Acute delirium, delusion, and depression during IFN-β-1a therapy for multiple sclerosis: A case report

Clinical Neuropharmacology

Volumn 26, Issue 1, 2003, Pages 5-7

  Goeb J L ^a   Cailleau, A ^a   Laine P ^a   Etcharry Bouyx, F ^a   Maugin, D ^a   Duverger, Ph ^a   Gohier, B ^a   Rannou Dubas, K ^a   Dubas, F ^a   Garre J B ^a  

^a ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

Delirium; Delusion; Depression; Interferon 1a; Multiple sclerosis; Side effects

Indexed keywords

ALPHA INTERFERON; ANTIDEPRESSANT AGENT; BETA1A INTERFERON; CORTICOSTEROID; HALOPERIDOL; INTERFERON BETA SERINE; LOXAPINE; METHYLPREDNISOLONE; OXAZEPAM; VENLAFAXINE;

ACUTE DISEASE; ADULT; ARTICLE; CASE REPORT; DELIRIUM; DELUSION; DEMYELINATING DISEASE; DEPRESSION; DISEASE COURSE; DISEASE EXACERBATION; DRUG POTENTIATION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MULTIPLE SCLEROSIS; NEUROLOGIC DISEASE; NEUROPHARMACOLOGY; PRIORITY JOURNAL; PSYCHOSIS; REMISSION;

ADJUVANTS, IMMUNOLOGIC; ADULT; DELIRIUM; DELUSIONS; DEPRESSION; HUMANS; INTERFERON-BETA; MALE; MULTIPLE SCLEROSIS;

EID: 0037262168     PISSN: 03625664     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002826-200301000-00002     Document Type: Article

References (16)

1. Feinstein A, du Boulay G, Ron MA. Psychotic illness in multiple sclerosis. Br J Psychiatry 1992;161:680-5.
2. Garland EJ, Zis AP. Multiple sclerosis and affective disorders. Can J Psychiatry 1991;36:112-7.
3. Heila H, Turpeinen P, Erkinjuntti T. Case study: mania associated with multiple sclerosis. J Am Acad Child Adolesc Psychiatry 1995; 34:1591-5.
4. Borras C, Rio J, Porcel J, et al. Emotional state of patients with relapsing-remitting MS treated with interferon beta-1b. Neurology 1999;52:1636-9.
5. Trask PC, Esper P, Riba M, et al. Psychiatric side effects of interferon therapy: prevalence, proposed mechanisms and future directions. J Clin Oncol 2000;18:2316-26.
6. Dieperink E, Willenbring M, Ho SB. Neuropsychiatric symptoms associated with hepatitis C and interferon alpha: a review. Am J Psychiatry 2000;157:867-76.
7. McDonald EM, Mann AH, Thomas HC. Interferons as mediators of psychiatric morbidity. Lancet 1987;1175-7.
8. Fattovich G, Giustina G, Favarato S, et al. A survey of adverse events in 11 241 patients with chronic viral hepatitis treated with alpha interferon. J Hepatol 1996;24:38-47.
9. Renault PF, Hoofnagie JH, Park Y, et al. Psychiatric complications of long-term interferon Alpha therapy. Arch Intern Med 1987;147:1577-80.
10. Schafer M, Boetsch T, Laakman G. Psychosis in a methadonesubstituted patient during interferon alpha treatment of hepatitis C. Addiction 2000;95:1101-4.
11. Kanno A, Yamada M, Abe M, et al. A case of interferon alphainduced manic psychosis in chronic hepatitis C. Tohoku J Exp Med 1999;187:79-82.
12. Strite D, Valentine AD, Meyers CA. Manic episodes in two patients treated with interferon alpha. J Neuropsychiatry Clin Neurosci 1997;9:273-6.
13. Muraoka H, Sanefuji T, Keida R, et al. A patient with chronic hepatitis C and a history of abuse of analeptic drugs, who showed hallucinations and delusion with interferon administration. Kurume Med J 1996;43:73-7.
14. Kayser N, Louiz H, Guillin O. Syndrome confuso-délirant sous IFN alpha. L'Encéphale 2001;27:585-7.
15. Carpiniello B, Orru MG, Baita A, et al. Mania induced by withdrawal of treatment with interferon alpha. Arch Gen Psychiatry 1998;55:88-9.
16. Van Thiel DH, Friedlander L, Molloy PJ, et al. Interferon alpha can be used successfully in patients with hepatitis C virus-positive chronic hepatitis who have a psychiatric illness. Eur J Gastroenterol Hepatol 1995;7:165-8.