메뉴 건너뛰기




Volumn 3, Issue 1, 2003, Pages 11-15

Catechol-O-methyl transferase (COMT) inhibitors in patients with Parkinson's disease: Is COMT genotype a useful indicator of clinical efficacy?

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; CATECHOL METHYLTRANSFERASE INHIBITOR; ENTACAPONE; TOLCAPONE;

EID: 0037219072     PISSN: 11752203     EISSN: None     Source Type: Journal    
DOI: 10.2165/00129785-200303010-00003     Document Type: Review
Times cited : (4)

References (43)
  • 1
    • 0029883235 scopus 로고    scopus 로고
    • The response to levodopa in Parkinson's disease: Imposing pharmacological law and order
    • Nutt J, Holford NHG. The response to levodopa in Parkinson's disease: imposing pharmacological law and order. Ann Neurol 1996; 39: 561-73
    • (1996) Ann Neurol , vol.39 , pp. 561-573
    • Nutt, J.1    Holford, N.H.G.2
  • 2
    • 0035353725 scopus 로고    scopus 로고
    • Frequency of levodopa-related dyskinesia and motor fluctuation as estimated from the cumulative literature
    • Ahlskog JE, Muenter MD. Frequency of levodopa-related dyskinesia and motor fluctuation as estimated from the cumulative literature. Mov Disord 2001; 16: 448-58
    • (2001) Mov Disord , vol.16 , pp. 448-458
    • Ahlskog, J.E.1    Muenter, M.D.2
  • 3
    • 0034109726 scopus 로고    scopus 로고
    • The spectrum of levodopa induced dyskinesias
    • Fahn S. The spectrum of levodopa induced dyskinesias. Ann Neurol 2000; 47 Suppl. 1: S2-S11
    • (2000) Ann Neurol , vol.47 , Issue.SUPPL. 1
    • Fahn, S.1
  • 4
    • 0016829492 scopus 로고
    • Catechol-O-methyl transferase: Pharmacological aspects and physiological role
    • Guldberg HC, Marsden CA. Catechol-O-methyl transferase: pharmacological aspects and physiological role. Pharmacol Rev 1975; 27: 135-206
    • (1975) Pharmacol Rev , vol.27 , pp. 135-206
    • Guldberg, H.C.1    Marsden, C.A.2
  • 5
    • 0034642349 scopus 로고    scopus 로고
    • Issues important for rational COMT inhibition
    • Dingemanse J. Issues important for rational COMT inhibition. Neurology 2000; 55 Suppl. 4: S24-7
    • (2000) Neurology , vol.55 , Issue.SUPPL. 4
    • Dingemanse, J.1
  • 6
    • 0025187695 scopus 로고
    • Molecular cloning and characterization of rat liver catechol-O-methyltransferase
    • Salminen M, Lundström K, Tilgmann C, et al. Molecular cloning and characterization of rat liver catechol-O-methyltransferase, Gene 1990; 93: 241-5
    • (1990) Gene , vol.93 , pp. 241-245
    • Salminen, M.1    Lundström, K.2    Tilgmann, C.3
  • 7
    • 0026034792 scopus 로고
    • Human catechol-O-methyltransferase: Cloning and expression of the membrane-associated form
    • Bertocci B, Miggiano V, Da Prada M, et al. Human catechol-O-methyltransferase: cloning and expression of the membrane-associated form. Proc Natl Acad Sci U S A 1991; 88: 1416-20
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 1416-1420
    • Bertocci, B.1    Miggiano, V.2    Da Prada, M.3
  • 8
    • 0025801604 scopus 로고
    • Cloning and characterization of human placental catechol-O-methyltransferase cDNA
    • Lundström K, Salminen M, Jalanko A, et al. Cloning and characterization of human placental catechol-O-methyltransferase cDNA. DNA Cell Biol 1991; 10: 181-9
    • (1991) DNA Cell Biol , vol.10 , pp. 181-189
    • Lundström, K.1    Salminen, M.2    Jalanko, A.3
  • 9
    • 0022877399 scopus 로고
    • Assignment of the catechol-O-methyltransferase gene to human chromosome 22 in somatic cell hybrids
    • Brahe C, Bannetta P, Meera Khan P, et al. Assignment of the catechol-O-methyltransferase gene to human chromosome 22 in somatic cell hybrids. Hum Genet 1986; 74 (3): 230-4
