Effects of a direct injection of liposoluble iron into rat striatum. Importance of the rate of iron delivery to cells

Free Radical Research

Volumn 37, Issue 1, 2003, Pages 59-67

  Demougeot, C ^a,b   Methy D ^a   Prigent Tessier, A ^a   Garnier, P ^a   Bertrand, N ^a   Guilland, J C ^a   Beley, A ^a   Marie, C ^a  

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

Author keywords

Glial activation; Hydroxyl radical; Iron; Ischemia; Neurodegeneration; Salicylate hydroxylation

Indexed keywords

FERRIC AMMONIUM CITRATE; HYDROXYL RADICAL; IRON; IRON COMPLEX; QUINOLINOL DERIVATIVE; SALICYLIC ACID;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN DISEASE; BRAIN INJURY; CELL TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORPUS STRIATUM; IN VITRO STUDY; IN VIVO STUDY; IRON KINETICS; IRON OVERLOAD; IRON STORAGE; IRON TRANSPORT; LIPID PEROXIDATION; LIPID SOLUBILITY; MALE; MICRODIALYSIS; NONHUMAN; PH; RAT; REVIEW; TISSUE LEVEL;

ANIMALS; APOMORPHINE; CELL DEATH; CELLS, CULTURED; CORPUS STRIATUM; ENDOTHELIUM, VASCULAR; FERRIC COMPOUNDS; HYDROXYL RADICAL; HYDROXYQUINOLINES; INJECTIONS; IRON; LIPID PEROXIDATION; MALE; RATS; RATS, WISTAR; SOLUBILITY;

ANIMALIA;

EID: 0037245308     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/1071576021000033095     Document Type: Review

References (41)

