Differentiation and migration of astrocytes in the spinal cord following dorsal root injury in the adult rat

European Journal of Neuroscience

Volumn 17, Issue 4, 2003, Pages 782-790

  Kozlova, Elena N ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Axotomy; Gliogenesis; Nestin; S100 protein; Subpial astrocytes

Indexed keywords

BROXURIDINE; CALCIUM BINDING PROTEIN; CALVASCULIN; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DORSAL ROOT; FEMALE; GRAY MATTER; MICROGLIA; NERVE DEGENERATION; NERVE FIBER; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; SPINAL CORD DORSAL HORN; SPINE INJURY; WHITE MATTER;

ANIMALS; ASTROCYTES; BROMODEOXYURIDINE; CELL COUNT; CELL DIFFERENTIATION; CELL MOVEMENT; CYCLIN-DEPENDENT KINASE INHIBITOR P16; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; LAMINECTOMY; NERVE TISSUE PROTEINS; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; SPINAL NERVE ROOTS; TIME FACTORS;

EID: 0037294124     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02518.x     Document Type: Article

References (35)

1. 3 by cells in the normal and injured mouse spinal cord. J. Neuropathol. Exp. Neurol., 21, 597-609.
2. Aldskogius, H. & Kozlova, E.N. (1998) Central neuron-glial and glial-glial interactions following axon injury. Prog. Neurobiol., 55, 1-26.
3. Alvarez-Buylla, A. & Garcia-Verdugo, J.M. (2002) Neurogenesis in adult subventricular zone. J. Neurosci., 22, 629-634.
4. Brook, G.A., Perez-Bouza, A., Noth, J. & Nacimiento, W. (1999) Astrocytes re-express nestin in deafferented target territories of the adult rat hippocampus. Neuroreport, 10, 1007-1011.
5. Choi, B.H. (1981) Radial glia of developing human fetal spinal cord: Golgi, immunohistochemical and electron microscopic study. Brain Res., 227, 249-267.
6. Choi, B.H. & Kim, R.C. (1985) Expression of glial fibrillary acidic protein by immature oligodendroglia and its implications. J. Neuroimmunol., 8, 215-235.
7. Clarke, S.R., Shetty, A.K., Bradley, J.L. & Turner, D.A. (1994) Reactive astrocytes express the embryonic intermediate neurofilament nestin. Neuroreport, 5, 1885-1888.
8. Culican, S.M., Baumrind, N.L., Yamamoto, M. & Pearlman, A.L. (1990) Cortical radial glia: identification in tissue culture and evidence for their transformation to astrocytes. J. Neurosci., 10, 684-692.
9. Dutton, R. & Bartlett, P.F. (2000) Precursor cells in the subventricular zone of the adult mouse are actively inhibited from differentiating into neurons. Dev. Neurosci., 22, 96-105.
10. Frisén, J., Johansson, C.B., Török, C., Risling, M. & Lendahl, U. (1995) Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury. J. Cell Biol., 131, 453-464.
11. Fujita, S. (1965) An autoradiographic study on the origin and fate of the sub-pial glioblast in the embryonic chick spinal cord. J. Comp. Neurol., 124, 51-60.
12. Gage, F.H., Kempermann, G., Palmer, T.D., Peterson, D.A. & Ray, J. (1998) Multipotent progenitor cells in the adult dentate gyrus. J. Neurobiol., 36, 249-266.
13. Gilmore, S.A. (1971) Neuroglial population in the spinal white matter of neonatal and early postnatal rats: an autoradiographic study of numbers of neuroglia and changes in their proliferative activity. Anat. Rec., 171, 283-291.
14. Hirano, M. & Goldman, J.E. (1988) Gliogenesis in rat spinal cord: evidence for origin of astrocytes and oligodendrocytes from radial precursors. J. Neurosci. Res., 21, 155-167.
15. Holmin, S., Almqvist, P., Lendahl, U. & Mathiesen, T. (1997) Adult nestin-expressing subependymal cells differentiate to astrocytes in response to brain injury. Eur. J. Neurosci., 9, 65-75.