    • (1986) Hum Genet , vol.74 , Issue.3 , pp. 230-234
    • Brahe, C.1    Bannetta, P.2    Meera Khan, P.3
  • 10
    • 0026518652 scopus 로고
    • Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2
    • Grossman MH, Emanuel BS, Budarf ML. Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2. Genomics 1992; 12 (4): 822-5
    • (1992) Genomics , vol.12 , Issue.4 , pp. 822-825
    • Grossman, M.H.1    Emanuel, B.S.2    Budarf, M.L.3
  • 11
    • 0026553253 scopus 로고
    • The human catechol-O-methyltransferase (COMT) gene maps to band q11.2 of chromosome 22 and shows a frequent RFLP with BgII
    • Winqvist R, Lundström K, Salminen M, et al. The human catechol-O-methyltransferase (COMT) gene maps to band q11.2 of chromosome 22 and shows a frequent RFLP with BgII. Cytogenet Cell Genet 1992; 59: 253-7
    • (1992) Cytogenet Cell Genet , vol.59 , pp. 253-257
    • Winqvist, R.1    Lundström, K.2    Salminen, M.3
  • 12
    • 0031037713 scopus 로고    scopus 로고
    • Expression and intracellular localization of catechol O-methyltransferase (COMT) in transfected mammalian cells
    • Ulmanen I, Peránen J, Tenhunen J, et al. Expression and intracellular localization of catechol O-methyltransferase (COMT) in transfected mammalian cells. Eur J Biochem 1997; 243: 452-9
    • (1997) Eur J Biochem , vol.243 , pp. 452-459
    • Ulmanen, I.1    Peránen, J.2    Tenhunen, J.3
  • 13
    • 0033888324 scopus 로고    scopus 로고
    • Nuclear localization of catechol-O-methyltransferase in neoplastic and nonneoplastic mammary epithelial cells
    • Weisz J, Fritz-Wolz G, Gestl S, et al. Nuclear localization of catechol-O-methyltransferase in neoplastic and nonneoplastic mammary epithelial cells. Am J Pathol 2000; 156: 1841-8
    • (2000) Am J Pathol , vol.156 , pp. 1841-1848
    • Weisz, J.1    Fritz-Wolz, G.2    Gestl, S.3
  • 14
    • 0028291661 scopus 로고
    • Distribution of catechol-O-methyltransferase in rat tissues
    • Karhunen T, Tilgmann C, Ulmanen I, et al. Distribution of catechol-O-methyltransferase in rat tissues. J Histochem Cytochem 1994; 42: 1079-90
    • (1994) J Histochem Cytochem , vol.42 , pp. 1079-1090
    • Karhunen, T.1    Tilgmann, C.2    Ulmanen, I.3
  • 15
    • 0027964721 scopus 로고
    • Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters
    • Tenhunen J, Salminen M, Lundström K, et al. Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters. Eur J Biochem 1994; 223: 1049-59
    • (1994) Eur J Biochem , vol.223 , pp. 1049-1059
    • Tenhunen, J.1    Salminen, M.2    Lundström, K.3
  • 16
    • 0029117652 scopus 로고
    • Cloning, expression and structure of catechol-O-methyltransferase
    • Lundström K, Tenhunen J, Tilgmann C, et al. Cloning, expression and structure of catechol-O-methyltransferase. Biochem Biophys Acta 1995; 125: 1-10
    • (1995) Biochem Biophys Acta , vol.125 , pp. 1-10
    • Lundström, K.1    Tenhunen, J.2    Tilgmann, C.3
  • 17
    • 0031878242 scopus 로고    scopus 로고
    • Induction of nuclear catechol-O-methyltransferase by estrogens in hamster kidney: Implications for estrogen-induced renal cancer
    • Weisz J, Fritz-Wolz G, Clawson GA, et al. Induction of nuclear catechol-O-methyltransferase by estrogens in hamster kidney: implications for estrogen-induced renal cancer. Carcinogenesis 1998; 19: 1307-12
    • (1998) Carcinogenesis , vol.19 , pp. 1307-1312
    • Weisz, J.1    Fritz-Wolz, G.2    Clawson, G.A.3
  • 18
    • 0018228644 scopus 로고
    • Human biochemical genetics of plasma dopamine-beta-hydroxylase and erythrocyte catechol-O-methyltransferase
