Differential regulation of lipopolysaccharide (LPS) activation pathways in mouse macrophages by LPS-binding proteins

Journal of Immunology

Volumn 161, Issue 5, 1998, Pages 2552-2560

  Amura, Claudia R ^a,c   Kamei, Takayuki ^b,d   Ito, Noriko ^a,e   Soares, Michael J ^b   Morrison, David C ^a,b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^d TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BINDING PROTEIN; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; GENETIC TRANSCRIPTION; GRAM NEGATIVE INFECTION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SALMONELLA MINNESOTA; SIGNAL TRANSDUCTION;

ACUTE-PHASE PROTEINS; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOLOGICAL TRANSPORT; BLOOD PROTEINS; CARRIER PROTEINS; CYTOKINES; ENZYME ACTIVATION; FEMALE; KINETICS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C3H; PROTEIN-TYROSINE KINASES; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0032167508     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Morrison, D. C., R. L. Danner, C. A. Dinarello, R. S. Munford, C. Natanson, M. Pollack, J. A. Spitzer, R. J. Ulevitch, S. N. Vogel, and E. McSweegan. 1994. Bacterial endotoxins and pathogenesis of Gram-negative infections: current status and future directions. J. Endotoxin Res. 1:71.
2. Tracey, K. J., and A. Cerami. 1992. Tumor necrosis factor and regulation of metabolism in infection: role of systemic versus tissue levels. Proc. Soc. Exp. Biol. Med. 200:233.
3. Walley, K. R., N. W. Lukacs, R. M. Standford, R. M. Strieter, and S. L. Kunkel. 1996. Balance of inflammatory cytokines related to severity and mortality of murine sepsis. Infect. Immun. 64:4733.
4. Abraham, E., R. Wunderink, H. Silverman, T. M. Perl, S. Nasraway, H. Levy, R. Bone, R. P. Wenzel, R. Balk, R. Allred, J. E. Pemmington, and J. C. Wherry. (TNF-alpha mAb sepsis group). 1997. Efficacy and safety of monoclonal antibodies to tumor necrosis factor alpha in patients with sepsis syndrome: a randomized, controlled, double-blind, multicenter clinical trial. JAMA 273:934.
5. Raetz, C. R., R. J. Ulevitch, S. D. Wright, C. H. Sibley, A. Ding, and C. F. Nathan. 1991. Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction. FASEB J. 5:2652.
6. Sweet, M. J., and D. A. Hume. 1996. Endotoxin signal transduction in macrophages. J. Leukocyte Biol. 60:8.
7. Hailman, E., H. S. Lichenstein, M. M. Wurfel, D. S. Miller, D. A. Johnson, M. Kelley, L. A. Busse, M. M. Zukowski, and S. D. Wright. 1994. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD 14. J. Exp. Med. 179:269.
8. Ulevitch, R. J., and P. S. Tobias. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437.
9. Kirikae, F., T. Kirikae, N. Qureshi, K. Takayama, D. C. Morrison, and M. Nakano. 1995. CD14 is not involved in Rhodobacter sphaeroides diphosphoryl lipid A inhibition of tumor necrosis factor alpha and nitric oxide induction by taxol in murine macrophages. Infect. Immun. 63:486.
10. Lynn, W. A., Y. Liu, and D. T. Golenbock. 1993. Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide. Infect. Immun. 61:4452.
11. Hambleton, J., M. McMahon, and A. L. DeFranco. 1995. Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events. J. Exp. Med. 182:147.
12. Cong, Y. Z., E. Rabin, and H. H. Wortis. 1991. Treatment of murine CD5-B cells with anti-Ig, but not LPS, induces surface CD5: two B-cell activation pathways. Int. Immunol. 3:467.
13. Nitta, T., H. Imai, Y. Ogasawara, and M. Nakano. 1994. Mitogenicity of bacterial lipopolysaccharide on the T lymphocyte population bearing the γδ T cell receptor. J. Endotoxin Res. 1:101.
14. Helfgott, D. C., L. T. May, Z. Sthoeger, I. Tamm, and P. B. Sehgal. 1987. Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts. J. Exp. Med. 166:1300.
15. Frey, E. A., D. S. Miller, T. G. Jahr, A. Sundan, V. Bazil, T. Espevik, B. Finlay, and S. D. Wright. 1992. Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176:1665.
16. Morrison, D. C., M. G. Lei, T. Kirikae, and T. Y. Chen. 1993. Endotoxin receptors on mammalian cells. Immunobiology 187:212.
17. lyn. J. Biol. Chem. 268:20725.
