Quinine distribution in mice with Plasmodium berghei malaria

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 28, Issue 1, 2003, Pages 11-20

  Pussard, Eric ^a   Bernier, Alexandra ^a   Fouquet, Elyane ^a   Bouree, Patrice ^a  

^a BICÊTRE HOSPITAL   (France)

Author keywords

Mice; Pharmacokinetics; Plasmodium berghei malaria; Quinine; Tissue distribution

Indexed keywords

QUININE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG MUSCLE LEVEL; DRUG UPTAKE; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALARIA; MALE; MOUSE; NONHUMAN;

EID: 0037276177     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190862     Document Type: Article

References (39)

1. White N.J., Chanthavanich P., Krishna S., Bunch C. and Silamut K. (1983): Quinine disposition kinetics. Br. J. Clin. Pharmacol., 16, 399-403.
2. White N.J., Looareesuwan S., Warrell D.A., Warrell M.J., Bunnag D. and Harinasuta T. (1982): Quinine pharmacokinetics and toxicity in cerebral and uncomplicated falciparum malaria. Am. J. Med., 73, 564-572.
3. Pussard E., Barennes H., Daouda H., Clavier F., Mahaman Sani A., Osse M., Granic G. and Verdier F. (1999): Quinine disposition in globally malnourished children with cerebral malaria. Clin. Pharmacol.Ther., 65, 500-510.
4. Krishna S. and White N.J. (1996): Pharmacokinetics of quinine, chloroquine and amodiaquine: clinical implications. Clin. Pharmacokinet., 30, 263-299.
5. Emudianughe T.S., Bickle Q.D., Taylor M.G. and Andrews B. (1985): Effect of plasmodium berghei infection on benzoic acid metabolism in mice. Experientia, 41, 1407-1409.
6. Mansor S.M., Edwards G., Roberts P.J. and Ward S.A. (1991): The effect of malaria infection on paracetamol disposition in the rat. Biochem. Pharmacol., 41, 1701-1711.
7. Mansor S.M., Ward S.A. and Edwards G. (1991): The effect of malaria infection on antipyrine metabolite formation in the rat. Biochem. Pharmacol., 41, 1264-1266.
8. Wilairatana P., Looareesuwan S., Vanijanonta S., Charoenlarp P. and Wittayalertpanya S. (1994): Hepatic metabolism in severe falciparum malaria: caffeine clearance study. Ann. Trop. Med. Parasitol., 88, 13-19.
9. Mansor S.M., Ward S.A., Edwards G., Hoaksey P.E. and Breckenridge A.M. (1990): The effect of malaria infection on the disposition of quinine and quinidine in the rat isolated perfused liver preparation. J. Pharm. Pharmacol., 42, 428-432.
10. Song G.H., Andre R.G., Scheibel L.W., Wirtz R.A., Cheriathundam E. and Alvares A.P. (1995): Plasmodium berghei: sensitivity of chloroquineresistant and chloroquine-sensitive strains to irradiation and the effect of irradiated parasites on cytochrome P450-dependent monooxygenases. Res. Com. Mol. Path. Pharmacol., 90, 75-85.
11. Saxena N., Saxena A., Dutta G.P., Gatak S. and Pandey V.C. (1987): Effect of Plasmodium yoleii nigeriensis infection and chloroquine on the hepatic mixed function oxidase system of mice. Mol. Biochem. Parasitol., 24, 283-287.
12. Pukrittayakamee S., Looareesuwan S., Keeratithakul D., Davis T.M.E., Teja-Isavadharm P., Nagachinta B., Weber A., Smith A.L., Kyle D. and White N.J. (1997): A study of the factors affecting the metabolic clearance of quinine in malaria. Eur. J. Clin. Pharmacol., 52, 487-493.
13. Silamut K., White N.J., Looareesuwan S. and Warrell D.A. (1985): Binding of quinine to plasma proteins in falciparum malaria. Am. J. Trop. Med. Hyg., 34, 681-686.
14. Peters W. (1987): Chemotherapy and drug resistance in malaria. 2nd Edition. Academic Press. London.
15. Thumwood C.M., Hunt N.H., Clark I.A. and Cowden W.B. (1988): Breakdown of the blood-brain barrier in murine cerebral malaria. Parasitology, 96, 579-589.
16. Brown H., Hien T.T., Day N., Mai N.T., Chuong L.V., Chau T.T., Loc P.P., Phu N.H., Bethell D., Farrar J., Gatter K., White N.J. and Turner G. (1999): Evidence of blood-brain barrier dysfunction in human cerebral malaria. Neuropathol. Appl. Neurobiol., 25, 331-340.
17. Brown H.C., Chau T.T.C., Mai N.T.H., Day N.P.J., Sinh D.X., White N.J., Hien T.T., Farrar J. and Turner G.D.H. (2000): Blood-brain barrier function in cerebral malaria and CNS infections in Vietnam. Neurology, 55, 104-111.
18. Vuong P.N., Richard F., Snounou G., Coquelin F., Rénia L., Gonnet F., Chabaud A.G. and Landau I. (1999): Development of irreversible lesions in the brain, heart and kidney following acute and chronic murine malaria infection. Parasitology, 119, 546-553.
19. Zhao H.J. and Ishizaki T. (1997): The in vitro hepatic metabolism of quinine in mice, rats and dogs: comparison with human liver microsomes. J. Pharmacol. Exp. Ther., 283, 1168-1176.
