메뉴 건너뛰기




Volumn 109, Issue 2, 2003, Pages 175-181

Adrenomedullin and adrenomedullin binding protein-1: Their role in the septic response

Author keywords

Cecal ligation and puncture; Hyperdynamic sepsis; Hypodynamic sepsis; Multiple organ failure; Vascular reactivity; Vasoactive peptide

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN BINDING PROTEIN 1; BINDING PROTEIN; CALCITONIN RECEPTOR; RECEPTOR ACTIVITY MODIFYING PROTEIN; UNCLASSIFIED DRUG; ADRENOMEDULLIN RECEPTOR; PEPTIDE; RECEPTOR;

EID: 0037295449     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-4804(02)00086-0     Document Type: Review
Times cited : (28)

References (56)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus D.C., Linde-Zwirble W.T., Lidicker J., Clermont G., Carcillo J., Pinsky M.R. Epidemiology of severe sepsis in the United States Analysis of incidence, outcome, and associated costs of care . Crit Care Med. 29:2001;1303.
    • (2001) Crit Care Med. , vol.29 , pp. 1303
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 2
    • 0018349233 scopus 로고
    • Effect of sepsis on tissue adenine nucleotide levels
    • Chaudry I.H., Wichterman K.A., Baue A.E. Effect of sepsis on tissue adenine nucleotide levels. Surgery. 85:1979;205.
    • (1979) Surgery , vol.85 , pp. 205
    • Chaudry, I.H.1    Wichterman, K.A.2    Baue, A.E.3
  • 3
    • 0030004108 scopus 로고    scopus 로고
    • Mechanism of hepatocellular dysfunction during hyperdynamic sepsis
    • Wang P., Chaudry I.H. Mechanism of hepatocellular dysfunction during hyperdynamic sepsis. Am. J. Physiol. 270:1996;R927.
    • (1996) Am. J. Physiol. , vol.270 , pp. 927
    • Wang, P.1    Chaudry, I.H.2
  • 4
    • 0032832718 scopus 로고    scopus 로고
    • Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis
    • Yang S., Cioffi W.G., Bland K.I., Chaudry I.H., Wang P. Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis. J. Trauma. 47:1999;706.
    • (1999) J. Trauma , vol.47 , pp. 706
    • Yang, S.1    Cioffi, W.G.2    Bland, K.I.3    Chaudry, I.H.4    Wang, P.5
  • 5
    • 0026327673 scopus 로고
    • Increase in hepatic blood flow during early sepsis is due to increased portal blood flow
    • Wang P., Ba Z.F., Chaudry I.H. Increase in hepatic blood flow during early sepsis is due to increased portal blood flow. Am. J. Physiol. 261:1991;R1507.
    • (1991) Am. J. Physiol. , vol.261 , pp. 1507
    • Wang, P.1    Ba, Z.F.2    Chaudry, I.H.3
  • 6
    • 0032133776 scopus 로고    scopus 로고
    • Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): Are we winning the battle?
    • Baue A.E., Durham R., Faist E. Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF) Are we winning the battle? Shock. 10:1998;79.
    • (1998) Shock , vol.10 , pp. 79
    • Baue, A.E.1    Durham, R.2    Faist, E.3
  • 7
    • 0018964280 scopus 로고
    • Sepsis and septic shock: A review of laboratory models and a proposal
    • Wichterman K.A., Baue A.E., Chaudry I.H. Sepsis and septic shock A review of laboratory models and a proposal . J. Surg. Res. 29:1980;189.
    • (1980) J. Surg. Res. , vol.29 , pp. 189
    • Wichterman, K.A.1    Baue, A.E.2    Chaudry, I.H.3
  • 9
    • 0033852124 scopus 로고    scopus 로고
    • Production and clearance sites of two molecular forms of adrenomedullin in human plasma
    • Nishikimi T., Matsuoka H., Shimada K., Matsuo H., Kangawa K. Production and clearance sites of two molecular forms of adrenomedullin in human plasma. Am. J. Hypertens. 13:2000;1032.
