Current understanding of mistletoe lectins

Drug Discovery Today

Volumn 8, Issue 1, 2003, Pages 17-

  Schumacher, Udo ^a   Valentiner, Ursula ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSIDASE; PROTEIN BAX; TELOMERASE; VISCUM ALBUM LECTIN;

APOPTOSIS; CANCER RESEARCH; CYTOPLASM; DRUG ACTIVITY; DRUG MECHANISM; DRUG SPECIFICITY; ENZYME ACTIVITY; ENZYME INHIBITION; INTERNALIZATION; LIPID BILAYER; MOLECULAR WEIGHT; PROTEIN SYNTHESIS; RIBOSOME; ROUGH ENDOPLASMIC RETICULUM; SHORT SURVEY;

EID: 0037253508     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(02)02548-5     Document Type: Note

References (6)

1. Li S-S. Mistletoe lectins: telomerase inhibitors in alternative cancer therapy. Drug Discov. Today. 7:2002;896-897.
2. Eck J., et al. Cloning of the mistletoe lectin gene and characterization of the recombinant A-chain. Eur. J. Biochem. 264:1999;775-784.
3. Schumacher U., et al. Cell biological and immunopharmacological investigations on the use of mistletoe lectin I (ML-I). Loew D., Rietbrock N. Phytopharmaka II Forschung und klinische Anwendung. 1996;197-204 Steinkopff Verlag, Darmstadt.
4. Park, et al. Isolation and characterization of galactoside specific lectin from Korean mistletoe (Viscum album L, var. Coloratum) with lactose-BSA-Sepharose 4B and changes of lectin conformation. Arch. Pharm. Res. 21:1998;429-435.
5. Barbieri, et al. Ribosome-inactivating proteins from plants. Biochim. Biophys. Acta. 1154:1993;237-282.
6. Lyu S.Y., et al. Korean mistletoe lectin-induced apoptosis in hepatocarcinoma cells is associated with inhibition of telomerase via mitochondrial controlled pathway independent of p53. Arch. Pharm. Res. 25:2002;93-101.