Inhibitory effects of atropine and hexamethonium on the angiotensin II-induced contractions of rat anococcygeus smooth muscles

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 367, Issue 2, 2003, Pages 176-182

  De Godoy, Márcio Augusto Fressatto ^a   Accorsi Mendonça, Daniela ^a   De Oliveira, Ana Maria ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

methyl p tyrosine; Angiotensin II; Anococcygeus; Atropine; Cholinergic transmission; Hexamethonium; Reserpine; Yohimbine

Indexed keywords

ANGIOTENSIN; ATROPINE; HEXAMETHONIUM; N(G) NITROARGININE METHYL ESTER; NEOSTIGMINE; YOHIMBINE;

ANIMAL TISSUE; ANOCOCCYGEUS MUSCLE; ARTICLE; CHOLINERGIC TRANSMISSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; MALE; MUSCLE CONTRACTION; NONHUMAN; RAT; SYMPATHECTOMY;

ANGIOTENSIN II; ANIMALS; ATROPINE; CHOLINERGIC ANTAGONISTS; CHOLINESTERASE INHIBITORS; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEXAMETHONIUM; MALE; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEOSTIGMINE; NG-NITROARGININE METHYL ESTER; NICOTINIC ANTAGONISTS; RATS; RATS, WISTAR; VASOCONSTRICTOR AGENTS; YOHIMBINE;

EID: 0037291856     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-002-0659-2     Document Type: Article

References (34)

1. Buyukcoskun NI, Gulec G, Ozluk K (2001) A central link between angiotensinergic and cholinergic systems; role of vasopressin. Peptides 22:1415-1420
2. Dail WG, Carrillo Y, Walton G (1990) Innervation of the anococcygeus muscle of the rat. Cell Tissue Res 259:139-146
3. Dail WG, Galloway B, Bordegaray J (1993) NADPH diaphorase innervation of the rat anococcygeus and retractor penis muscles. Neurosci Letter 160:17-20
4. De Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T (2000) International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52:415-470
5. 2 angiotensin receptors in rat anococcygeus smooth muscle. J Pharmacol Exp Ther 303:333-339
6. Doggrell SA, Woodruff GN (1978) Effects of drugs on the accumulation and spontaneous release of noradrenaline in the rat anococcygeus muscle. Br J Pharmacol 63:465-470
7. Fabiani ME, Story DF (1995) Effects of cromakalim, pinacidil and glibenclamide on cholinergic transmission in rat isolated atria. Pharmacol Res 32:155-163
8. Fabiani ME, Dinh DT, Story DF (1997) Interaction of the reninangiotensin system, bradykinin and sympathetic nerves with cholinergic transmission in the rat isolated trachea. Br J Pharmacol 122:1089-1098
9. Gibbins IL, Haller CJ (1979) Ultrastructural identification of non-cholinergic, non-adrenergic nerves in the rat anococcygeus muscle. Cell Tissue Res 200:257-271
10. Gillespie JS (1972) The rat anococcygeus muscle and its response to nerve stimulation and to some drugs. Br J Pharmacol 45:404-416
11. Gillespie JS, McGrath JC (1973) The spinal origin of the motor and inhibitory innervation of the rat anococcygeus muscles. J Physiol 230:659-672
12. Gillespie JS, McGrath JC (1974) The effect of pithing and of nerve stimulation on the depletion of noradrenaline by reserpine in the rat anococcygeus muscle and vas deferens. Br J Pharmacol 52:585-590
13. G-monomethyl L-arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation. Br J Pharmacol 98:1080-1082
14. Hobbs SF, Potter EK (1985) Angiotensin inhibits gastric and tracheal contractile responses to peripheral parasympathetic stimulation. J Auton Nerv Syst 14:75-79
15. Iravani MM, Zar MA (1997) The presence and the effects of neuropeptide Y in rat anococcygeus muscle. Eur J Pharmacol 29:75-82
16. James MK, Leighton HJ (1987) Analysis of putative alpha-1 s adrenoceptor agonism by Sgd 101/75 in the rat anococcygeus muscle. J Pharmacol Exp Ther 242:772-776
17. Li C, Majewski H, Rand M (1988) Facilitation of noradrenaline release from sympathetic nerves in rat anococcygeus muscle by activation of prejunctional β-adrenoceptors and angiotensin receptors. Br J Pharmacol 98:385-392
18. Li CG, Rand MJ (1989) Prejunctional inhibition of non-adrenergic non-cholinergic transmission in the rat anococcygeus muscle. Eur J Pharmacol 168:107-110
19. Loiacono RE, Story DF (1986) Effect of alpha-adrenoceptor agonists and antagonists on cholinergic transmission in guinea-pig isolated atria. Naunyn-Schmiedebergs Arch Pharmacol 334:40-47
20. Oliveira AM, Bendhack LM (1992) Dopamine-induced contractile responses of the rat anococcygeus muscle. Arch Int Pharmacodyn Ther 316:97-104
21. Potter EK (1982a) Angiotensin inhibits action of vagus nerve at the heart. Br J Pharmacol 75:9-11
22. Potter EK (1982b) Peripheral inhibition of the parasympathetic nervous system by angiotensin. Clin Exp Pharmacol Physiol 7:51-55
23. Rajani AP, Gulati OD (1988) Evidence for multiple prejunctional receptor sites in rat isolated anococcygeus muscle. Arch Int Pharmacodyn Ther 292:86-100
24. Ramagopal MV, Leighton HL (1989) Analysis of the presence of postjunctional alpha-2 adrenoceptors in the rat anococcygeus muscle. J Pharmacol Exp Ther 250:492-499
25. Rand MJ, Li CG (1990) Nitric oxide mediates non-adrenergic non-cholinergic relaxation in some neuroeffector systems: examples of nitrergic transmission. Eur J Pharmacol 183:1144
26. Rand MJ, Li CG (1992) Activation of noradrenergic and nitrergic mechanisms in the rat anococcygeus muscle by nicotine. Clin Exp Pharmacol Physiol 19:103-111
27. Rechtman M, Majewski HA (1993) A facilitatory effect of anti-angiotensin drugs on vagal bradycardia in the pithed rat and guinea-pig. Br J Pharmacol 10:289-296
28. Tamaoki J, Yamauchi F, Konno K (1992) Effects of angiotensin peptides on cholinergic neurotransmission in rabbit tracheal smooth muscle. Res Commun Chem Pathol Pharmacol 77:259-272
29. ++. Arch Int Pharmacodyn 291:104-112
30. Tsuda K, Tsuda S, Nishio I, Masuyama Y, Goldstein M (1998) Captopril inhibits both dopaminergic and cholinergic neurotransmission in the central nervous system. Clin Exp Pharmacol Physiol 25:904-907
31. Wang X, Yang H, Raizada MK (2001) Angiotensin II increases vesicular trafficking in brain neurons. Hypertension 37:677-682
32. Weiser M, Mutschler E, Lambrecht G (1997) Characterization of postjunctional muscarinic receptors mediating contraction in rat anococcygeus muscle. Naunyn-Schmiedebergs Arch Pharmacol 356:671-677
33. 4 receptors. Naunyn-Schmiedebergs Arch Pharmacol 356:712-720
34. Yamawaki I, Tamaoki J, Yamauchi F, Konno K (1992) Angiotensin II potentiates neurally mediated contraction of rabbit airway smooth muscle. Respir Physiol 89:239-247