    • (2000) Am. J. Hypertens. , vol.13 , pp. 1032
    • Nishikimi, T.1    Matsuoka, H.2    Shimada, K.3    Matsuo, H.4    Kangawa, K.5
  • 10
    • 0034723350 scopus 로고    scopus 로고
    • Adrenomedullin: Potential in physiology and pathophysiology
    • Jougasaki M., Burnett J.C. Jr. Adrenomedullin Potential in physiology and pathophysiology . Life Sci. 66:2000;855.
    • (2000) Life Sci. , vol.66 , pp. 855
    • Jougasaki, M.1    Burnett J.C., Jr.2
  • 14
    • 0032134917 scopus 로고    scopus 로고
    • Up-regulation of a novel potent vasodilatory peptide adrenomedullin during polymicrobial sepsis
    • Wang P., Zhou M., Ba Z.F., Cioffi W.G., Chaudry I.H. Up-regulation of a novel potent vasodilatory peptide adrenomedullin during polymicrobial sepsis. Shock. 10:1998;118.
    • (1998) Shock , vol.10 , pp. 118
    • Wang, P.1    Zhou, M.2    Ba, Z.F.3    Cioffi, W.G.4    Chaudry, I.H.5
  • 15
    • 0028954392 scopus 로고
    • Interleukin-1, tumor necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells
    • Sugo S., Minamino N., Shoji H., Kangawa K., Kitamura K., Eto T., Matsio H. Interleukin-1, tumor necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 207:1995;25.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 25
    • Sugo, S.1    Minamino, N.2    Shoji, H.3    Kangawa, K.4    Kitamura, K.5    Eto, T.6    Matsio, H.7
  • 16
    • 0028120332 scopus 로고
    • Production and secretion of adrenomedullin from vascular smooth muscle cells: Augmented production by tumor necrosis factor-α
    • Sugo S., Minamino N., Shoji H., Kangawa K., Kitamura K., Eto T., Matsuo H. Production and secretion of adrenomedullin from vascular smooth muscle cells Augmented production by tumor necrosis factor-α Biochem. Biophys. Res. Commun. 203:1994;719.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 719
    • Sugo, S.1    Minamino, N.2    Shoji, H.3    Kangawa, K.4    Kitamura, K.5    Eto, T.6    Matsuo, H.7
  • 17
    • 0031737024 scopus 로고    scopus 로고
    • Production and secretion of adrenomedullin in cultured rat cardiac myocytes and nonmyocytes: Stimulation by interleukin-1β and tumor necrosis factor-α
    • Horio T., Nishikimi T., Yoshihara F., Nagaya N., Matsuo H., Takishita S., Kangawa K. Production and secretion of adrenomedullin in cultured rat cardiac myocytes and nonmyocytes Stimulation by interleukin-1β and tumor necrosis factor-α Endocrinology. 139:1998;4576.
    • (1998) Endocrinology , vol.139 , pp. 4576
    • Horio, T.1    Nishikimi, T.2    Yoshihara, F.3    Nagaya, N.4    Matsuo, H.5    Takishita, S.6    Kangawa, K.7
  • 18
    • 0025951812 scopus 로고
    • The complex pattern of cytokines in sepsis: Association between prostaglandins, cachectin and interleukins
    • Ertel W., Morrison M.H., Wang P., Ba Z.F., Ayala A., Chaudry I.H. The complex pattern of cytokines in sepsis Association between prostaglandins, cachectin and interleukins . Ann. Surg. 214:1991;141.
    • (1991) Ann. Surg. , vol.214 , pp. 141
    • Ertel, W.1    Morrison, M.H.2    Wang, P.3    Ba, Z.F.4    Ayala, A.5    Chaudry, I.H.6
  • 19
    • 0031001334 scopus 로고    scopus 로고
    • Mechanism of hepatocellular dysfunction during early sepsis: Key role of increased gene expression and release of proinflammatory cytokines tumor necrosis factor and interleukin-6
    • Wang P., Ba Z.F., Chaudry I.H. Mechanism of hepatocellular dysfunction during early sepsis Key role of increased gene expression and release of proinflammatory cytokines tumor necrosis factor and interleukin-6 . Arch. Surg. 132:1997;364.