20. Iliadis A., Brown C. and Huggins M.L. (1992): Apis: a software for model identification, simulation and dosage regimens calculation in clinical and experimental pharmacokinetics. Comp. Methods Programs Biomed., 38, 227-239.
21. Zhang H., Coville P.F., Walker R.J., Miners J.O., Birkett D.J. and Wanwimolruk S. (1997): Evidence for involvement of human CYP3A in the 3-hydroxylation of quinine. Br. J. Clin. Pharmacol.. 43, 245-252.
22. Liddle C., Graham G.G., Christopher R.K., Bhuwapathanapun S. and Duffield A.M. (1981). Identification of new urinary metabolites in man of quinine using methane chemical ionization gas chromatography-mass spectrometry. Xenobiotica, 11, 81-87.
23. Wanwimolruk S., Wong S.M., Zhang H. and Coville P.F. (1996): Simultaneous determination of quinine and a major metabolite 3-hydroxy quinine in biological fluids by HPLC without extraction. J. Liq. Chromatogr., 19, 293-305.
24. Bannon P., Yu P., Cook J.M., Roy L. and Villeneuve J.P. (1998): Identification of quinine metabolites in urine after oral dosing in humans. J. Chromatogr., 715, 387-393.
25. Muller-Eberhard U., Eiseman J.L., Foielart M. and Alvares A.P. (1983): Effect of heme on allylisopropyl acetamide induced changes in heme and drug metabolism in the rhesus monkey (Macaca mulatta). Biochem. Pharmacol., 32, 3763-3769.
26. Bertini R., Bianchi M., Villa P. and Ghezzi P. (1988): Depression of liver drug metabolism and increase in plasma fibrinogen by interleukin 1 and tumor necrosis factor: a comparison with lymphotoxin and interferon. Int. J. Immunopharmacol., 10, 525-530.
27. Monshouwer M., McLellan R.A., Delaporte E., Witkamp R.F., van Miert A. and Renton K.W. (1996): Differential effect of pentoxifylline on lipopolysaccharide-induced downregulation of cytochrome P450. Biochem. Pharmacol., 52, 1195-1200.
28. Pukrittayakamee S., White N.J., Davis T.M., Looareesuwan S., Supanaranond W., Desakorn V., Chaivisuth B. and Williamson D.H. (1992): Hepatic blood flow and metabolism in severe falciparum malaria: clearance of intravenously administered galactose. Clin. Sci., 82, 63-70.
29. Mansor S.M., Molyneux M.E., Taylor T.E., Ward S.A., Wirima J.J. and Edwards G. (1991): Effect of Plasmodium falciparum malaria infection on the plasma concentration of α1-acid glycoprotein and the binding of quinine in Malawian children. Br. J. Clin. Pharmacol., 32, 317-321.
30. Mansor S.M., Ward S.A., Edwards G., Hoakey P.E. and Breckenridge A.M. (1991): The influence of α1-acid Glycoprotein on quinine disposition in the rat isolated perfused liver preparation J. Pharm. Pharmacol., 43, 650-654.
31. Rimchala P., Karbwang J., Sukontason K., Banmairuroi V., Molunto P. and Na-Bangchang K. (1996): Pharmacokinetics of quinine in patients with chronic renal failure. Eur. J. Clin. Pharmacol., 49, 497-501.
32. Ceithami J. and Evans E.A. (1946): The biochemistry of the malaria parasite. VII. In vitro studies of the distribution of quinine between blood cells and their suspending medium. Arch. Biochem. Biophys., 10, 397-416.
33. Salako L.A. and Ajayi F.O. (1987): Distribution and urinary excretion of the desethylmetabolites of chloroquine in the rat. J. Pharm. Pharmacol., 39, 859-860.
34. Mackey L.J., Hochmann A., June C.H., Contreras C.E. and Lambert P.H. (1980): Immunopathological aspects of Plasmodium berghei infection in five strains of mice. II. Immunopathology of cerebral and other tissues lesions during the infection. Clin. Exp. immunol., 42, 412-420.
35. Karbwang J., Davis T.M., Looareesuwan S., Molunto P., Bunnag D. and White N.J. (1993): A comparison of the pharmacokinetic and pharmacodynamic properties of quinine and quinidine in healthy Thai males. Br. J. Clin. Pharmacol., 35, 265-71
36. Rodriguez-Acosta A., Finol H.J., Pulido-Mendez M., Marquez A., Andrade A., Gonzalez N., Aguilar I., Giron M.E. and Pinto A. (1998): Liver ultrastructural pathology in mice infected with Plasmodium berghei. J. Submicrosc. Cytol. Pathol., 30, 299-307.
37. Neill A.L. and Hunt N.H. (1992): Pathology of fatal and resolving Plasmodium berghei cerebral malaria in mice. Parasitology, 105, 165-175.
38. Kusuhara H., Suzuki H., Terasaki T., Kakee A., Lemaire M. and Sugiyama Y. (1997): P-Glycoprotein mediates the efflux of quinidine across the blood-brain barrier. J. Pharmacol. Exp. Ther., 283, 574-580.
39. Fromm M.F. (2000): P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int. J. Clin. Pharmacol. Ther., 38, 69-74.