N-ras mutation in a canine lymphoma: Short communication

Acta Veterinaria Hungarica

Volumn 51, Issue 1, 2003, Pages 91-94

  Mayr, B ^a   Holzheu, M ^a   Schaffner, G ^b   Reifinger, M ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Dog; Lymphoma; Mutation; N ras

Indexed keywords

ASPARTIC ACID; GLYCINE;

ARTICLE; CODON; DOG DISEASE; GENETIC MODEL; LYMPHOMA; MOLECULAR GENETICS; MUTATION; NONHUMAN; ONCOGENE N RAS; PROMOTER REGION; SCREENING;

ANIMALS; DNA PRIMERS; DOG DISEASES; DOGS; FEMALE; GENES, RAS; LYMPHOMA; MALE; POINT MUTATION; POLYMERASE CHAIN REACTION;

CANIS FAMILIARIS;

EID: 0037229914     PISSN: 02366290     EISSN: None     Source Type: Journal    
DOI: 10.1556/AVet.51.2003.1.8     Document Type: Article

References (17)

1. Ahuja, H. G., Foti, A., Bar Eli, M. and Cline, M. J. (1990): The pattern of mutational involvement of Ras genes in human hematologic malignancies determined by DNA amplification and direct sequencing. Blood 75, 1684-1690.
2. Barbacid, M. (1990): Ras oncogenes: their role in neoplasia. Eur. J. Clin. Invest. 20, 225-235.
3. Bos, J. L. (1989): Ras oncogenes in human cancer: A review. Cancer Res. 49, 4682-4689.
4. Browett, P. J. and Norton, J. D. (1989): Analysis of ras gene mutations and methylation state in human leukemias. Oncogene 4, 1029-1036.
5. Edwards, M. D., Pazzi, K. A., Gumerlock, P. H. and Madewell, B. R. (1993): c-N-ras is activated infrequently in canine malignant lymphoma. Toxicol. Pathol. 21, 288-291.
6. Mayr, B. and Reifinger, M. (2002): Canine tumour suppressor gene p53 mutation in a case of anaplastic carcinoma of the intestine. Acta Vet. Hung. 50, 31-35.
7. Mayr, B., Winkler, G., Schaffner, G., Reifinger, M. and Brem, G. (2002a): N-ras mutation in a feline lymphoma. Low frequency of N-ras mutations in a series of feline, canine and bovine lymphomas. Vet. J. 163, 326-328.
8. Mayr, B., Zwetkoff, S., Schaffner, G. and Reifinger, M. (2002b): Tumour suppressor gene p53 mutation in a case of haemangiosarcoma of a dog. Acta Vet. Hung. 50, 157-160.
9. Müllenbach, J. P., Pagoda, L. and Welter, C. (1989): An efficient salt-chloroform extraction of DNA from blood and tissues. Trends Genet. 5, 391.
10. Nakao, M., Janssen, J. W., Seriu, T. and Bartram, C. R. (2000): Rapid and reliable detection of N-ras mutations in acute lymphoblastic leukemia by melting curve analysis using LightCycler technology. Leukemia 14, 312-315.
11. Neri, A., Knowles, D. M., Greco, A., McCormick, F. and Dalla-Favera, R. (1988): Analysis of ras oncogene mutations in human lymphoid malignancies. Proc. Nat. Acad. Sci. USA 85, 9268-9272.
12. Rodenhuis, S. (1992): Ras and human tumors. Semin. Cancer Biol. 3, 241-247.
13. Saunders, K. A., Madewell, B. R., Oreffo, V. I., Kraegel, S. A. and Gumerlock, P. H. (1992): Nucleotide sequence of canine c-N-ras: codons 1 to 71. Am. J. Vet. Res. 53, 600-603.
14. Soussi, T. (2001): Ha-ras, N-ras et Ki-ras. Bull. Cancer 88, 131-133.
15. Teich, N. M. (1997): Oncogenes and cancer oncogenes and cancer. In: Franks, L. M. and Teich, N. M. (eds) Introduction to the Cellular and Molecular Biology of Cancer. Oxford University Press, Oxford, New York, Tokyo, 3rd edition, p. 181.
16. Watzinger, F., Mayr, B., Gamerith, R., Vetter, C. and Lion, T. (2001): Comparative analysis of ras proto-oncogene mutations in selected mammalian tumours. Mol. Carcinogen. 30, 190-198.
17. Watzinger, F., Mayr, B., Haring, E. and Lion, T. (1998): High sequence similarity within ras exon 1 and 2 in different mammalian species and phylogenetic divergence of the ras gene family. Mamm. Genome 9, 214-219.