    • (1997) Arch. Surg. , vol.132 , pp. 364
    • Wang, P.1    Ba, Z.F.2    Chaudry, I.H.3
  • 20
    • 0003520060 scopus 로고    scopus 로고
    • Up-regulation of rat adrenomedullin gene expression by endotoxin: Relation to nitric oxide synthesis
    • So S., Hattori Y., Kasai K., Shimoda S.I., Gross S.S. Up-regulation of rat adrenomedullin gene expression by endotoxin Relation to nitric oxide synthesis . Life Sci. 58:1996;PL309.
    • (1996) Life Sci. , vol.58 , pp. 309
    • So, S.1    Hattori, Y.2    Kasai, K.3    Shimoda, S.I.4    Gross, S.S.5
  • 22
    • 0034885177 scopus 로고    scopus 로고
    • The small intestine is an important source of adrenomedullin release during polymicrobial sepsis
    • Zhou M., Chaudry I.H., Wang P. The small intestine is an important source of adrenomedullin release during polymicrobial sepsis. Am. J. Physiol Regul. Integr. Comp. Physiol. 281:2001;R654.
    • (2001) Am. J. Physiol Regul. Integr. Comp. Physiol. , vol.281 , pp. 654
    • Zhou, M.1    Chaudry, I.H.2    Wang, P.3
  • 23
    • 0035964986 scopus 로고    scopus 로고
    • The role of lipopolysaccharide in stimulating adrenomedullin production during polymicrobial sepsis
    • Yang S., Zhou M., Chaudry I.H., Wang P. The role of lipopolysaccharide in stimulating adrenomedullin production during polymicrobial sepsis. Biochim. Biophys. Acta. 1537:2001;167.
    • (2001) Biochim. Biophys. Acta , vol.1537 , pp. 167
    • Yang, S.1    Zhou, M.2    Chaudry, I.H.3    Wang, P.4
  • 26
    • 0032961867 scopus 로고    scopus 로고
    • Pulmonary clearance of adrenomedullin is reduced during the late stage of sepsis
    • Ornan D.A., Chaudry I.H., Wang P. Pulmonary clearance of adrenomedullin is reduced during the late stage of sepsis. Biochim. Biophys. Acta. 1427:1999;315.
    • (1999) Biochim. Biophys. Acta , vol.1427 , pp. 315
    • Ornan, D.A.1    Chaudry, I.H.2    Wang, P.3
  • 27
    • 0037165717 scopus 로고    scopus 로고
    • Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis
    • Ornan D.A., Chaudry I.H., Wang P. Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis. Biochim. Biophys. Acta. 1586:2002;299.
    • (2002) Biochim. Biophys. Acta , vol.1586 , pp. 299
    • Ornan, D.A.1    Chaudry, I.H.2    Wang, P.3
  • 28
    • 0028845450 scopus 로고
    • Endothelium-dependent relaxation is depressed at the macro- and microcirculatory levels during sepsis
    • Wang P., Ba Z.F., Chaudry I.H. Endothelium-dependent relaxation is depressed at the macro- and microcirculatory levels during sepsis. Am. J. Physiol. 269:1995;R988.
    • (1995) Am. J. Physiol. , vol.269 , pp. 988
    • Wang, P.1    Ba, Z.F.2    Chaudry, I.H.3
  • 29
    • 0031002742 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase is downregulated during hyperdynamic sepsis
    • Zhou M., Wang P., Chaudry I.H. Endothelial nitric oxide synthase is downregulated during hyperdynamic sepsis. Biochim. Biophys. Acta. 1335:1997;182.
