Efficient asymmetric synthesis of β-amino acid BAY 10-8888/PLD-118, a novel antifungal for the treatment of yeast infections

Synthesis

Volumn , Issue 1, 2003, Pages 136-140

  Mittendorf, Joachim ^a   Benet Buchholz, Jordi ^a   Fey, Peter ^a   Mohrs, Klaus Helmut ^a  

^a BAYER AG   (Germany)

Author keywords

Amino acids; Antifungal agents; Asymmetric synthesis; Desymmetrization; Quinine

Indexed keywords

AMINO ACIDS; YEAST;

ASYMMETRIC SYNTHESIS;

SYNTHESIS (CHEMICAL);

2 AMINO 4 METHYLENECYCLOPENTANECARBOXYLIC ACID; BETA AMINO ACID; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; ASYMMETRIC SYNTHESIS; CYCLIZATION; DERIVATIZATION; DRUG EFFICACY; DRUG TOLERABILITY; ENANTIOSELECTIVITY; ESTERIFICATION; HYDROLYSIS; YEAST;

EID: 0037240975     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-36265     Document Type: Article

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