Decrease in fibrin content of venous thrombi in selectin-deficient mice

Journal of Surgical Research

Volumn 109, Issue 1, 2003, Pages 1-7

  Sullivan, V V ^a,b   Hawley, A E ^a   Farris, D M ^a   Knipp, B S ^a   Varga, A J ^a   Wrobleski, S K ^a   Thanapron, P ^a   Eagleton, M J ^a   Myers Jr , D D ^a   Fowlkes, J B ^a   Wakefield, T W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Fibrin; Interleukin 10; Knockout mice; Selectins; Venous thrombosis

Indexed keywords

ANTIBODY; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FIBRIN; INTERLEUKIN 10; PADGEM PROTEIN;

ANALYSIS OF VARIANCE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCULATION; CONTROLLED STUDY; INFERIOR CAVA VEIN; KNOCKOUT MOUSE; MOUSE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; STAINING; SURGICAL TECHNIQUE; VEIN LIGATION; VEIN THROMBOSIS;

EID: 0037288534     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-4804(02)00041-0     Document Type: Article

References (26)

1. Downing L.J., Strieter R.M., Kadell A.M., et al. IL-10 regulates thrombus-induced vein wall inflammation and thrombosis. J. Immunol. 161:1998;1471.
2. Henke P.K., DeBrunye L.A., Strieter R.M., et al. Viral IL-10 gene transfer decreases inflammation and cell adhesion molecule expression in a rat model of venous thrombosis. J. Immunol. 164:2000;2131.
3. Downing L.J., Wakefield T.W., Strieter R.M., et al. Anti-P-selectin antibody decreases inflammation and thrombus formation in venous thrombosis. J. Vasc. Surg. 25:1997;816. discussion 828.
4. Wakefield T.W., Strieter R.M., Schaub R., et al. Venous thrombosis prophylaxis by inflammatory inhibition without anticoagulation therapy. J. Vasc. Surg. 31:2000;309.
5. Myers D.D. Jr, Schaub R., Wrobleski S.K., et al. P-selectin antagonism causes dose-dependent venous thrombosis inhibition. Thromb. Haemost. 85:2001;423.
6. Kumar A., Villani M.P., Patel U.K., Keith J.C., Schaub R.G. Jr. Recombinant soluble form of PSGL-1 accelerates thrombolysis and prevents reocclusion in a porcine model. Circulation. 99:1999;1363.
7. Zhang H., Schaub R.G., Keith J.C. Jr, Kumar A. Recombinant soluble P-selectin glycoprotein ligand chimera has a thrombolytic effect in a rat model of thrombosis. J. Am. Coll. Cardiol. 35:2000;280.
8. Toombs C.F., DeGraaf G.L., Martin J.P., Geng J.G., Anderson D.C., Shebuski R.J. Pretreatment with a blocking monoclonal antibody to P-selectin accelerates pharmacological thrombolysis in a primate model of arterial thrombosis. J. Pharmacol. Exp. Ther. 275:1995;941.
9. Myers D.D., Wrobleski S.K., Londy F., et al. New and effective treatment of experimentally induced venous thrombosis with anti-inflammatory rPSGL-Ig. Thromb. Haemost. 87:2002;374.
10. Bullard D.C., Kunkel E.J., Kubo H., et al. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J. Exp. Med. 183:1996;2329.
11. Bullard D.C., Qin L., Lorenzo I., et al. P-selectin/ICAM-1 double mutant mice: Acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli. J. Clin. Invest. 95:1995;1782.
12. Myers, D., Farris, D., Hawley, A., et al. Selectins influence thrombus in a mouse model of experimental DVT. J. Surg Res. (in press).
13. Kuhn R., Lohler J., Rennick D., Rajewsky K., Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 75:1993;263.
14. Myers D.D., Wrobleski S.K., Henke P.K., Wakefield T.W. Coagulation Biology. Souba W.W., Wilmore D.W. Surgical Research. 2001;989-1000 Academic Press, San Diego.
15. Libby P., Simon D.I. Inflammation and thrombosis The clot thickens . Circulation. 103:2001;1718.
16. Matsuo T., Mori H., Nishimura Y., Maeda T., Nakagawa J.I., Obashi A. Quantification of immunohistochemistry using an image analyser Correlation with hormone concentrations in pituitary adenomas . Histochem. J. 27:1995;989.
17. Andre P., Hartwell D., Hrachovinova I., Saffaripour S., Wagner D.D. Pro-coagulant state resulting from high levels of soluble P-selectin in blood. Proc. Natl. Acad. Sci. USA. 97:2000;13835.
18. Furie B., Furie B.C., Flaumenhaft R. A journey with platelet P-selectin The molecular basis of granule secretion, signalling and cell adhesion . Thromb. Haemost. 86:2001;214.
19. Palabrica T., Lobb R., Furie B.C., et al. Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature. 359:1992;848.
20. Rauch U., Bonderman D., Bohrmann B., et al. Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. Blood. 96:2000;170.
21. Wakefield T.W., Strieter R.M., Downing L.J., et al. P-selectin and TNF inhibition reduce venous thrombosis inflammation. J. Surg. Res. 64:1996;26.
22. Satta N., Toti F., Feugeas O., et al. Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharide. J. Immunol. 153:1994;3245.
23. Mesri M., Altieri D.C. Leukocyte microparticles stimulate endothelial cell cytokine release and tissue factor induction in a JNK1 signaling pathway. J. Biol. Chem. 274:1999;23111.
24. Kirchhofer D., Tschopp T.B., Steiner B., Baumgartner H.R. Role of collagen-adherent platelets in mediating fibrin formation in flowing whole blood. Blood. 86:1995;3815.
25. Giesen P.L., Rauch U., Bohrmann B., et al. Blood-borne tissue factor Another view of thrombosis . Proc. Natl. Acad. Sci. USA. 96:1999;2311.
26. Swords N.A., Tracy P.B., Mann K.G. Intact platelet membranes, not platelet-released microvesicles, support the procoagulant activity of adherent platelets. Arterioscler. Thromb. 13:1993;1613.