    • (1997) Biochim. Biophys. Acta , vol.1335 , pp. 182
    • Zhou, M.1    Wang, P.2    Chaudry, I.H.3
  • 30
    • 0033656940 scopus 로고    scopus 로고
    • Upregulation of inducible nitric oxide synthase and nitric oxide occurs later than the onset of the hyperdynamic response during sepsis
    • Shieh P., Zhou M., Ornan D.A., Chaudry I.H., Wang P. Upregulation of inducible nitric oxide synthase and nitric oxide occurs later than the onset of the hyperdynamic response during sepsis. Shock. 13:2000;325.
    • (2000) Shock , vol.13 , pp. 325
    • Shieh, P.1    Zhou, M.2    Ornan, D.A.3    Chaudry, I.H.4    Wang, P.5
  • 31
    • 0034072363 scopus 로고    scopus 로고
    • Is prostacyclin responsible for producing the hyperdynamic response during early sepsis?
    • Wang P., Zhou M., Cioffi W.G., Bland K.I., Ba Z.F., Chaudry I.H. Is prostacyclin responsible for producing the hyperdynamic response during early sepsis? Crit. Care Med. 28:2000;1534.
    • (2000) Crit. Care Med. , vol.28 , pp. 1534
    • Wang, P.1    Zhou, M.2    Cioffi, W.G.3    Bland, K.I.4    Ba, Z.F.5    Chaudry, I.H.6
  • 32
    • 0035014359 scopus 로고    scopus 로고
    • The small intestine plays an important role in upregulating calcitonin gene-related peptide during sepsis
    • Zhou M., Arthur A.J., Ba Z.F., Chaudry I.H., Wang P. The small intestine plays an important role in upregulating calcitonin gene-related peptide during sepsis. Am. J. Physiol Regul. Integr. Comp Physiol. 280:2001;R382.
    • (2001) Am. J. Physiol Regul. Integr. Comp Physiol , vol.280 , pp. 382
    • Zhou, M.1    Arthur, A.J.2    Ba, Z.F.3    Chaudry, I.H.4    Wang, P.5
  • 33
    • 0029382098 scopus 로고
    • Sustained elevation in circulating catecholamine levels during polymicrobial sepsis
    • Hahn P.Y., Wang P., Tait S.M., Ba Z.F., Reich S.S., Chaudry I.H. Sustained elevation in circulating catecholamine levels during polymicrobial sepsis. Shock. 4:1995;269.
    • (1995) Shock , vol.4 , pp. 269
    • Hahn, P.Y.1    Wang, P.2    Tait, S.M.3    Ba, Z.F.4    Reich, S.S.5    Chaudry, I.H.6
  • 34
    • 0032439411 scopus 로고    scopus 로고
    • The pivotal role of adrenomedullin in producing hyperdynamic circulation during the early stage of sepsis
    • Wang P., Ba Z.F., Cioffi W.G., Bland K.I., Chaudry I.H. The pivotal role of adrenomedullin in producing hyperdynamic circulation during the early stage of sepsis. Arch. Surg. 133:1998;1298.
    • (1998) Arch. Surg. , vol.133 , pp. 1298
    • Wang, P.1    Ba, Z.F.2    Cioffi, W.G.3    Bland, K.I.4    Chaudry, I.H.5
  • 36
    • 0035747129 scopus 로고    scopus 로고
    • The role of adrenomedullin in producing differential hemodynamic responses during sepsis
    • Koo D.J., Zhou M., Chaudry I.H., Wang P. The role of adrenomedullin in producing differential hemodynamic responses during sepsis. J. Surg. Res. 95:2001;207.
    • (2001) J. Surg. Res. , vol.95 , pp. 207
    • Koo, D.J.1    Zhou, M.2    Chaudry, I.H.3    Wang, P.4
  • 37
    • 0034213969 scopus 로고    scopus 로고
    • Mechanism of the beneficial effects of pentoxifylline during sepsis: Maintenance of adrenomedullin responsiveness and downregulation of proinflammatory cytokines
    • Koo D.J., Yoo P., Cioffi W.G., Bland K.I., Chaudry I.H., Wang P. Mechanism of the beneficial effects of pentoxifylline during sepsis Maintenance of adrenomedullin responsiveness and downregulation of proinflammatory cytokines . J. Surg. Res. 91:2000;70.
