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See, for example, Hull, D.L. in The Darwinian Heritage (ed. Kohn, D.) 773-812 (Princeton University Press, Princeton, 1985).
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Malthus had made the dire prediction that population would increase faster than the food supply, leading to fierce competition among the members of a species
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Malthus had made the dire prediction that population would increase faster than the food supply, leading to fierce competition among the members of a species.
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Mechnikoff, Darwinism, and the phagocytic theory
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(Oxford University Press, Oxford
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Metchnikoff's early elaboration was in the context of the phagocyte's contribution to a protective inflammation in Lectures on the Comparative Pathology of Inflammation (Dover reprint, New York, 1968), first published in French in 1892, but he later extended it more broadly as the leading player in defense against all infectious diseases in Immunity in the Infectious Diseases (Johnson reprint, New York, 1968), first published in French in
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Metchnikoff's early elaboration was in the context of the phagocyte's contribution to a protective inflammation in Lectures on the Comparative Pathology of Inflammation (Dover reprint, New York, 1968), first published in French in 1892, but he later extended it more broadly as the leading player in defense against all infectious diseases in Immunity in the Infectious Diseases (Johnson reprint, New York, 1968), first published in French in 1901.
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(1901)
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19
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Pasteur wrote a letter to C. James, author of a scurrilous attack on Darwin's evolution entitled Du Dorwinisme ou I'Homme Singe. "I read enough to be charmed by your very elegant and clear style, and by the high purpose and healthy doctrines that have inspired this excellent book", cited in Conry, Y. (Vrin, Paris, 1974)
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In 1877, Pasteur wrote a letter to C. James, author of a scurrilous attack on Darwin's evolution entitled Du Dorwinisme ou I'Homme Singe. "I read enough to be charmed by your very elegant and clear style, and by the high purpose and healthy doctrines that have inspired this excellent book", cited in Conry, Y. L'Introduction du Darvinisme en France au XIX Siècle p. 231 (Vrin, Paris, 1974).
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English translation in Collected Papers of Paul Ehrlich, vol. 2, 31-44 (Pergamon, London, 1957)
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Ehrlich, P. Z. Hyg. Infektkr. 12, 183-203, (1892). English translation in Collected Papers of Paul Ehrlich, vol. 2, 31-44 (Pergamon, London, 1957).
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Some still believed in the inheritance of acquired characteristics, including S. Arloing, who said in his book Les Virus (Alcan, Paris,),"... when [the father] participates in the act of insemination, he may transmit a part of the immunity which he enjoys. The male ovule ... has been dynamically modified ... it carries a vaccinating substance which spreads in all of the cells of the embryo and fetus."
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Some still believed in the inheritance of acquired characteristics, including S. Arloing, who said in his book Les Virus p. 285 (Alcan, Paris, 1891),"... when [the father] participates in the act of insemination, he may transmit a part of the immunity which he enjoys. The male ovule ... has been dynamically modified ... it carries a vaccinating substance which spreads in all of the cells of the embryo and fetus."
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English translation in Collected Papers of Paul Ehrlich, vol. 2, 107-125. These concepts were more fully elaborated several years later in Ehrlich's Croonian Lecture before the Royal Society Proc. R. Soc. Lond. B 66, 42-448 (1900) and in Collected Papers, vol. 2 178-195
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Ehrlich, P. Klin. Jahrb. 60, 299-333 (1897). English translation in Collected Papers of Paul Ehrlich, vol. 2, 107-125. These concepts were more fully elaborated several years later in Ehrlich's Croonian Lecture before the Royal Society Proc. R. Soc. Lond. B 66, 42-448 (1900) and in Collected Papers, vol. 2, 178-195.
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The theory has sometimes been attacked because Burnet was wrong about some of its ancillary propositions, most notably about the mechanism and significance of immunological tolerance
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