Randomized, placebo-controlled, double blind, crossover design trial of the efficacy and safety of zestra for women in women with and without female sexual arousal disorder

Journal of Sex and Marital Therapy

Volumn 29, Issue , 2003, Pages 33-44

  Ferguson, David M ^a   Steidle, Christopher P ^b   Singh, Gita S ^b   Alexander, J Steven ^b   Weihmiller, Mary K ^b   Crosby, Martin G ^c  

^a Clinical Development Services   (United States)

^b Northeast Indiana Urology   (United States)

^c QualiLife Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; SEROTONIN UPTAKE INHIBITOR; VEGETABLE OIL;

ADULT; ARTICLE; BURNING SENSATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONSUMER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FEMALE GENITAL SYSTEM; FEMALE SEXUAL DYSFUNCTION; HUMAN; INTERVIEW; MASSAGE; MEDICAL SPECIALIST; ORGASM; PHYSICAL EXAMINATION; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SATISFACTION; SENSATION; SEXUAL AROUSAL; SEXUAL BEHAVIOR; STATISTICAL SIGNIFICANCE;

ADMINISTRATION, TOPICAL; ADULT; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; PLANT OILS; QUESTIONNAIRES; SEXUAL DYSFUNCTIONS, PSYCHOLOGICAL; VULVA;

EID: 0037229929     PISSN: 0092623X     EISSN: 15210715     Source Type: Journal    
DOI: 10.1080/713847125     Document Type: Article

References (14)

1. Andersson, K. E., & Stief, C. G. (1997). Neurotransmission and the contraction and relaxation of penile erectile tissues. World Journal of Urology, 15(1), 14-20.
2. Basson, R., Berman, I., Burnett, A., Derogatis, L., Ferguson, D., Fourcroy, I., Goldstein, I., Graziottin, A., Heiman, J., Laan, B., Leiblum, S., Padma-Nathan, H., Rosen, R., Segraves, K., Segraves, R. T., Shabsigh, R., Sipski, M., Wagner, G., & Whipple, B. (2000). Report of the International Consensus Development Conference on female sexual dysfunction: Definitions and classifications. Journal of Urology, 163, 888-893.
3. Caruso, S., Intelisano, O., Lupo, L., & Agnello, C. (2001). Premenopausal women affected by sexual arousal disorder treated with sildenafil: A double-blind, crossover, placebo-controlled study. British Journal of Obstetrics and Gynecology, 108, 623-628.
4. Derogatis, L. (May, 2000). Female Sexual Distress Scale: A preliminary report. Paper presented at the American Urological Association Annual Meeting, American Foundation for Urologic Disease.
5. Dines, K. C., Cotter, M. A., & Cameron, N. F. (1996). Effectiveness of natural oils as sources of gamma-linolinic acid to correct peripheral nerve conduction velocity abnormalities in diabetic rats: Modulation by thromboxane A2 inhibition. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 55(3), 159-75.
6. Ferguson, D. M. (2002). Clinical trial development in female sexual dysfunction. Journal of Sex & Marital Therapy, 28 (Suppl.), 77-83.
7. Islam, A., Rosen, R., Phillips, N., Ferguson, D., Mitchel, J., Ayers, C., & Yeager, J. (2001). Topical alprostadil in the treatment of female sexual arousal disorder: A pilot study. Journal of Sex & Marital Therapy, 27, 531-540.
8. Ito, T. Y., Trant, A. S., & Polan, M. L. (2001). A double-blind placebo-controlled study of ArginMax, a nutritional supplement for enhancement of female sexual function. Journal of Sex & Marital Therapy, 27, 541-549.
9. Rosen, R. C., Phillips, N. A., Gendrano, N. C., & Ferguson, D. M. (1999). Oral phen-tolamine and female sexual arousal disorder: A pilot study. Journal of Sex & Marital Therapy, 25, 137-144.
10. Rosen, R., Brown, C., Heiman, J., Leiblum, S., Meston, C., Shabsigh, R., Ferguson, D., & DAgostino, R. (2000). The Female Sexual Function Index (FSFI): A multidimensional self-report instrument for the assessment of female sexual function. Journal of Sex & Marital Therapy, 26, 191-208.
11. Sipski, M. L., Rosen, R. C., Alexander, C. J., & Hamer, R. M. (2000). Sildenafil effects on sexual and cardiovascular responses in women with spinal cord injury. Urology, 55, 812-815.
12. Teng, C. M., Lin, C. H., Ko, F. N., Wu, T. S., & Huang, T. F. (1994). The relaxant action of osthole isolated from Angelica pubescens in guinea-pig trachea. Naunyn Schmiedeberg’s Archive Pharmacologie, 349(2), 202-208.
13. U.S. Food and Drug Administration (2000). Guidance for industry, female sexual dysfunction: Clinical development of drugproducts for treatment. Rockville, MD: U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER).
14. VIVUS (2001). Press release: VIVUS announces positive results in Phase II trial evaluating ALISTA™for the treatment of female sexual arousal disorders. Mountain View, CA: VIVUS.