Biochemical enzyme activity in different tissues of rats exposed to a novel phosphorothionate (RPR-V)

Journal of Environmental Science and Health - Part B Pesticides, Food Contaminants, and Agricultural Wastes

Volumn 38, Issue 1, 2003, Pages 59-71

  Rahman, Mohammed F ^a   Siddiqui, Mohammed K J ^b  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Acetylcholinesterase; Alanine aminotransferase; Aspartate aminotransferase; Phosphorothionate; Rat

Indexed keywords

BIOCHEMISTRY; BIOMARKERS; ENZYMES; TISSUE;

BIOMARKER ENZYMES;

PESTICIDE EFFECTS;

ACETYLCHOLINESTERASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; ENZYME; ORGANOPHOSPHATE INSECTICIDE; PHOSPHOROTHIONATE; RPR V; UNCLASSIFIED DRUG;

ENZYME; POLLUTION EXPOSURE; RODENT;

ADAPTATION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; KIDNEY; LIVER; LONG TERM EXPOSURE; LUNG; MALE; NONHUMAN; RAT; SERUM; SEX DIFFERENCE; SYNAPTIC TRANSMISSION; TISSUE NECROSIS;

ACETYLCHOLINESTERASE; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INSECTICIDES; KIDNEY; LETHAL DOSE 50; LIVER; LUNG; MALE; MONOCROTOPHOS; ORGANOTHIOPHOSPHORUS COMPOUNDS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SEX CHARACTERISTICS; SULFHYDRYL COMPOUNDS;

ANIMALIA; RODENTIA;

EID: 0037278099     PISSN: 03601234     EISSN: None     Source Type: Journal    
DOI: 10.1081/PFC-120016606     Document Type: Article

References (28)