    • (2000) J. Surg. Res. , vol.91 , pp. 70
    • Koo, D.J.1    Yoo, P.2    Cioffi, W.G.3    Bland, K.I.4    Chaudry, I.H.5    Wang, P.6
  • 38
    • 0032888183 scopus 로고    scopus 로고
    • Pentoxifylline prevents the transition from the hyperdynamic to hypodynamic response during sepsis
    • Yang S., Zhou M., Koo D.J., Chaudry I.H., Wang P. Pentoxifylline prevents the transition from the hyperdynamic to hypodynamic response during sepsis. Am. J. Physiol. 277:1999;H1036.
    • (1999) Am. J. Physiol. , vol.277 , pp. 1036
    • Yang, S.1    Zhou, M.2    Koo, D.J.3    Chaudry, I.H.4    Wang, P.5
  • 40
    • 0033054409 scopus 로고    scopus 로고
    • RAMPs: Accessory proteins for seven transmembrane domain receptors
    • Foord S.M., Marshall F.H. RAMPs Accessory proteins for seven transmembrane domain receptors . Trends Pharmacol. Sci. 20:1999;184.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 184
    • Foord, S.M.1    Marshall, F.H.2
  • 41
    • 0033013790 scopus 로고    scopus 로고
    • The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor
    • Fraser N.J., Wise A., Brown J., McLatchie L.M., Main M.J., Foord S.M. The amino terminus of receptor activity modifying proteins is a critical determinant of glycosylation state and ligand binding of calcitonin receptor-like receptor. Mol. Pharmacol. 55:1999;1054.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 1054
    • Fraser, N.J.1    Wise, A.2    Brown, J.3    McLatchie, L.M.4    Main, M.J.5    Foord, S.M.6
  • 43
    • 0035025773 scopus 로고    scopus 로고
    • CAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels
    • Zhang X., Hintze T.H. cAMP signal transduction cascade, a novel pathway for the regulation of endothelial nitric oxide production in coronary blood vessels. Arterioscler. Thromb. Vasc. Biol. 21:2001;797.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 797
    • Zhang, X.1    Hintze, T.H.2
  • 45
  • 46
    • 0036724151 scopus 로고    scopus 로고
    • Adrenomedullin binding protein-1 modulates vascular responsiveness to adrenomedullin in late sepsis
    • Zhou M., Ba Z.F., Chaudry I.H., Wang P. Adrenomedullin binding protein-1 modulates vascular responsiveness to adrenomedullin in late sepsis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283:2002;R553.
    • (2002) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.283 , pp. 553
    • Zhou, M.1    Ba, Z.F.2    Chaudry, I.H.3    Wang, P.4
  • 47
    • 0031454520 scopus 로고    scopus 로고
    • Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats
    • Chao J., Jin L., Lin K.F., Chao L. Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats. Hypertens. Res. 20:1997;269.
    • (1997) Hypertens. Res. , vol.20 , pp. 269
    • Chao, J.1    Jin, L.2    Lin, K.F.3    Chao, L.4
  • 48
    • 0033670493 scopus 로고    scopus 로고
    • Adrenomedullin gene delivery attenuates hypertension, cardiac remodeling, and renal injury in deoxycorticosterone acetate-salt hypertensive rats
    • Dobrzynski E., Wang C., Chao J., Chao L. Adrenomedullin gene delivery attenuates hypertension, cardiac remodeling, and renal injury in deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 36:2000;995.
    • (2000) Hypertension , vol.36 , pp. 995
    • Dobrzynski, E.1    Wang, C.2    Chao, J.3    Chao, L.4
  • 49
    • 0034284180 scopus 로고    scopus 로고
    • Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats
    • Zhang J.J., Yoshida H., Chao L., Chao J. Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats. Hum. Gene Ther. 11:2000;1817.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 1817
    • Zhang, J.J.1    Yoshida, H.2    Chao, L.3    Chao, J.4
  • 50
    • 0034989492 scopus 로고    scopus 로고
    • Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats
    • Wang C., Dobrzynski E., Chao J., Chao L. Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats. Am. J. Physiol. Renal Physiol. 280:2001;F964.