    • Weinshilboum RM. Human biochemical genetics of plasma dopamine-beta-hydroxylase and erythrocyte catechol-O-methyltransferase. Hum Genet 1978; Suppl. 1: 101-12
    • (1978) Hum Genet , Issue.SUPPL. 1 , pp. 101-112
    • Weinshilboum, R.M.1
  • 19
    • 0018378334 scopus 로고
    • Catechol-O-methyltransferase: Thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity
    • Scanlon PD, Raymond FA, Weinshilboum RM. Catechol-O-methyltransferase: thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity. Science 1979; 203: 63-5
    • (1979) Science , vol.203 , pp. 63-65
    • Scanlon, P.D.1    Raymond, F.A.2    Weinshilboum, R.M.3
  • 20
    • 0025119634 scopus 로고
    • Human liver catechol-O-methyltransferase pharmacogenetics
    • Boudïková B, Szumlanski C, Maidak B, et al. Human liver catechol-O-methyltransferase pharmacogenetics. Clin Pharmacol Ther 1990; 48: 381-9
    • (1990) Clin Pharmacol Ther , vol.48 , pp. 381-389
    • Boudïková, B.1    Szumlanski, C.2    Maidak, B.3
  • 21
    • 0030004521 scopus 로고    scopus 로고
    • Human catechol-O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders
    • Lachman HM, Papolos DF, Saito T, et al. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 1996; 6: 243-50
    • (1996) Pharmacogenetics , vol.6 , pp. 243-250
    • Lachman, H.M.1    Papolos, D.F.2    Saito, T.3
  • 22
    • 0030904954 scopus 로고    scopus 로고
    • Genetic polymorphism of catechol-O-methyltransferase (COMT): Correlation of genotype with individual variation of S-COMT activity and comparison of the allele frequencies in the normal population and parkinsonian patients in Finland
    • Syvänen AC, Tilgmann C, Rinne JO, et al. Genetic polymorphism of catechol-O-methyltransferase (COMT): correlation of genotype with individual variation of S-COMT activity and comparison of the allele frequencies in the normal population and parkinsonian patients in Finland. Pharmacogenetics 1997; 7: 65-71
    • (1997) Pharmacogenetics , vol.7 , pp. 65-71
    • Syvänen, A.C.1    Tilgmann, C.2    Rinne, J.O.3
  • 23
    • 0028918413 scopus 로고
    • Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme
    • Lotta T, Vidgren J, Tilgmann C, et al. Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 1995; 34: 4202-10
    • (1995) Biochemistry , vol.34 , pp. 4202-4210
    • Lotta, T.1    Vidgren, J.2    Tilgmann, C.3
  • 24
    • 0028210328 scopus 로고
    • Crystal structure of catechol O-methyltransferase
    • Vidgren J, Svensson LA, Liljas A. Crystal structure of catechol O-methyltransferase. Nature 1994; 368: 354-8
    • (1994) Nature , vol.368 , pp. 354-358
    • Vidgren, J.1    Svensson, L.A.2    Liljas, A.3
  • 25
    • 0034942038 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder and a novel polymorphism adjacent to the oestrogen response element (ERE 6) upstream from the COMT gene
    • Kinnear C, Niehaus DJ, Seedat S, et al. Obsessive-compulsive disorder and a novel polymorphism adjacent to the oestrogen response element (ERE 6) upstream from the COMT gene. Psychiatr Genet 2001; 11; 85-7
    • (2001) Psychiatr Genet , vol.11 , pp. 85-87
    • Kinnear, C.1    Niehaus, D.J.2    Seedat, S.3
  • 26
    • 0021201021 scopus 로고
    • Difference in erythrocyte catechol-O-methyltransferase activity between Orientals and Caucasians: Difference in levodopa tolerance
    • Rivera-Calimlim L, Reilly DK. Difference in erythrocyte catechol-O-methyltransferase activity between Orientals and Caucasians: difference in levodopa tolerance. Clin Pharmacol Ther 1984; 35: 804-9
    • (1984) Clin Pharmacol Ther , vol.35 , pp. 804-809
