Pharmacokinetics and metabolism of radiolabelled SNI-2011, a novel muscarinic receptor agonist, in healthy volunteers: Comprehensive understanding of absorption, metabolism and excretion using radiolabelled SNI-2011

Arzneimittel-Forschung/Drug Research

Volumn 53, Issue 2, 2003, Pages 80-86

  Washio, Takuo ^a   Kohsaka, Kazuhiro ^a   Arisawa, Hirohiko ^a   Masunaga, Hiroaki ^a   Nagatsuka, Shin Ichiro ^b   Satoh, Yoshiaki ^b  

^a SNOW BRAND MILK PRODUCTS CO LTD   (Japan)

^b DAIICHI PURE CHEMICALS CO LTD   (Japan)

Author keywords

CAS 153504 70 2; Cevimeline; Muscarinic receptor agonist; SNI 2011, clinical studies, metabolism, pharmacokinetics

Indexed keywords

CARBON 14; CEVIMELINE; CEVIMELINE C 14; CEVIMELINE GLUCURONIDE; CEVIMELINE N OXIDE; CEVIMELINE SULFOXIDE; DRUG METABOLITE; MUSCARINIC AGENT; SN 2011; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG SAFETY; DRUG TOLERABILITY; HUMAN; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NORMAL HUMAN; RADIOACTIVITY; SIDE EFFECT; URINALYSIS; URINARY EXCRETION;

EID: 0037283215     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1297076     Document Type: Article

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