16. Horner, P.J., Power, A.E., Kempermann, G., Kuhn, H.G., Palmer, T.D., Winkler, J., Thal, L.J. & Gage, F.H. (2000) Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J. Neurosci., 20, 2218-2228.
17. Jensen, M.B., Gonzalez, B., Castellano, B. & Zimmer, J. (1994) Microglial and astroglial reactions to anterograde axonal degeneration: a histochemical and immunocytochemical study of the adult rat fascia dentata after entorhinal perforant path lesions. Exp. Brain Res., 98, 245-260.
18. Kirchenbaum, B., Nedergaard, M., Preuss, A., Barami, K., Fraser, R.A. & Goldman, S.A. (1994) In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cereb. Cortex, 4, 576-589.
19. Kozlova, E.N. (2002) Role of Mts1/S100A4 protein in the CNS. In Aldskogius, H. & Fraher, J. (eds), Glial Interfaces in the Nervous System. IOS Press, Amsterdam, pp. 117-128.
20. Kozlova, E.N. & Lukanidin, E. (1999) Metastasis-associated Mts1 (S100A4) protein is selectively expressed in white matter astrocytes and is up-regulated after peripheral nerve or dorsal root injury. Glia, 27, 249-258.
21. Kozlova, E.N. & Lukanidin, E. (2002) Mts1 protein expression in the CNS after injury. Glia, 37, 337-348.
22. Lendahl, U., Zimmerman, L.B. & McKay, R.D. (1990) CNS stem cells express a new class of intermediate filament protein. Cell, 60, 585-595.
23. Lin, R.C., Matesic, D.F., Marvin, M., McKay, R.D. & Brustle, O. (1995) Re-expression of the intermediate filament nestin in reactive astrocytes. Neurobiol. Dis., 2, 79-85.
24. Liu, L., Persson, J.K.E., Svensson, M. & Aldskogius, H. (1998) Glial cell responses, complement and clusterin in the central nervous system following dorsal root transection. Glia, 23, 221-238.
25. Liu, L., Rudin, M. & Kozlova, E.N. (2000) Glial cell proliferation in the spinal cord after dorsal rhizotomy or sciatic nerve transection in the adult rat. Exp. Brain Res., 131, 64-73.
26. Louissaint, A. Jr, Rao, S., Leventhal, C. & Goldman, S.A. (2002) Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron, 34, 945-960.
27. Marin-Padilla, M. (1995) Prenatal development of fibrous (white matter), protoplasmic (gray matter), and layer I astrocytes in the human cerebral cortex: a Golgi study. J. Comp. Neurol., 357, 554-572.
28. Murray, M., Wang, S.D., Goldberger, M.E. & Levitt, P. (1990) Modification of astrocytes in the spinal cord following dorsal root or peripheral nerve lesions. Exp. Neurol., 110, 248-257.
29. Namiki, J. & Tator, C.H. (1999) Cell proliferation and nestin expression in the ependyma of the adult rat spinal cord after injury. J. Neuropathol. Exp. Neurol., 58, 489-498.
30. Peretto, P., Merighi, A., Fasolo, A. & Bonfanti, L. (1999) The subependymal layer in rodents: a site of structural plasticity and cell migration in the adult mammalian brain. Brain Res. Bull., 42, 9-21.
31. Quinonero, J., Collin, C., Villaroya, H., Collins, P. & Jacgue, C. (1993) Migration pathways, differentiation and survival of macroglial cells from a xenograft implanted into the thalamus of newborn mice. Int. J. Neurosci., 11, 545-554.
32. Rietze, R., Poulin, P. & Weiss, S. (2000) Mitotically active cells that generate neurons and astrocytes are present in multiple regions of the adult mouse hippocampus. J. Comp. Neurol., 424, 397-408.
33. Shibuya, S., Miyamoto, O., Auer, R., Itano, T., Mori, S. & Norimatsu, H. (2002) Embryonic intermediate filament, nestin, expression following traumatic spinal cord injury in adult rats. Neuroscience, 114, 905-916.
34. Shihabuddin, L.S., Ray, J. & Gage, F.H. (1997) FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord. Exp. Neurol., 148, 577-586.
35. Weiss, S., Dunne, C., Hewson, J., Wohl, C., Wheatley, M., Peterson, A.C. & Reynolds, B.A. (1996) Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J. Neurosci., 16, 7599-7609.