18. Lee, J. C., and P. R. Young. 1996. Role of CSBP/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J. Leukocyte Biol. 59:152.
19. Weinstein, S. L., C. H. June, and A. L. DeFranco. 1993. Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14. J. Immunol. 151:3829.
20. Orlicek, S. L., E. Meals, and B. K. English. 1996. Differential effects of tyrosine kinase inhibitors on tumor necrosis factor and nitric oxide production by murine macrophages. J. Infect. Dis. 174:638.
21. Novogrodsky, A., A. Vanichkin, M. Patya, A. Gazit, N. Osherov, and A. Levitzki. 1994. Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors. Science 264:1319.
22. Kuprash, D. V., I. A. Udalova, R. L. Turetskaya, N. R. Rice, and S. A. Nedospasov. 1995. Conserved kappa B element located downstream of the tumor necrosis factor α gene: distinct NF-κ B binding pattern and enhancer activity in LPS activated murine macrophages. Oncogene 11:97.
23. Murphy, W. J., M. Muroi, C. X. Zhang, T. Suzuki, and S. W. Russell. 1996. Both basal and enhancer κB elements are required for full induction of the mouse inducible nitric oxide synthase gene. J. Endotoxin Res. 3:381.
24. Amura, C. R., L. C. Chen, N. Hirohashi, M. G. Lei, and D. C. Morrison. 1997. Two functionally independent pathways for LPS-dependent activation of mouse peritoneal macrophages. J. Immunol. 159:5079.
25. Schumann, R. R., S. R. Leong, G. W. Flaggs, P. W. Gray, S. D. Wright, J. C. Mathison, P. S. Tobias, and R. J. Ulevitch. 1990. Structure and function of lipopolysaccharide binding protein. Science 249:1429.
26. Gray, P. W., G. Flaggs, S. R. Leong, R. J. Gumina, J. Weiss, C. E. Ooi, and P. Elsbach. 1989. Cloning of the cDNA of a human neutrophil bactericidal protein: structural and functional correlations. J. Biol. Chem. 264:9505.
27. Dentener, M. A., E. J. von Asmuth, G. J. Francot, M. N. Marra, and W. A. Buurman. 1993. Antagonistic effects of lipopolysaccharide binding protein and bactericidal/permeability-increasing protein on lipopolysaccharide-induced cytokine release by mononuclear phagocytes: competition for binding to lipopolysaccharide. J. Immunol. 151:4258.
28. Hirohashi, N., and D. C. Morrison. 1996. Selective effects of serum factors on LPS on bacterial LPS-induced IL-6 and nitric oxide production in murine peritoneal macrophages. J. Endotoxin Res. 3:395.
29. Lorsbach, R. B., W. J. Murphy, C. J. Lowenstein, S. H. Snyder, and S. W. Russell. 1993. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. J. Biol. Chem. 268:1908.
30. Caligan, J. E., A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strobe. 1992. Isolation and analysis of proteins. In Current Protocols in Immunology. S. E. Caligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. Greene Publishing Associates and Wiley Interscience, New York, p. 8.1-8.16.
31. Amura, C. R., P. A. Fontan, N. Sanjuan, M. M. Nociari, F. R. Buzzola, and D. O. Sordelli. 1995. Tumor necrosis factor α plus interleukin 1 β treatment protects granulocytopenic mice from Pseudomonas aeruginosa lung infection: role of an unusual inflammatory response. APMIS 103:447.
32. Muroi, M., Y. Muroi, K. Yamamoto, and T. Suzuki. 1993. Influence of 3′ half-site sequence of NF-κ B motifs on the binding of lipopolysaccharide-activatable macrophage NF-κ B proteins. J. Biol. Chem. 268:19534.
33. Beaty, C. D., T. L. Franklin, Y. Uehara, and C. B. Wilson. 1994. Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction. Eur. J. Immunol. 24: 1278.
34. Kieran, M., V. Blank, F. Logeat, J. Vandekerekhove, F. Lottspeich, O. Le Bail, M. B. Urban, P. Kourilsky, P. A. Baeuerle, and A. Israel. 1990. The DNA binding subunit of NF-κ B is identical to factor KBF1 and homologous to the rel oncogene product. . Cell 62:1007.
35. Ziegler Heitbrock, H. W., A. Wedel, W. Schraut, M. Strobel, P. Wendelgass, T. Sternsdorf, P. A. Bauerle, J. G. Haas, and G. Riethmuller. 1994. Tolerance to lipopolysaccharide involves mobilization of nuclear factor kappa B with predominance of p50 homodimers. J. Biol. Chem. 269:17001.
