Determination of time of onset and location of early skeletal lesions in young dogs experimentally infected with Hepatozoon americanum using bone scintigraphy

Veterinary Radiology and Ultrasound

Volumn 44, Issue 1, 2003, Pages 86-91

  Drost, Wm Tod ^a,b   Cummings, Connie A ^a,c   Mathew, J S ^a,d   Panciera, Roger J ^a   Ko, Jeff C H ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c Pathology Associates International   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

99mTc ; Bone scintigraphy; Dog; Hepatozoon americanum; Periosteal reaction; Technetium Tc 99m medronate

Indexed keywords

TECHNETIUM 99M;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE INFECTION; BONE SCINTISCANNING; CARPAL BONE; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL INFECTION; HEPATOZOON AMERICANUM; LONG BONE; NONHUMAN; OOCYST; PARASITE IDENTIFICATION; PATHOGENESIS; PELVIS; PERIOSTEUM; PROTOZOON; SKULL; TARSAL BONE; VERTEBRA; ANIMAL; ANIMAL DISEASE; BONE DISEASE; DOG; DOG DISEASE; FEMALE; MALE; MICROBIOLOGY; SCINTISCANNING; TIME;

ANIMALIA; CANIS FAMILIARIS; HEPATOZOON; HEPATOZOON AMERICANUM; PROTOZOA;

ANIMALS; BONE DISEASES; DOG DISEASES; DOGS; FEMALE; MALE; TIME FACTORS;

EID: 0037268260     PISSN: 10588183     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1740-8261.2003.tb01455.x     Document Type: Article

References (20)

1. Craig TM. Hepatozoonosis. In: Greene CE (ed): Infectious Diseases of the Dog and Cat. Philadelphia, WB Saunders, 1990, p 778-785.
2. Vincent-Johnson NA, Maclntire DK, Baneth G. Canine hepatozoonosis: pathophysiology, diagnosis, and treatment. Comp Cont Edu 1997;19:51-65.
3. Vincent-Johnson NA, MacIntire DK, Lindsay DS, Lenz SD, Baneth G, Shkap V. A new Hepatozoon species from dogs: description of the causative agent of canine hepatozoonosis in North America. J Parasitol 1997;83:1165-1172.
4. MacIntire DK, Vincent-Johnson NA, Dillon AR, Blagburn B, Lindsay DS, Whitley EM, et al. Hepatozoonosis in dogs: 22 cases (1989-1994). J Am Vet Med Assoc 1997;210:916-922.
5. Panciera RJ, Gatto NT, Crystal MA, Helman RG, Ely RW. Canine hepatozoonosis in Oklahoma. J Am Anim Hosp Assoc 1997;33:221-225.
6. Panciera RJ, Ewing SA, Mathew JS, Cummings CA, Kocan AA, Breshears MA, et al. Observations on tissue stages of Hepatozoon amencanum in 19 naturally infected dogs. Vet Parasitol 1998;78:265-276.
7. Barton CL, Russo EA, Craig TM, Green RW. Canine hepatozoonosis: a retrospective study of 15 naturally occurring cases. J Am Anim Hosp Assoc 1985;21:125-134.
8. Craig TM, Smallwood JE, Knauer KW, McGrath JP. Hepatozoon canis infection in dogs: clinical, radiographic, and hematologic findings. J Am Vet Med Assoc 1978;173:967-972.
9. Panciera RJ, Mathew JS, Ewing SA, Cummings CA, Drost WT, Kocan AA. Skeletal lesions of canine Hepatozoonosis caused by Hepatozoon americanum. Vet Path 2000;37:225-230.
10. Heurre MR, Gounon P. Inflammation: patterns and new concepts. Res Immunol 1996;147:417-434.
11. Huffer WE. Morphology and biochemistry of bone remodeling: possible control by vitamin D, parathyroid hormone, and other substances. Lab Inv 1988;59:418-434.
12. Mundy GR. Regulation of bone formation by bone morphogenetic proteins and other growth factors. Clin Ortho Res 1996;323:24-28.
13. Chambers MD. Bone imaging: the diphosphonates. In: Berry CR, Daniel GB (ed): The handbook of veterinary nuclear medicine. Raleigh, North Carolina State University, 1996, p 49-59.
14. Lamb CR. The principles and practice of bone scintigraphy in small animals. Semin Vet Med Surg (Small Anim) 1991;6:140-153.
15. Mathew JS, Ewing SA, Panciera RJ, Woods JP. Experimental transmission of Hepatozoon americanum to dogs by the Gulf Coast tick, Ambylomma maculatum Koch. Vet Parasitol 1998;80:1-14.
16. Ko JCH, Fox SM, Mandsager RE. Sedative and cardiorespiratory effects of medetomidine, medetomidine-butorphanol, and medetomidine-ketamine in dogs. J Am Vet Med Assoc 2000;216:1578-1583.
17. Brodey RS. Hypertrophic osteopathy in the dog: a clinicopathologic survey of 60 cases. J Am Vet Med Assoc 1971;159:1242-1256.
18. Lamb CR. Bone scintigraphy in small animals. J Am Vet Med Assoc 1987;191:1616-1622.
19. Venker-van Haagen AJ, Goedegebuure SA, van den Brom WE, Voorhout G. Scintigraphic imaging of osteomyelitic lesions in four dogs. Vet Radiol 1978;19:41-49.
20. Metcalf MR. Preliminary clinical use of combined blood pool and bone phase radionuclide imaging in dogs. Vet Radiol 1985;26:117-122.