    • Rivera-Calimlim, L.1    Reilly, D.K.2
  • 27
    • 0028294519 scopus 로고
    • Low catechol-O-methyltransferase activity in a Saami population
    • Klemetsdal B, Straume B, Giverhaug T, et al. Low catechol-O-methyltransferase activity in a Saami population. Eur J Clin Pharmacol 1994; 46: 231-5
    • (1994) Eur J Clin Pharmacol , vol.46 , pp. 231-235
    • Klemetsdal, B.1    Straume, B.2    Giverhaug, T.3
  • 28
    • 0028264457 scopus 로고
    • Ethnic differences in erythrocyte catechol-O-methyltransferase activity in black and white Americans
    • McLeod HL, Fang L, Luo X, et al. Ethnic differences in erythrocyte catechol-O-methyltransferase activity in black and white Americans. J Pharmacol Exp Ther 1994; 270: 26-9
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 26-29
    • McLeod, H.L.1    Fang, L.2    Luo, X.3
  • 29
    • 0030895285 scopus 로고    scopus 로고
    • Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder
    • Karayiorgou M, Altemus M, Galke BL, et al. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci U S A 1997; 94: 4572-5
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4572-4575
    • Karayiorgou, M.1    Altemus, M.2    Galke, B.L.3
  • 30
    • 0032777995 scopus 로고    scopus 로고
    • Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
    • Palmatier MA, Kang AM, Kidd KK. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biol Psychiatry 1999; 46: 557-67
    • (1999) Biol Psychiatry , vol.46 , pp. 557-567
    • Palmatier, M.A.1    Kang, A.M.2    Kidd, K.K.3
  • 31
    • 0034323569 scopus 로고    scopus 로고
    • Pharmacogenetics of catechol-O-methyltransferase: Frequency of low activity allele in a Ghanaian population
    • Ameyaw MM, Syvanen AC, Ulmanen I, et al. Pharmacogenetics of catechol-O-methyltransferase: frequency of low activity allele in a Ghanaian population. Hum Mutat 2000; 16: 445-6
    • (2000) Hum Mutat , vol.16 , pp. 445-446
    • Ameyaw, M.M.1    Syvanen, A.C.2    Ulmanen, I.3
  • 32
    • 0034808705 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase (COMT) genetic polymorphism in a Turkish population
    • Kocabas NA, Karakaya AE, Cholerton S, et al. Catechol-O-methyltransferase (COMT) genetic polymorphism in a Turkish population. Arch Toxicol 2001; 75: 407-9
    • (2001) Arch Toxicol , vol.75 , pp. 407-409
    • Kocabas, N.A.1    Karakaya, A.E.2    Cholerton, S.3
  • 33
    • 0017798885 scopus 로고
    • Human erythrocyte catechol-o-methyl transferase: Correlation with lung and kidney activity
    • Weinshilboum RM. Human erythrocyte catechol-o-methyl transferase: correlation with lung and kidney activity. Life Sci 1978; 22: 625-30
    • (1978) Life Sci , vol.22 , pp. 625-630
    • Weinshilboum, R.M.1
  • 34
    • 0028203007 scopus 로고
    • Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone
    • Keränen T, Gordin A, Karlsson M, et al. Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone. Eur J Clin Pharmacol 1994; 46: 151-7
    • (1994) Eur J Clin Pharmacol , vol.46 , pp. 151-157
    • Keränen, T.1    Gordin, A.2    Karlsson, M.3
  • 35
    • 0002456447 scopus 로고    scopus 로고
    • COMT genotype and response to levodopa in Parkinson's disease: Influence of COMT inhibition with entacapone
    • Ruottinen HM, Ulmanen I, Gordin A, et al. COMT genotype and response to levodopa in Parkinson's disease: influence of COMT inhibition with entacapone [abstract]. Mov Disord 1998; 13 Suppl. 2: 120
    • (1998) Mov Disord , vol.13 , Issue.SUPPL. 2 , pp. 120
    • Ruottinen, H.M.1    Ulmanen, I.2    Gordin, A.3
  • 36
    • 0029895288 scopus 로고    scopus 로고
