메뉴 건너뛰기




Volumn 35, Issue 2, 2003, Pages 149-156

L-Carnitine alters nitric oxide synthase activity in fibroblasts depending on the peroxisomal status

Author keywords

Carnitine deficiency; L Carnitine; Nitric oxide synthase; Oxidative stress; Peroxisomes

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; HYDROGEN PEROXIDE; NITRIC OXIDE SYNTHASE; CARNITINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FATTY ACID; NOS3 PROTEIN, HUMAN; PROTEIN;

EID: 0037290730     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(02)00183-8     Document Type: Article
Times cited : (16)

References (38)
  • 1
    • 0021024932 scopus 로고
    • Carnitine - Metabolism and functions
    • Bremer J. Carnitine - metabolism and functions. Physiol. Rev. 63:1983;1420-1480.
    • (1983) Physiol. Rev. , vol.63 , pp. 1420-1480
    • Bremer, J.1
  • 2
    • 0025561023 scopus 로고
    • Primary and secondary disorders of carnitine metabolism
    • De Vivo D.C., Tein I. Primary and secondary disorders of carnitine metabolism. Int. Pediatr. 5:1990;134-141.
    • (1990) Int. Pediatr. , vol.5 , pp. 134-141
    • De Vivo, D.C.1    Tein, I.2
  • 3
    • 0027166659 scopus 로고
    • Carnitine metabolism and human carnitine deficiency
    • Tanphaichitr V., Leelahagul P. Carnitine metabolism and human carnitine deficiency. Nutrition. 9:1993;246-254.
    • (1993) Nutrition , vol.9 , pp. 246-254
    • Tanphaichitr, V.1    Leelahagul, P.2
  • 4
    • 0033505786 scopus 로고    scopus 로고
    • The role of the carnitine system in peroxisomal fatty acid oxidation
    • Ramsay R.R. The role of the carnitine system in peroxisomal fatty acid oxidation. Am. J. Med. Sci. 318:1999;28-35.
    • (1999) Am. J. Med. Sci. , vol.318 , pp. 28-35
    • Ramsay, R.R.1
  • 5
    • 0033032120 scopus 로고    scopus 로고
    • Submitochondrial and subcellular distributions of the carnitine-acylcarnitine carrier
    • Fraser F., Zammit V.A. Submitochondrial and subcellular distributions of the carnitine-acylcarnitine carrier. FEBS Lett. 445:1999;41-44.
    • (1999) FEBS Lett. , vol.445 , pp. 41-44
    • Fraser, F.1    Zammit, V.A.2
  • 6
    • 0026948442 scopus 로고
    • L-carnitine: Metabolism, functions and value in pathology
    • Jacob C., Belleville F. L-carnitine: metabolism, functions and value in pathology. Pathol. Biol. (Paris). 40:1992;910-919.
    • (1992) Pathol. Biol. (Paris) , vol.40 , pp. 910-919
    • Jacob, C.1    Belleville, F.2
  • 7
    • 0027971960 scopus 로고
    • Reversal of valproic acid-associated impairment of carnitine uptake in cultured human skin fibroblasts
    • Tien I., Xie Z.W. Reversal of valproic acid-associated impairment of carnitine uptake in cultured human skin fibroblasts. Biochem. Biophys. Res. Commun. 204:1994;753-758.
    • (1994) Biochem. Biophys. Res. Commun. , vol.204 , pp. 753-758
    • Tien, I.1    Xie, Z.W.2
  • 8
    • 0025336324 scopus 로고
    • Determination of L-carnitine in biological fluids and tissues
    • Deufel T. Determination of L-carnitine in biological fluids and tissues. J. Clin. Chem. Clin. Biochem. 28:1990;307-311.
    • (1990) J. Clin. Chem. Clin. Biochem. , vol.28 , pp. 307-311
    • Deufel, T.1
  • 11
    • 0033964762 scopus 로고    scopus 로고
    • Mitochondrial role in life and death of the cell
    • Lee H.C., Wei Y.H. Mitochondrial role in life and death of the cell. J. Biomed. Sci. 7:2000;2-15.
    • (2000) J. Biomed. Sci. , vol.7 , pp. 2-15
    • Lee, H.C.1    Wei, Y.H.2
  • 12
    • 0030477745 scopus 로고    scopus 로고
    • Mammalian peroxisomes: Metabolism of oxygen and reactive oxygen species
    • Singh I. Mammalian peroxisomes: metabolism of oxygen and reactive oxygen species. Ann. N. Y. Acad. Sci. 804:1996;612-627.
    • (1996) Ann. N. Y. Acad. Sci. , vol.804 , pp. 612-627
    • Singh, I.1
  • 13
    • 0032581012 scopus 로고    scopus 로고
    • Progressive decline in the ability of calmodulin isolated from aged brain to activate the plasma membrane Ca-ATPase
