A sensitive test for early myocardial iron loading

European Heart Journal

Volumn 24, Issue 1, 2003, Pages 26-27

  Hoffband, A V ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE; IRON; IRON CHELATE;

CARDIOMYOPATHY; CONFERENCE PAPER; DOPPLER ECHOCARDIOGRAPHY; HEART VENTRICLE SEPTUM; HEART VENTRICLE WALL MOTION; HUMAN; IRON CHELATION; M MODE ECHOCARDIOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT COMPLIANCE; PRIORITY JOURNAL; THALASSEMIA MAJOR;

BETA-THALASSEMIA; CARDIOMYOPATHIES; DEFEROXAMINE; HUMANS; IRON CHELATING AGENTS; IRON OVERLOAD; MAGNETIC RESONANCE IMAGING; SENSITIVITY AND SPECIFICITY;

EID: 0037236870     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-668X(02)00464-5     Document Type: Conference Paper

References (6)

1. Modell B, Khan M, Darlison M. Survival in beta-thalassemia major in the United Kingdom: data from the UK Thalassemia Register. Lancet 2000;355:2051-2.
2. Aldouri MA, Wonke B, Hoffbrand AV et al. High incidence of cardiomyopathy in beta-thalassaemia patients receiving regular transfusion and iron chelation: Reversal by intensified chelation. Acta Haemat 1990;84:113-7.
3. Porter JB. Practical management of iron overload. Br J Haematol 2001;115:239-52.
4. Anderson L, Holden SD, Boris B et al. Cardiovascular T2-start (T2) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001;22:2171-9.
5. Vogel M, Anderson LJ, Holden S et al. Tissue Doppler echocardiography in patients with thalassaemia detects early myocardial dysfunction related to myocardial iron overload. Eur Heart J 2003;23:113-19.
6. Valdez Gruz LM, Reinecke C, Rutkowski M et al. Preclinical abnormal segmental cardiac manifestations of thalassemia major in children on transfusion-chelation therapy: echocardiographic alterations of left ventricular posterior wall contraction and relaxation patterns. Am Heart J 1982; 103:505-11.