Enhancement of J-ST-segment elevation by the glucose and insulin test in Brugada syndrome

PACE - Pacing and Clinical Electrophysiology

Volumn 26, Issue 1 II, 2003, Pages 332-337

  Nogami, Akihiko ^a   Nakao, Motohiro ^a   Kubota, Shoichi ^a   Sugiyasu, Aiko ^a   Doi, Hiroshi ^a   Yokoyama, Ken ^a   Yumoto, Kazuhiko ^a   Tamaki, Toshiyuki ^a   Kato, Ken Ichi ^a   Hosokawa, Noriyo ^b   Sagai, Hiroshi ^b   Nakamura, Hiroyuki ^c   Nitta, Jun Ichi ^c   Yamauchi, Yasuteru ^d   Aonuma, Kazutaka ^d  

^a YOKOHAMA ROSAI HOSPITAL   (Japan)

^b Hokushin General Hospital   (Japan)

^c MUSASHINO RED CROSS HOSPITAL   (Japan)

^d YOKOSUKA KYOSAI HOSPITAL   (Japan)

Author keywords

Brugada syndrome; Glucose; Insulin; Pilsicainide; Potassium channel; Ventricular fibrillation

Indexed keywords

GLUCOSE; INSULIN; PILSICAINIDE; POTASSIUM;

ADULT; BRUGADA SYNDROME; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONFERENCE PAPER; ECG ABNORMALITY; ELECTROCARDIOGRAPHY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN SENSITIVITY; MALE; POTASSIUM BLOOD LEVEL; ST SEGMENT ELEVATION; SYNCOPE;

EID: 0037247563     PISSN: 01478389     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9592.2003.00044.x     Document Type: Conference Paper

References (17)

1. Antzelevitch C. The Brugada syndrome. J Cardiovasc Electrophysiol 1998; 9:513-516.
2. Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 1999; 100:1660-1666.
3. Miyazaki T, Mitamura H, Miyoshi S, et al. Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome. J Am Coll Cardiol 1996; 27:1061-1070.
4. Kasanuki H, Ohnishi S, Ohtuka M, et al. Idiopathic ventricular fibrillation induced with vagal activity in patients without obvious heart disease. Circulation 1997; 95:2227-2285.
5. Krishnan SC, Josephson ME. ST segment elevation induced by class IC antiarrhythmic agents: Underlying electrophysiologic mechanisms and insights into drug-induced proarrhythmia. J Cardiovasc Electrophysiol 1998; 9:1167-1172.
6. Tada H, Nogami A, Shimizu W, et al. ST segment and T wave alternans in a patient with Brugada syndrome. PACE 2000; 23:413-415.
7. Shimizu W, Antzelevitch C, Suyama K, et al. Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. J Cardiovasc Electrophysiol 2000; 11:1320-1329.
8. Brugada R, Brugada J, Antzelevitch C, et al. Sodium channel blockers identify risk for sudden cardiac death in patients with ST-segment elevation and right bundle branch block but structurally normal heart. Circulation 2000; 101:510-515.
9. Matsuo K, Kurita T, Inagaki M, et al. The circadian pattern of the development of ventricular fibrillation in patients with Brugada syndrome. Eur Heart J 1999; 20:465-470.
10. Matsuo K, Shimizu W, Kurita T, et al. Dynamic changes of 12-lead electrocardiograms in a patient with Brugada syndrome. J Cardiovase Electrophysiol 1998; 9:508-512.
11. Aling M, Wilde A. "Brugada" syndrome: Clinical data and suggested pathophysiological mechanism. Circulation 1999; 99:666-673.
12. 2+ current in rat cardiac myocytes. Cardiovasc Res 1999; 42:113-120.
13. Lomuscio A, Vergani D, Marano L, et al. Effect of glibenclamide on ventricular fibrillation in non-insulin-dependent diabetics with acute myocardial infarction. Coron Artery Dis 1994; 5:767-771.
14. Billman GE, Englert HC, Scholkens BA. HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. Part II: Effects on susceptibility to ventrieular fibrillation induced by myocardialischemia in conscious dog. Pharmacology 1998; 286:1465-1473.
15. Dekker JM, Feskens EJ, Schouten EG, et al. QTc duration is associated with levels of insulin and glucose intolerance. The Zutphen elderly study. Diabetes 1996; 45:376-380.
16. Marfella R, Nappo F, De Angelis L, et al. The effect of acute hyperglycemia on QTc duration in healthy man. Diabetologia 2000; 43:571-575.
17. Nishizaki M, Ashikawa T, Yamakawa N, et al. Effects of glucose-induced insulin secretion on ventricular repolarization in patients with congenital long QT syndrome. Circ J 2002; 66:35-40.