    • Gao J., Yin D.H., Yao Y., Williams T.D., Squier T.C. Progressive decline in the ability of calmodulin isolated from aged brain to activate the plasma membrane Ca-ATPase. Biochemistry. 37:1998;9536-9548.
    • (1998) Biochemistry , vol.37 , pp. 9536-9548
    • Gao, J.1    Yin, D.H.2    Yao, Y.3    Williams, T.D.4    Squier, T.C.5
  • 15
    • 0032947296 scopus 로고    scopus 로고
    • Nitric oxide and mitochondrial respiration
    • Brown G.C. Nitric oxide and mitochondrial respiration. Biochim. Biophys. Acta. 1411:1999;351-369.
    • (1999) Biochim. Biophys. Acta. , vol.1411 , pp. 351-369
    • Brown, G.C.1
  • 17
    • 0031055817 scopus 로고    scopus 로고
    • Biochemistry of peroxisomes in health and disease
    • Singh I. Biochemistry of peroxisomes in health and disease. Mol. Cell. Biochem. 167:1997;1-29.
    • (1997) Mol. Cell. Biochem. , vol.167 , pp. 1-29
    • Singh, I.1
  • 18
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid
    • Aruoma O.I., Halliwell B., Hoey B.M., Butler J. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic. Biol. Med. 6:1989;593-597.
    • (1989) Free Radic. Biol. Med. , vol.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 19
    • 0025191219 scopus 로고
    • Isolation of nitric oxide synthase, a calmodulin-requiring enzyme
    • Bredt D.S., Snyder S.H. Isolation of nitric oxide synthase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. U.S.A. 87:1990;682-685.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 682-685
    • Bredt, D.S.1    Snyder, S.H.2
  • 20
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 21
    • 0027509770 scopus 로고
    • A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates
    • Miller N.J., Rice-Evans C., Davies M.J., Gopinathan V., Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. 84:1993;407-412.
    • (1993) Clin. Sci. , vol.84 , pp. 407-412
    • Miller, N.J.1    Rice-Evans, C.2    Davies, M.J.3    Gopinathan, V.4    Milner, A.5
  • 22
    • 0023554218 scopus 로고
    • Chemosensitivity testing of human colorectal carcinoma cell lines using a tetrazolium-based colorimetric assay
    • Park J.G., Kramer B.S., Steinberg S.M., Carmichael J., Collins J.M., Minna J.D., Gazdar A.F. Chemosensitivity testing of human colorectal carcinoma cell lines using a tetrazolium-based colorimetric assay. Cancer Res. 47:1987;5875-5879.
    • (1987) Cancer Res. , vol.47 , pp. 5875-5879
    • Park, J.G.1    Kramer, B.S.2    Steinberg, S.M.3    Carmichael, J.4    Collins, J.M.5    Minna, J.D.6    Gazdar, A.F.7
  • 23
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 24
    • 0025347423 scopus 로고
    • Determination of plasma free fatty acids, free cholesterol, cholesteryl esters, and triacylglycerols directly from total lipid extract by capillary gas chromatography
    • Lohninger A., Preis P., Linhart L., Sommoggy S.V., Landau M., Kaiser E. Determination of plasma free fatty acids, free cholesterol, cholesteryl esters, and triacylglycerols directly from total lipid extract by capillary gas chromatography. Anal. Biochem. 186:1990;243-250.
    • (1990) Anal. Biochem. , vol.186 , pp. 243-250
    • Lohninger, A.1    Preis, P.2    Linhart, L.3    Sommoggy, S.V.4    Landau, M.5    Kaiser, E.6
  • 25
    • 0034972044 scopus 로고    scopus 로고
    • Peroxisomal deficiencies are associated with altered activity of endothelial NOS in human fibroblasts
    • Koeck T., Kremser K. Peroxisomal deficiencies are associated with altered activity of endothelial NOS in human fibroblasts. Nitric Oxide Biol. Ch. 5:2001;213-218.
    • (2001) Nitric Oxide Biol. Ch. , vol.5 , pp. 213-218
    • Koeck, T.1    Kremser, K.2
  • 26
    • 0035018871 scopus 로고    scopus 로고
    • Cellular regulation of endothelial nitric oxide synthase
    • Govers R., Rabelink T.J. Cellular regulation of endothelial nitric oxide synthase. Am. J. Physiol. Renal Physiol. 280:2001;F193-F206.
    • (2001) Am. J. Physiol. Renal Physiol. , vol.280
    • Govers, R.1    Rabelink, T.J.2
  • 28
    • 0035863011 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain-dependent generation of superoxide anion and release into the intermembrane space
