Renal function in adult rats subjected to prenatal dexamethasone

Clinical and Experimental Pharmacology and Physiology

Volumn 30, Issue 1-2, 2003, Pages 32-37

  Martins, João P C ^a   Monteiro, Josélia C ^a   Paixão, Ana D O ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Dexamethasone; Fetal development; Nephrons; Prenatal glucocorticoids; Renal haemodynamics

Indexed keywords

DEXAMETHASONE; INULIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS DEVELOPMENT; GLOMERULUS FILTRATION RATE; HEMODYNAMICS; HYPERTENSION; INULIN CLEARANCE; KIDNEY BLOOD FLOW; KIDNEY DEVELOPMENT; KIDNEY FUNCTION; KIDNEY TUMOR; KIDNEY VASCULAR RESISTANCE; LOW BIRTH WEIGHT; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; ORGANOGENESIS; PRENATAL DRUG EXPOSURE; PROTEIN DIET; RAT; WEIGHT GAIN;

EID: 0037283218     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2003.03787.x     Document Type: Article

References (34)

1. Bian X, Seidler FJ, Slotkin A. Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity. Teratology 1993; 47: 109-17.
2. Reinisch JM, Simon NG, Karow WG, Gandelman R. Prenatal exposure to prednisone in humans and animals retards intrauterine growth. Science 1978; 202: 436-8.
3. Celsi G, Kistner A, Aizman R et al. Prenatal dexamethasone causes oligonephronia, sodium retention, and higher blood pressure in offspring. Pediatr. Res. 1998; 44: 317-22.
4. Ortiz LA, Quan A, Weinberg A, Baum M. Effect of prenatal dexamethasone on rat renal development. Kidney Int. 2001; 59: 1663-9.
5. Woods LL, Weeks DA, Rasch R. Hypertension after neonatal uninephrectomy in rats precedes glomerular damage. Hypertension 2001; 38: 337-42.
6. Paixão AD, Maciel CR, Teles MBB, Figueiredo-Silva J. Regional Brazilian diet induced low birth weight is correlated with changes in renal hemodynamics and glomerular morphometry in adult age. Biol. Neonate 2001; 80: 239-46.
7. Woods LL, Rasch R. Perinatal ANGII programs adult blood pressure, glomerular number, and renal functions in rats. Am. J. Physiol. 1998; 275: R1593-9.
8. Hostetter TH, Meyer TW, Rennke HG, Brenner BM. Chronic effects of dietary protein in the rat with intact and reduced renal mass. Kidney Int. 1986; 30: 509-17.
9. Reyes AA, Klahr S. Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet. Proc. Soc. Exp. Biol. Med. 1994; 206: 157-61.
10. Speller AM, Moffat DB. Tubulo-vascular relationships in the developing kidney. J. Anat. 1977; 123: 487-500.
11. Tufro-McReddie A, Romano LM, Harris JM, Ferder L, Gomez RA. Angiotensin II regulates nephrogenesis and renal vascular development. Am. J. Physiol. 1995; 269: F110-15.
12. Howard-Jones N. A CIOMS ethical code for animal experimentation. WHO Chronicle 1985; 39: 51-6.
13. Maddox DA, Price DC, Rector Jr FC. Effects of surgery on plasma volume and salt and water excretion in rats. Am. J. Physiol. 1977; 233: F600-6.
14. Ichikawa I, Maddox DA, Cogan MG, Brenner B. Dynamics of glomerular ultrafiltration in euvolemic Munich Wistar rats. Renal Physiol. 1978; 1: 121-31.
15. Paixão AD, Ferreira AT, Oshiro MEM, Razviczas CV, Boim MA, Schor N. Renal hemodynamic response to erythropoietin-induced polycythemia in 5/6 nephrectomised rats is different from normal rats. Exp. Nephrol. 1998; 6: 245-52.
16. Wilcox CS, Deng X, Doll AH, Snellen H, Welch WJ. Nitric oxide mediates renal vasodilatation during erythropoietin-induced polycythemia. Kidney Int. 1993; 44: 430-5.
17. Fuhr J, Kaczmarczyk J, Kruttgen CD. Eine einfache colorimetrische Method zur Inulinbestimmung fur Nierenclearanceunter-suchungen bei Stoffwechselgesunden und Diabetikern. Klin. Wochenschr. 1955; 33: 729-30.
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951; 193: 265-75.
19. Larsson L, Aperia A, Wilton P. Effect of normal development on compensatory renal growth. Kidney Int. 1980; 18: 29-35.
20. Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CRW. Glucocorticoid exposure in utero: New model for adult hypertension. Lancet 1993; 341: 339-41.
21. Holness MJ, Sugden MC. Dexamethasone during late gestation exacerbates peripheral insulin resistance and selectively targets glucose-sensitive functions in beta cell and liver. Endocrinology 2001; 142: 3742-8.
22. Langley-Evans SC, Welhman SJM, Jackson AA. Fetal exposure to a maternal low protein diet impairs nephrogenesis and promotes hypertension in the rat. Life Sci. 1999; 64: 965-74.
23. Bertram JF, Soosaipillai MC, Ricardo SD, Ryan GB. Total numbers of glomeruli and individual glomerular cell types in the normal rat kidney. Cell Tissue Res. 1992; 270: 37-45.
24. Brenner BM, Garcia DL, Anderson S. Glomeruli and blood pressure. Less of one, more the other? Am. Hypertens. 1988; 1: 335-47.
25. Meaney MJ, Aitken DH, Viau V, Sharma S, Sarrieau A. Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor biding in the rat. Neuroendocrinology 1989; 50: 597-604.
26. Plotsky PM, Meaney MJ. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Mol. Brain Res. 1993; 18: 195-200.
27. Matsukawa K, Ninomiya I, Nishiura N. Effects of anesthesia on cardiac and renal sympathetic nerve activities and plasma catecholamines. Am. J. Physiol. 1993; 265: R792-7.
28. Sheuer DA, Mifflin SW. Glucocorticoids modulate baroreflex control of renal sympathetic nerve activity. Am. J. Physiol. 2001; 280: R1440-9.
29. Lemley KV. Glomerular size selectivity during protein overload in the rat. Am. J. Physiol. 1993; 264: F1046-51.
30. Nyirenda MJ, Lindsay RS, Kenyon CJ, Burchell A, Seckl JR. Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring. J. Clin. Invest. 1998; 101: 2174-81.
31. Hadid R, Spinedi E, Chautard T, Giacomini M, Gaillard RC. Role of several mediators of inflammation on the mouse hypothalamo-pituitary-adrenal axis response during acute endotoxemia. Neuroimmunomodulation 1999; 6: 336-43.
32. Nilsson C, Larsson BM, Jennische E, Eriksson E, Bjorntorp P, York DA. Maternal endotoxemia results in obesity and insulin resistance in adult male offspring. Endocrinology 2001; 142: 2622-30.
33. Aird F, Halasz I, Redei E. Ontogeny of hypothalamic cortictropin-releasing factor and anterior pituitary pro-opiomelanocortin expression in male and female offspring of alcohol-exposed and adrenalectomized dams. Alcohol Clin. Exp. Res. 1997; 21: 1560-6.
34. Langley-Evans SC. Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis. J. Hypertens. 1997; 15: 537-44.