1. Chen, W.L.; Sheets, J.J.; Nolan, R.J.; Mattsson, J.L. Human red blood cell acetylcholinesterase inhibition as the appropriate and conservative surrogate end point for establishing chloropyrifos reference dose. Regul. Toxicol. Pharmacol. 1999, 29, 15-22.
2. Siddiqui, M.K.J.; Rahman, M.F.; Mustafa, M. Target enzyme inhibition by novel thion analogues of monocrotophos: An acute in vivo study in rat. Bull. Environ. Contam. Toxicol. 1993, 51, 409-415.
3. Rani, R.; Neelkantan, P.; Thyagarajan, G.; Bhalerao, U.T.; Rahman, M.F.; Grover, P.; Khan, M.M.A.; Qadri, S.S.H. The Gazette of India (Indian Patent No. 165259), Process for the manufacture of organophosphorus compounds for combating pests. The Patent Office, Kolkata, India, 1989; 869.
4. Rahman, M.F.; Siddiqui, M.K.J.; Mustafa, M. Effects of a new phosphorothionate (RPR-V) on ATPases and acetylcholinesterase in rat brain by sub-chronic dosing. J. Appl. Toxicol. 1997, 17, 273-278.
5. Khan, I.A.; Reddy, B.V.; Mahboob, M.; Rahman, M.F.; Jamil, K. Effects of phosphorothionate on the reproductive system of male rats. J. Environ. Sci. Health, Part B, Pestic. Food Contam. Agric. Wastes 2001, 36, 445-456.
6. Oluah, N.S. Plasma aspartate aminotransferase activity in the cat fish Clarias albopunctatus exposed to sub-lethal zinc and mercury. Bull. Environ. Contam. Toxicol. 1999, 63, 343-349.
7. Vadekar, M. Minimizing occupational exposure to pesticides: Cholinesterase determination and organophosphorus poisoning. Res. Rev. 1980, 75, 67-80.
8. Jones, R.A.; Badesha, S.S. Phase transfer catalysis: Phosphorylation of β-Dicarbonyl compounds. Syn. Communs. 1981, 11, 557-560.
9. Gaitonde, B.B. The Insecticide Act 1968. In Report of the Sub-Committee on Pesticide Toxicology; Gupta, V.K., Ed.; Geetanjali Publications: New Delhi, 1983; 157-179.
10. Yatzidis, S.H. Measurement of transaminases in serum. Nature 1960, 186, 79-80.
11. Ellman, G.L.; Courtney, K.D.; Anders, R.J.R.; Featherstone, R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 1961, 7, 88-95.
12. Chambers, H.W.; Chambers, J.E. An investigation of acetylcholinesterase inhibition and aging and choline acetyltransferees activity following a high level acute exposure to paraoxon. Pestic. Biochem. Physiol. 1989, 33, 125-131.
13. Lowry, O.H.; Rosebrough, N.J.; Farr., A.L.; Randall, R.J. Protein measurement with folin phenol reagent. J. Biol. Chem. 1951, 193, 265-276.
14. Kaur, H.; Srivastave, A.K.; Garg, S.K.; Prakash, D. Sub-acute oral toxicity of chloropyriphos in goats with pesticides reference to blood biochemical and pathomorphorlogical alterations. Indian J. Toxicol. 2000, 7, 83-90.
15. Janardhan, A.; Sisodia, P. Monocrotophos: Short term toxicity in rats. Bull. Environ. Contam. Toxicol. 1990, 44, 230-239.
16. Rahman, M.F.; Siddiqui, M.K.J.; Jamil, K. Biochemical alterations induced by a new phosphorothionate (RPR-II) in tissues of male and female rats. Indian J. Exp. Biol. 1999, 37, 546-552.
17. Varley, H.; Gowenlock, A.H.; Bell, M. Practical Clinical Biochemistry, 5th Ed.; William Hainemann Medical Books Ltd.: London, 1980; 850-875.
18. Reddy, S.J.; Reddy, B.V.; Ramamurthi, R. Impact of chronic phosalone toxicity on erythropoietic activity of fish Orchromis mossambicus. Biochem. Int. 1991, 25, 547-552.
19. Rao, C.V.; Banerji, S.A. Effect of feeding polychlorinated biphenyl (Aroclor 1260) on hepatic enzymes in rats. Indian J. Exp. Biol. 1990, 28, 149-151.
20. Shakoori, A.R.; Ali, S.S.; Saleem, M.A. Effects of six months feeding of cypermethrin on the blood and liver of albino rats. J. Biochem. Toxicol. 1988, 3, 59-71.
21. Ravinder, P.; Srivasan, K.; Radhakrishnamurthy, R. Biochemical toxicity of HCH and its γ-isomer in albino mice. Indian J. Exp. Biol. 1989, 27, 248-251.
22. Srivastava, A.K.; Raina, R.; Chaudhary, R.K.; Malik, J.K. Acute toxicity and biochemical alterations in rats after single oral exposure to dichlorvos. Pesticides 1989, 2, 35-40.
23. Pardio, V.T.; Ibarra, N.; Rodriguez, M.A. Use of cholinesterase activity in monitoring organophosphate pesticide exposure of cattle produced in tropical areas. J. Agric. Food Chem. 2001, 49, 6057-6062.
24. Machera, K.; Kostakis, E. Anticholinesterase action of a new organophosphate ester diethyl phosphoric ester of the Dicyclopropyloketoxime on wistar rats. Bull. Environ. Contam. Toxicol. 1992, 48, 108-114.
25. Paul, B.S.; Singh, S.D.; Mailik, J.K. Effect of quinalphos on blood enzymes and its acute toxicity in Bubalus bubalus. J. Environ. Sci. Health, Part B, Pestic. Food Contam. Agric. Wastes 1984, 19, 111-122.
26. Awal, M.A.; Malik, J.K. Effects of daily phosphamidon administration on certain blood biochemical measurements in Bubalus bubalis. Bull. Environ. Contam. Toxicol. 1992, 48, 709-714.
27. Jarmillo-Juarez, F.; Posadasdel Rio, F.A.; Reyes, J.L.; Rodriguez, M.L.; Sanchez, E.I.; Cuellar, L.H. Effect of intra uterine exposure to parathion on the activity of renal ATPase in offspring. J. Appl. Toxicol. 1989, 9, 401-405.
28. Ashry, K.M.; Abu-Qare, A.W.; Saleem, F.R.; Hussein, Y.A.; Hamza, S.M.; Kishk, A.M.; Abou-Donia, M.B. Inhibition and recovery of maternal and fetal cholinesterase enzymes following a single oral dose of chlorpyrifos in rats. Arch. Toxicol. 2002, 76, 30-39.