36. Battafarano, R. J., P. S. Dahlberg, C. A. Ratz, J. W. Johnston, B. H. Gray, J. R. Haseman, K. H. Mayo, and D. L. Dunn. 1995. Peptide derivatives of three distinct lipopolysaccharide binding proteins inhibit lipopolysaccharide-induced tumor necrosis factor-α secretion in vitro. Surgery 118:318.
37. Ingalls, R. R., and D. T. Golenbock. 1995. CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide. J. Exp. Med. 181:1473.
38. Brown, M. S., and J. L. Goldstein. 1985. Scavenger cell receptor shared. Nature 316:680.
39. Gazzano Santoro, H., K. Meszaros, C. Birr, S. F. Carroll, G. Theofan, A. H. Horwitz, E. Lim, S. Aberle, H. Kasler, and J. B. Parent. 1994. Competition between rBPI23, a recombinant fragment of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding protein for binding to LPS and Gram-negative bacteria. Infect. Immun. 62:1185.
40. Hambleton, J., S. L. Weinstein, L. Lem, and A. L. DeFranco. 1996. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA 93:2774.
41. Gegner, J. A., R. J. Ulevitch, and P. S. Tobias. 1995. Lipopolysaccharide (LPS) signal transduction and clearance: dual roles for LPS binding protein and membrane CD14. J. Biol. Chem. 270:5320.
42. Delude, R. L., M. J. Fenton, R. Savedra, Jr., P. Y. Perera, S. N. Vogel, R. Thieringer, and D. T. Golenbock. 1994. CD14-mediated translocation of nuclear factor-κ B induced by lipopolysaccharide does not require tyrosine kinase activity. J. Biol. Chem. 269:22253.
43. 2 integrin in vivo. J. Leukocyte Biol. 59:145.
44. Ding, A., S. Hwang, H. M. Lander, and Q. W. Xie. 1995. Macrophages derived from C3H/HeJ (Lpsd) mice respond to bacterial lipopolysaccharide by activating NF-κ B. . J. Leukocyte Biol. 57:174.
45. Takasuka, N., K. Matsuura, S. Yamamoto, and K. S. Akagawa. 1995. Suppression of TNF-α mRNA expression in LPS-primed macrophages occurs at the level of nuclear factor-κB activation, but not at the level of protein kinase C or CD14 expression. J. Immunol. 154:4803.
46. Beutler, B. 1992. Application of transcriptional and posttranslational reporter constructs to the analysis of tumor necrosis factor gene regulation. Am. J. Med. Sci. 303:129.
47. Biragyn, A., and S. A. Nedospasov. 1995. Lipopolysaccharide-induced expression of TNF-α gene in the macrophage cell line ANA-1 is regulated at the level of transcription processivity. J. Immunol. 155:674.
48. Chen, F., D. C. Kuhn, S. C. Sun, L. J. Gaydos, and L. M. Demers. 1995. Dependence and reversal of nitric oxide production on NF-κ B in silica and lipopolysaccharide-induced macrophages.. Biochem. Biophvs. Res. Commun. 214:839.
49. Eigler, A., J. Moeller, and S. Endres. 1995. Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macrophage cell line RAW 264.7. J. Immunol. 154:4048.
50. Salkowski, C. A., G. Detory, R. McNally, N. van Rooijen, and S. N. Vogel. 1997. Regulation of inducible nitric oxide synthase messenger RNA expression and nitric oxide production by lipopolysaccharide in vivo. J. Immunol. 158:905.
51. Chaundri, G. 1997. Differential regulation in biosynthesis of cell surface and secreted TNF-α in LPS-stimulated murine macrophages. J. Leukocyte Biol. 62: 249.
52. Sivo, J., and S. N. Vogel. 1996. IL-10 differentially regulates mRNA expression induced by lipopolysaccharide and interferons in murine peritoneal macrophages. J. Endotoxin Res. 3:407.
53. Norgard, M. V., L. L. Arndt, D. R. Akins, L. L. Curetty, D. A. Harrich, and J. D. Radolf. 1996. Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-κ B. Infect. Immun. 64:3845.
54. Vogel, S. N., C. L. Manthey, P. Y. Perera, Z. Y. Li, and B. E. Henricson. 1995. Dissection of LPS-induced signaling pathways in murine macrophages using LPS analogs, LPS mimetics, and agents unrelated to LPS. Prog. Clin. Biol. Res. 392: 421.
55. Cleveland, M. G., J. D. Gorham, T. L. Murphy, E. Tuomanen, and K. M. Murphy. 1996. Lipoteichoic acid preparations of Gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway. Infect. Immun. 64:1906.