Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk

American Journal of Human Genetics

Volumn 72, Issue 1, 2003, Pages 208-212

  Xu, Jianfeng ^a   Lilly Zheng, S ^a   Komiya, Akira ^b   Mychaleckyj, Josyf C ^a   Isaacs, Sarah D ^b   Chang, Baoli ^a   Turner, Aubrey R ^a   Ewing, Charles M ^b   Wiley, Kathleen E ^b   Hawkins, Gregory A ^a   Bleecker, Eugene R ^a   Walsh, Patrick C ^b   Meyers, Deborah A ^a   Isaacs, William B ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTATE SPECIFIC ANTIGEN; SCAVENGER RECEPTOR; SCAVENGER RECEPTOR 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER RISK; CANCER SCREENING; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MEDICAL EXAMINATION; PRIORITY JOURNAL; PROSTATE CANCER;

EID: 0037219568     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/345802     Document Type: Article

References (14)

1. Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, et al (2002) Germline mutations in the ribonuclease L gene in families showing linkage with HPC1. Nat Genet 30:181-184
2. De Matzo AM, Marchi VL, Epstein JI, Nelson WG (1999) Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis. Am J Pathol 155:1985-1992
3. Emi M, Asaoka H, Matsumoto A, Itakura H, Kurihara Y, Wada Y, Kanamori H, Yazaki Y, Takahashi E, Lepert M, Lalouel JM, Kodama T, Mukai T (1993) Structure, organization, and chromosomal mapping of the human macrophage scavenger receptor gene. J Biol Chem 268:2120-2125
4. Excoffier L, Slatkin M (1995) Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 12:921-927
5. Kodama T, Freeman M, Rohrer L, Zabrecky J, Matsudaira P, Krieger M (1990) Type I macrophage scavenger receptor contains alpha-helical and collagen-like coiled coils. Nature 343:531-535
6. Lissbrant IF, Stattin P, Wikstrom P, Damber JE, Egevad L, Bergh A (2000) Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival. Int J Oncol 17:445-451
7. Nelson WG, De Marzo AM, DeWeese TL (2001) The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention. Urology Suppl 57:39-45
8. Platt N, Gordon S (2001) Is the class A macrophage scavenger receptor (SR-A) multifunctional? The mouse's tale. J Clin Invest 108:649-654
9. Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA (2002) Score tests for association between traits and haplotypes when linkage phase is ambigious. Am J Hum Genet 70:425-434
10. Shimura S, Yang G, Ebara S, Wheeler TM, Frolov A, Thompson TC (2000) Reduced infiltration of tumor-associated macrophages in human prostate cancer: Association with cancer progression. Cancer Res 60:5857-5861
11. Tavtigian SV, Simard J, Teng DH, Abtin V, Baumgard M, Beck A, Camp NJ, et al (2001) A candidate prostate cancer susceptibility gene at chromosome 17p. Nat Genet 27:172-180
12. Wang L, McDonnell SK, Elkins DA, Slager SL, Christensen E, Marks AF, Cunningham JM. Peterson BJ, Jacobsen SJ, Cerhan JR, Blute ML, Schaid DJ, Thibodeau SN (2002) Analysis of the RNASEL gene in familial and sporadic prostate cancer. Am J Hum Genet 71:116-123
13. Weir BS (1996) Genetic Data Analysis II: Methods for Discrete Population Genetic Data. Sinauer Association, Sunderland, MA
14. Xu J, Zheng SL, Komiya A, Mychaleckyj JC, Isaacs SD, Hu JJ, Sterling D, et al (2002) Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet 32:321-325