    • Han D., Williams E., Cadenas E. Mitochondrial respiratory chain-dependent generation of superoxide anion and release into the intermembrane space. Biochem. J. 353:2001;411-416.
    • (2001) Biochem. J. , vol.353 , pp. 411-416
    • Han, D.1    Williams, E.2    Cadenas, E.3
  • 29
    • 0016821832 scopus 로고
    • Subcellular localisation of superoxide dismutase in rat liver
    • Peeters-Joris C., Vandevoorde A.M., Baudhuin P. Subcellular localisation of superoxide dismutase in rat liver. Biochem. J. 150:1975;31-39.
    • (1975) Biochem. J. , vol.150 , pp. 31-39
    • Peeters-Joris, C.1    Vandevoorde, A.M.2    Baudhuin, P.3
  • 30
    • 0014943206 scopus 로고
    • The cellular localisation of glutathione peroxidase and its release from mitochondria during swelling
    • Green R.C., O'Brien P.J. The cellular localisation of glutathione peroxidase and its release from mitochondria during swelling. Biochim. Biophys. Acta. 197:1970;31-39.
    • (1970) Biochim. Biophys. Acta , vol.197 , pp. 31-39
    • Green, R.C.1    O'Brien, P.J.2
  • 31
    • 0034674055 scopus 로고    scopus 로고
    • 2 gradients across biomembranes
    • 2 gradients across biomembranes. FEBS Lett. 475:2000;121-126.
    • (2000) FEBS Lett. , vol.475 , pp. 121-126
    • Antunes, F.1    Cadenas, E.2
  • 32
    • 0025073266 scopus 로고
    • Modulation of fibroblast proliferation by oxygen free radicals
    • Murrell G.A., Francis M.J., Bromley L. Modulation of fibroblast proliferation by oxygen free radicals. Biochem. J. 265:1990;659-665.
    • (1990) Biochem. J. , vol.265 , pp. 659-665
    • Murrell, G.A.1    Francis, M.J.2    Bromley, L.3
  • 33
    • 0032694302 scopus 로고    scopus 로고
    • The broad spectrum of response to oxidants in proliferating cells: A new paradigm for oxidative stress
    • Davies K.J. The broad spectrum of response to oxidants in proliferating cells: a new paradigm for oxidative stress. IUBMB Life. 48:1999;41-47.
    • (1999) IUBMB Life , vol.48 , pp. 41-47
    • Davies, K.J.1
  • 34
    • 0033952940 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide
    • Drummond G.R., Cai H., Davis M.E., Ramasamy S., Harrison D.G. Transcriptional and post-transcriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ. Res. 86:2000;347-354.
    • (2000) Circ. Res. , vol.86 , pp. 347-354
    • Drummond, G.R.1    Cai, H.2    Davis, M.E.3    Ramasamy, S.4    Harrison, D.G.5
  • 35
    • 0029910141 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1
    • Garcia-Cardena G., Fan R., Stern D.F., Liu J., Sessa W.C. Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. J. Biol. Chem. 271:1996;27237-27240.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27237-27240
    • Garcia-Cardena, G.1    Fan, R.2    Stern, D.F.3    Liu, J.4    Sessa, W.C.5
  • 36
    • 0029955451 scopus 로고    scopus 로고
    • Activation of protein phosphorylation by oxidants in vascular endothelial cells: Identification of tyrosine phosphorylation of caveolin
    • Vepa S., Scribner W.M., Natarajan V. Activation of protein phosphorylation by oxidants in vascular endothelial cells: identification of tyrosine phosphorylation of caveolin. Free Radic. Biol. Med. 22:1997;25-35.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 25-35
    • Vepa, S.1    Scribner, W.M.2    Natarajan, V.3
  • 37
    • 0028824722 scopus 로고
    • Thiol dependence of nitric oxide synthase
    • Hofmann H., Schmidt H.H. Thiol dependence of nitric oxide synthase. Biochemistry. 34:1995;13443-13452.
    • (1995) Biochemistry , vol.34 , pp. 13443-13452
    • Hofmann, H.1    Schmidt, H.H.2
  • 38
    • 0020480049 scopus 로고
    • Malonyl-CoA inhibition of carnitine acyltransferase activities: Effects of thiol-group reagents
    • Saggerson E.D., Carpenter C.A. Malonyl-CoA inhibition of carnitine acyltransferase activities: effects of thiol-group reagents. FEBS Lett. 137:1982;124-128.
    • (1982) FEBS Lett. , vol.137 , pp. 124-128
    • Saggerson, E.D.1    Carpenter, C.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.