    • (2001) Am. J. Physiol. Renal Physiol. , vol.280 , pp. 964
    • Wang, C.1    Dobrzynski, E.2    Chao, J.3    Chao, L.4
  • 52
    • 0033305261 scopus 로고    scopus 로고
    • Adrenomedullin binding protein in the plasma of multiple species: Characterization by radioligand blotting
    • Elsasser T.H., Kahl S., Martinez A., Montuenga L.M., Pio R., Cuttitta F. Adrenomedullin binding protein in the plasma of multiple species Characterization by radioligand blotting . Endocrinology. 140:1999;4908.
    • (1999) Endocrinology , vol.140 , pp. 4908
    • Elsasser, T.H.1    Kahl, S.2    Martinez, A.3    Montuenga, L.M.4    Pio, R.5    Cuttitta, F.6
  • 53
    • 0035853722 scopus 로고    scopus 로고
    • Complement factor H is a serum binding protein for adrenomedullin. The resulting complex modulates the bioactivities of both partners
    • Pio R., Martinez A., Unsworth E.J., Kowalak J.A., Bengoechea J.A., Zipfel P.F., Elsasser T.H., Cuttitta F. Complement factor H is a serum binding protein for adrenomedullin. The resulting complex modulates the bioactivities of both partners. J. Biol. Chem. 276:2001;12292.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12292
    • Pio, R.1    Martinez, A.2    Unsworth, E.J.3    Kowalak, J.A.4    Bengoechea, J.A.5    Zipfel, P.F.6    Elsasser, T.H.7    Cuttitta, F.8
  • 54
    • 0033557890 scopus 로고    scopus 로고
    • Rat-2 fibroblasts express specific adrenomedullin receptors, but not calcitonin-gene-related-peptide receptors, which mediate increased intracellular cAMP and inhibit mitogen-activated protein kinase activity
    • Coppock H.A., Owji A.A., Austin C., Upton P.D., Jackson M.L., Gardiner J.V., Ghatei M.A., Bloom S.R., Smith D.M. Rat-2 fibroblasts express specific adrenomedullin receptors, but not calcitonin-gene-related-peptide receptors, which mediate increased intracellular cAMP and inhibit mitogen-activated protein kinase activity. Biochem. J. 338:1999;15.
    • (1999) Biochem. J. , vol.338 , pp. 15
    • Coppock, H.A.1    Owji, A.A.2    Austin, C.3    Upton, P.D.4    Jackson, M.L.5    Gardiner, J.V.6    Ghatei, M.A.7    Bloom, S.R.8    Smith, D.M.9
  • 55
    • 0036830201 scopus 로고    scopus 로고
    • Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: Role of adrenomedullin and adrenomedullin binding protein-1
    • Yang S., Zhou M., Chaudry I.H., Wang P. Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis Role of adrenomedullin and adrenomedullin binding protein-1 . Ann. Surg. 236:2002;625.
    • (2002) Ann. Surg. , vol.236 , pp. 625
    • Yang, S.1    Zhou, M.2    Chaudry, I.H.3    Wang, P.4
  • 56
    • 0036884978 scopus 로고    scopus 로고
    • Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin binding protein-1 in sepsis: Downregulation of proinflammatory cytokines
    • Yang S., Zhou M., Fowler D.E., Wang P. Mechanisms of the beneficial effect of adrenomedullin and adrenomedullin binding protein-1 in sepsis Downregulation of proinflammatory cytokines . Crit. Care Med. 30:2002;2729.
    • (2002) Crit. Care Med. , vol.30 , pp. 2729
    • Yang, S.1    Zhou, M.2    Fowler, D.E.3    Wang, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.