Acute profound thrombocytopenia after use of eptifibatide for coronary stenting

Catheterization and Cardiovascular Interventions

Volumn 58, Issue 1, 2003, Pages 73-75

  Salengro, Emmanuel ^a   Mulvihill, Niall T ^a   Farah, Bruno ^a  

^a CLINIQUE PASTEUR   (France)

Author keywords

Angioplasty; Eptifibatide; Stenting; Thrombocytopenia

Indexed keywords

ACETYLSALICYLIC ACID; EPTIFIBATIDE;

AGED; ANGINA PECTORIS; ANGIOPLASTY; ANTICOAGULANT THERAPY; ARTICLE; BLOOD CELL COUNT; CASE REPORT; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY OBSTRUCTION; CORONARY STENT; FOREARM; HEART CATHETERIZATION; HUMAN; HYPERTENSION; INTENSIVE CARE UNIT; KIDNEY FUNCTION; LABORATORY TEST; MALE; RIGHT CORONARY ARTERY; SURGICAL TECHNIQUE; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA;

AGED; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BLOOD VESSEL PROSTHESIS IMPLANTATION; CORONARY STENOSIS; HUMANS; MALE; PEPTIDES; PLATELET AGGREGATION INHIBITORS; STENTS; THROMBOCYTOPENIA;

EID: 0037219188     PISSN: 15221946     EISSN: None     Source Type: Journal    
DOI: 10.1002/ccd.10390     Document Type: Article

References (10)

1. EPILOG investigators. Platelet glycoproteins IIb/IIIa blockade with abciximab and low dose heparin during percutaneous coronary revascularization. N Engl J Med 1997;336:1689-1696.
2. IMPACT-II investigators. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Lancet 1997;349:1422-1428.
3. PURSUIT investigators. Inhibition of platelet glycoproteins IIb/IIIa with eptifibatide in patients with acute coronary syndromes. N Engl J Med 1998;339:436-443.
4. ESPRIT investigators. Novel dosing regimen of eptifibatide in planned coronary stent implantation (ESPRIT): A randomised, placebo-controled trial. Lancet 2000;356:2037-2044.
5. Montalescot G, Barragan P, Wittenberg O, et al. Platelet glycoprotein IIb/IIIa Inhibition with coronary stenting for acute myocardial infarction (ADMIRAL). N Engl J Med 2001;344:1895-1903.
6. Berkowitz SD, Sane DC, Sigmon ICN, et al. Occurence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularisation. J Am Coll Cardiol 1998;32:311-319.
7. Giugliano RP. Drug-induced thrombocytopenia: Is it a serious concern for glycoproteins IIb/IIIa receptor inhibitors? J Thrombosis Thrombolysis 1998;5:191-202.
8. Hongo RH, Brent BN. Association of eptifibatide and acute profound thrombocytopenia. Am J Cardiol 2001;88:428-431.
9. Aster RH. Heparin-induced thrombocytopenia. N Engl J Med 1995;332:1374-1376.
10. Kereiakes DJ, Essel JH, Abbottsmith CW, et al. Abciximab-asssociated profound thrombocytopenia: Therapy with immunoglobulin and platelet transfusion. Am J Cardiol 1996;78:1161-1163.