    • A double-blind pharmacokinetic and clinical dose-response study of entacapone as an adjuvant to levodopa therapy in advanced Parkinson's disease
    • Routtinen HM, Rinne UK. A double-blind pharmacokinetic and clinical dose-response study of entacapone as an adjuvant to levodopa therapy in advanced Parkinson's disease. Clin Neuropharmacol 1996; 19: 283-96
    • (1996) Clin Neuropharmacol , vol.19 , pp. 283-296
    • Routtinen, H.M.1    Rinne, U.K.2
  • 37
    • 0015241526 scopus 로고
    • Reduction of catechol-O-methyl-transferase activity by chronic levodopa treatment
    • Weiss JL, Cohn CK, Chase TN. Reduction of catechol-O-methyl-transferase activity by chronic levodopa treatment. Nature 1971; 234: 218-9
    • (1971) Nature , vol.234 , pp. 218-219
    • Weiss, J.L.1    Cohn, C.K.2    Chase, T.N.3
  • 38
    • 0037176816 scopus 로고    scopus 로고
    • COMT genotype and effectiveness of entacapone in patients with fluctuating Parkinson's disease
    • Lee MS, Kim HS, Cho EK, et al. COMT genotype and effectiveness of entacapone in patients with fluctuating Parkinson's disease. Neurology 2002; 58: 564-7
    • (2002) Neurology , vol.58 , pp. 564-567
    • Lee, M.S.1    Kim, H.S.2    Cho, E.K.3
  • 39
    • 0031777394 scopus 로고    scopus 로고
    • Ethnic differences in catechol-O-methyltransferase pharmacogenetics: Frequency of the codon 108/158 low activity allele is lower in Kenyan than Caucasian or south-west Asian individuals
    • McLeod H, Syvänen AC, Githang'a J, et al. Ethnic differences in catechol-O-methyltransferase pharmacogenetics: frequency of the codon 108/158 low activity allele is lower in Kenyan than Caucasian or south-west Asian individuals. Pharmacogenetics 1998; 8: 195-9
    • (1998) Pharmacogenetics , vol.8 , pp. 195-199
    • McLeod, H.1    Syvänen, A.C.2    Githang'a, J.3
  • 40
    • 0020637004 scopus 로고
    • Localization of membrane-bound catechol-O-methyltransferase
    • Rivett AJ, Fracis A, Roth JA. Localization of membrane-bound catechol-O-methyltransferase. J Neurochem 1983; 40: 1494-6
    • (1983) J Neurochem , vol.40 , pp. 1494-1496
    • Rivett, A.J.1    Fracis, A.2    Roth, J.A.3
  • 41
    • 0034084120 scopus 로고    scopus 로고
    • The relationship between COMT genotype and the clinical effectiveness of tolcapone, a COMT inhibitor, in patients with Parkinson's disease
    • Chong DJ, Suchowersky O, Szumlanski C, et al. The relationship between COMT genotype and the clinical effectiveness of tolcapone, a COMT inhibitor, in patients with Parkinson's disease. Clin Neuropharmacol 2000; 23: 143-8
    • (2000) Clin Neuropharmacol , vol.23 , pp. 143-148
    • Chong, D.J.1    Suchowersky, O.2    Szumlanski, C.3
  • 42
    • 0019445434 scopus 로고
    • Gastric emptying rate and the systemic availability of levodopa in the elderly parkinsonian patients
    • Evans MA, Broe GA, Triggs EJ, et al. Gastric emptying rate and the systemic availability of levodopa in the elderly parkinsonian patients. Neurology 1981; 31: 1288-94
    • (1981) Neurology , vol.31 , pp. 1288-1294
    • Evans, M.A.1    Broe, G.A.2    Triggs, E.J.3
  • 43
    • 0030042649 scopus 로고    scopus 로고
    • Entacapone prolongs levodopa response in one month double blind study in parkinsonian patients with levodopa related fluctuations
    • Ruottinen HM, Rinne UK. Entacapone prolongs levodopa response in one month double blind study in parkinsonian patients with levodopa related fluctuations. J Neurol Neurosurg Psychiatry 1996; 60: 36-40
    • (1996) J Neurol Neurosurg Psychiatry , vol.60 , pp. 36-40
    • Ruottinen, H.M.1    Rinne, U.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.