Ealick SE, Nagabhushan TL, Trotta PP, Bugg CE (1992) Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor. J. Mol. Biol. 224: 1075-1085.
19. Wang SY, Hsu ML, Huang MZ, Hsu HC, Tzeng CH, Hung JH, Ho CK (2001) The activity in ex vivo expansion of cord blood myeloid progenitor cells before and after cryopreservation. Acta Haematol. 105: 38-44.
20. Wislez M, Fleury-Feith J, Rabbe N, Moreau J, Cesari D, Milleron B, Mayaud C, Antoine M, Soler P, Cadranel J (2001) Tumor-derived granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor prolong the survival of neutrophils infiltrating bronchoalveolar subtype pulmonary adenocarcinoma. Am. J. Pathol. 159: 1423-1433.
21. Zink T, Ross A, Luers K, Cieslar C, Rudolph R, Holak TA (1994) Structure and dynamics of the human granulocyte colony-stimulating factor determined by NMR spectroscopy: loop mobility in a four-helix-bundle protein. Biochemistry 33: 8453-8463.