1. Zhan, H., Gupta, R.K., Weaver, J. and Pollack, S. (1990) "Iron bound to low MW ligands: interactions with mitochondria and cytosol", Eur. J. Haematol. 44, 125-131.
2. Ponka, P. (1999) "Cellular iron metabolism", Kidney Int. 55, S2-S11.
3. Sofic, E., Riederer, P., Heinsen, H., Beckman, H., Reynolds, G.P., Hebenstreit, G. and Youdim, M.B.H. (1988) "Increased iron III and total iron content in postmortem substantia nigra in Parkinsonian brains", J. Neural Transm. 74, 199 -205.
4. Dexter, D.T., Carayon, A., Javoy-Agid, F., Agid, Y., Wells, F.R., Daniel, S.E., Lees, A.J., Jenner, P. and Marsden, C.D. (1991) "Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia", Brain 114, 1953-1975.
5. Babcock, M., de Silva, D., Oaks, R., Davis-Kaplan, S., Jiralerspong S., Montermini, L., Pandolfo, M. and Kaplan, J. (1997) "Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin", Science 276, 1709-1712.
6. Bidmon, H.J., Emde, B., Oermann, E., Kubitz, R., Witte, O.W. and Zilles, K. (2001) "Heme oxygenase-1 (HSP-32) and heme oxygenase-2 induction in neurons and glial cells of cerebral regions and its relation to iron accumulation after focal cortical photothrombosis", Exp. Neurol. 168, 1-22.
7. Kondo, Y., Asanuma, M., Nishibayashi, S., Iwata, E. and Ogawa, N. (1997) "Late-onset lipid peroxidation and neuronal cell death following transient forebrain ischemia in rat brain", Brain Res. 772, 37-44.
8. Palmer, C., Menzies, S.L., Roberts, R.L., Pavlick, G. and Connor, J.R. (1999) "Changes in iron histochemistry after hypoxic-ischemic brain injury in the neonatal rat", J. Neurosci. Res. 56, 60-71.
9. Shoham, S. and Youdim, M.B.H. (2000) "Iron involvement in neural damage and microgliosis in models of neurodegenerative diseases", Cell. Mol. Biol. (Noisy-le-Grand) 46, 743-760.
10. Vayenas, D.V., Repanti, M., Vassilopoulos, A. and Papanastasiou, D.A. (1998) "Influence of iron overload on manganese, zinc, and copper concentration in rat tissues in vivo: study of liver, spleen, and brain", Int. J. Clin. Lab. Res. 28, 183-186.
11. Engström, E.R., Hillered, L., Flink, R., Kihlström, L., Lindquist, C., Nie, J.X., Olsson, Y. and Silander, H.C. (2001) "Extracellular amino acid levels measured with intracerebral microdialysis in the model of posttraumatic epilepsy induced by intracortical iron injection", Epilepsy Res. 43, 135-144.
12. Hironishi, M., Ueyama, E. and Senba, E. (1999) "Systematic expression of immediate early genes and intensive astrocyte activation induced by intrastriatal ferrous iron injection", Brain Res. 828, 145-153.
13. Sengstock, G.J., Olanow, C.W., Dunn, A.J. and Arendash, G.W. (1992) "Iron induces degeneration of nigrostriatal neurons", Brain Res. Bull. 28, 645-649.
14. Sengstock, G.J., Zawia, N.H., Olanow, C.W., Dunn, A.J. and Arendash, G.W (1997) "Intranigral iron infusion in the rat. Acute elevations in nigral lipid peroxidation and striatal dopaminergic markers with ensuing nigral degeneration", Biol. Trace Elem. Res. 58, 177-195.
15. Sloot, W.N., van der Sluijs-Gelling, A.J. and Gramsbergen, J.B.P. (1994) "Selective lesions by manganese and extensive damage by iron injection into rat striatum or hippocampus", J. Neurochem. 62, 205-216.
16. Willmore, L.J. and Rubin, J.J. (1981) "Antiperoxidant pretreatment and iron-induced epileptiform discharges in the rat: EEG and histopathologic studies", Neurology 31, 63-69.
17. Robinson, T.E. and Whishaw, I.Q. (1998) "Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats", Brain Res. 450, 209-224.
18. Demougeot, C., Marie, C. and Beley, A. (2000) "Importance of iron location in iron-induced hydroxyl radical production by brain slices", Life Sci. 67, 399-410.
19. Zaleska, M.M. and Floyd, R.A. (1985) "Regional lipid peroxidation in rat brain in vitro: possible role of endogenous iron", Neurochem. Res. 10, 397-410.
20. Muruganandam, A., Moorhouse Herx, L., Monette, R., Durkin, J.P. and Stanimirovic, D.B. (1997) "Development of immortalized human cerebromicrovascular endothelial cell line as an in vitro model of the human blood-brain barrier", FASEB J. 11, 1187-1197.
21. Uliasz, T.F. and Hewett, S.J. (2000) "A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture", J. Neurosci. Methods 100, 157-163.
22. Kontoghiorghes, G.J., Piga, A. and Hoffbrand, A.V. (1986) "Cytotoxic and DNA-inhibitory effects of iron chelators on human leukaemic cell lines", Hematol. Oncol. 4, 195-204.
23. Ferreira, C., Bucchini, D., Martin, M.E., Levi, S., Arosio, P., Grandchamp, B. and Beaumont, C. (2000) "Early embryonic lethality of H ferritin gene deletion in mice", J. Biol. Chem. 275, 3021-3024.
24. Rudeck, M., Volk, T., Sitte, N. and Grune, T. (2000) "Ferritin oxidation in vitro: implication of iron release and degradation by the 20S proteasome", IUBMB Life 49, 451-456.
25. Mohanakumar, K.P., Hanbauer, L. and Chiueh, C.C. (1998) "Neuroprotection by nitric oxide against hydroxyl radical-induced nigral neurotoxicity", J. Chem. Neuroanat. 14, 195-205.
26. Ciuffi, M., Gentilini, G., Franchi-Maicheli, S. and Zilletti, L. (1991) "Lipid peroxidation induced in vivo by iron-carbohydrate complex in the rat brain cortex", Neurochem. Res. 16, 43-49.
27. 3 within the ventrolateral striatum causes a chronic disturbance of the integrative function within the limbic part of the ventral striatum", J. Neural Transm. 9, 15-29.
28. Lin, A.M.Y. (2001) "Coexistence of zinc and iron augmented oxidative injuries in the nigrostriatal dopaminergic system of SD rats", Free Radic. Biol. Med. 30, 225-231.
29. + injection", J. Neurochem. 42, 976-980.
30. Heim, C., Kolasiewicz, W. and Sontag, K.H. (2000) "The effects of the 21-aminosteroid U-74389G on spatial orientation in rats after a cerebral oligemic episode and iron-induced oxidative stress", J. Neural Transm. 107, 95-104.
31. Lin, A.M.Y. and Ho, L.W. (2000) "Melatonin suppresses iron-induced neurodegeneration in rat brain", Free Radic. Biol. Med. 28, 904-911.
32. Willmore, L.J. and Rubin, J.J. (1984) "The effect of tocopherol and dimethyl sulfoxide on focal edema and lipid peroxidation induced by isocortical injection of ferrous chloride", Brain Res. 296, 389-392.
33. Oubidar, M., Marie, C., Mossiat, C. and Bralet, J. (1996) "Effects of increasing intracellular reactive iron level on cardiac function and oxidative injury in the isolated rat heart", J. Mol. Cell Cardiol. 28, 1769-1996.
34. Takemura, G., Onodera, T. and Ashraf, M. (1992) "Quantification of hydroxyl radical and its lack of relevance to myocardial injury during early reperfusion after graded ischemia in rat hearts", Circ. Res. 71, 96-105.
35. Huang, X., Dai, J., Fournier, J., Ali, A.M., Zhang, Q. and Frenkel, K. (1984) "Ferrous ion autoxidation and its chelation in iron-loaded human liver HepG2 cells", Free Radic. Biol. Med. 32, 84-92.
36. Pinero, D.J. and Connor, J.R. (2000) "Iron in the brain: an important contributor in normal and diseased states", Neuroscientist 66, 435-453.
37. Soron, F.A. and Ratan, R.R. (2000) "Ironing-out mechanisms of neuronal injury under hypoxic-ischemic conditions and potential role of iron chelators as neuroprotective agents", Antioxid. Redox Signal. 2, 421-435.
38. Qian, Z.M. and Shen, X. (2001) "Brain iron transport and neurodegeneration", Trends Mol. Med. 7, 103-108.
39. Cairo, G. and Pietrangelo, A. (2000) "Iron regulatory proteins in pathobiology", Biochem. J. 352, 241-250.
40. LaVaute, T., Smith, S., Cooperman, S., Iwai, K., Land, W., Meyron-Holtz, E., Drake, S.J., Miller, G., Abu-Asab, M., Tsokos, M., Switzer, III, R., Grinberg, A., Love, P., Tresser, N. and Rouault, T.A. (2001) "Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice", Nat. Genet. 2, 209-214.
41. Oshiro, S., Kawahara, M., Kuroda, Y., Zhang, C., Cai, Y., Kitajima, S. and Shirao, M. (2000) "Glial cells contribute more to iron and aluminium accumulation but are more resistant to oxidative stress than neuronal cells", Biochim. Biophys. Acta 1502, 405-414.