Dietary cadmium inhibits spontaneous hepatocarcinogenesis in C3H/HeN mice and hepatitis in A/J mice, but not in C57BL/6 mice

Toxicology and Applied Pharmacology

Volumn 186, Issue 1, 2003, Pages 1-6

  Nishiyama, Shoji ^a,e   Itoh, Norio ^b   Onosaka, Satomi ^c   Okudaira, Masahiko ^d   Yamamoto, Hiroshi ^b   Tanaka, Keiichi ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KOBE GAKUIN UNIVERSITY   (Japan)

^d KITASATO UNIVERSITY   (Japan)

^e MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

Anticarcinogenesis; Cadmium; Metallothionein; Zinc

Indexed keywords

CADMIUM; CARCINOGEN; METAL; MUTAGENIC AGENT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; HEPATITIS; LIVER CARCINOGENESIS; LIVER DISEASE; LIVER LEVEL; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN SYNTHESIS;

ANIMALIA;

EID: 0037288248     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(02)00029-7     Document Type: Article

References (23)

1. Altam P.L., Katz D.D. Tumors. Altam P.L., Katz D.D. Inbred and Genetically Defined Strains of Laboratory Animals, Part 1. 1979;157-212 Federation of American Societies for Experimental Biology, Bethesda, MD.
2. Cherian M.G., Howell S.B., Imura N., Klaassen C.D., Koropatnick J., Lazo J.S., Waalkes M.P. Role of metallothionein in carcinogenesis. Toxicol. Appl. Pharmacol. 126:1994;1-5.
3. Cousins R.J., Leinart A.S. Tissue-specific regulation of zinc metabolism and metallothionein genes by interleukin 1. FASEB J. 2:1988;2884-2890.
4. Danielson K.G., Ohi S., Huang P.C. Immunochemical detection of metallothionein in specific epithelial cells of rat organs. Proc. Natl. Acad. Sci. USA. 79:1982;2301-2304.
5. Goncharova E.I., Rossman T.G. A role for metallothionein and zinc in spontaneous mutagenesis. Cancer Res. 54:1994;5318-5323.
6. Kägi J.H.R., Kojima Y. Chemistry and biochemistry of metallothionein. Kägi J.H.R. Metallothionein II. 1987;196-266 Birkhauser Verlag, Basel.
7. Karin M. Metallothioneins proteins in search of function . Cell. 41:1985;9-10.
8. Lee J.S., White K.L. A review of the health effects of cadmium. Am. J. Ind. Med. 1:1980;307-317.
9. Maronpot R.R., Montgomery C.A., Boorman G.A., McConnell E.E. National Toxicology Program nomenclature for hepatoproliferative lesions of rats. Toxicol. Pathol. 14:1986;263-273.
10. Nishiyama S., Saito N., Konishi Y., Abe Y., Kusumi K. Cardiotoxicity in magnesium-deficient rats fed cadmium. J. Nutr. Sci. Vitaminol. (Tokyo). 36:1990;33-44.
11. Onosaka S., Min K.S., Fukuhara C., Tanaka K., Tashiro S., Shimizu I., Furuta M., Yasutomi T., Kobashi K., Yamamoto K. Concentrations of metallothionein and metals in malignant and non-malignant tissues in human liver. Toxicology. 38:1986;261-268.
12. Piscator M. Role of cadmium in carcinogenesis with special reference to cancer of the prostate. Environ. Health Perspect. 40:1981;107-120.
13. Rossman T.G., Goncharova E.I. Spontaneous mutagenesis in mammalian cells is caused mainly by oxidative events and can be blocked by antioxidants and metallothionein. Mutat. Res. 402:1998;103-110.
14. Rossman T.G., Goncharova E.I., Nadas A., Dolzhanskaya N. Chinese hamster cells expressing antisense to metallothionein become spontaneous mutators. Mutat. Res. 373:1997;75-85.
15. Ruth S.M. The role of zinc in growth and cell proliferation. J. Nutr. 130:2000;1500S-1508S.
16. Sakurai, H., 1978. Occupational exposure, in: Tsuchiya, K. (Ed.), Cadmium Studies in Japan: A Review, Kodansha Ltd., Tokyo, and Elsevier/North Holland Biomedical Press, Amsterdam, pp. 133-144.
17. Tamano H., Igasaki E., Enomoto S., Oku N., Itoh N., Kimura T., Tanaka K., Takeda A. Hepatic zinc response via metallothionein induction after tumor transplantation. Biochem. Biophys. Res. Commun. 270:2000;1140-1143.
18. Thomas J.P., Bachowski G.J., Girotti A.W. Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothioneins. Biochim. Biophys. Acta. 884:1986;448-461.
19. Thornalley P.J., Vasak M. Possible role for metallothionein in protection against radiation-induced oxidative stress kinetics and mechanism of its reaction with superoxide and hydroxyl radicals . Biochim. Biophys. Acta. 827:1985;36-44.
20. Tsuchiya, K., 1978. History of itai-itai disease, in: Tsuchiya, K. (Ed.), Cadmium Studies in Japan: A Review, Kodansha Ltd., Tokyo, and Elsevier/North Holland Biomedical Press, Amsterdam, pp. 1-5.
21. Waalkes M.P., Diwan B.A., Weghorst C.M., Bare R.M., Ward J.M., Rice J.M. Anticarcinogenic effects of cadmium in B6C3F1 mouse liver and lung. Toxicol. Appl. Pharmacol. 110:1991;327-335.
22. Waalkes M.P., Diwan B.A., Weghorst C.M., Ward J.M., Rice J.M., Cherian M.G., Goyer R.A. Further evidence of the tumor-suppressive effects of cadmium in the B6C3F1 mouse liver and lung late stage vulnerability of tumors to cadmium and the role of metallothionein . J. Pharmacol. Exp. Ther. 266:1993;1656-1663.
23. Wu F.Y., Wu C.W. Zinc in DNA replication and transcription. Ann. Rev. Nutr. 7:1987;251-272.