-
1
-
-
0019423065
-
Treatment of Parkinson's disease: Problems with progressing disease
-
Rinne UK. Treatment of Parkinson's disease: problems with progressing disease. J Neural Transm 1981;51:161-74.
-
(1981)
J Neural Transm
, vol.51
, pp. 161-174
-
-
Rinne, U.K.1
-
3
-
-
0016268268
-
Plasma DOPA concentrations and the "on-off" effect after chronic treatment of Parkinson's disease
-
Sweet RD, McDowell FH. Plasma DOPA concentrations and the "on-off" effect after chronic treatment of Parkinson's disease. Neurology 1974;24:953-6.
-
(1974)
Neurology
, vol.24
, pp. 953-956
-
-
Sweet, R.D.1
McDowell, F.H.2
-
4
-
-
0024377955
-
Catechol-O-methyl transferase-inhibiting pyrocatechol derivatives: Synthesis and structure-activity studies
-
Borgulya J, Bruderer H, Bernauer K, Zürcher G, Da Prada M. Catechol-O-methyl transferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies. Helv Chim Acta 1989;72:952-68.
-
(1989)
Helv Chim Acta
, vol.72
, pp. 952-968
-
-
Borgulya, J.1
Bruderer, H.2
Bernauer, K.3
Zürcher, G.4
Da Prada, M.5
-
5
-
-
0024550515
-
Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors
-
Bäckström R, Honkanen E, Pippuri A, et al. Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors. J Med Chem 1989;32:841-6.
-
(1989)
J Med Chem
, vol.32
, pp. 841-846
-
-
Bäckström, R.1
Honkanen, E.2
Pippuri, A.3
-
6
-
-
0026570182
-
Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat
-
Männistö PT, Tuomainen P, Tuominen RK. Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat. Br J Pharmacol 1992;105:569-74.
-
(1992)
Br J Pharmacol
, vol.105
, pp. 569-574
-
-
Männistö, P.T.1
Tuomainen, P.2
Tuominen, R.K.3
-
7
-
-
0026671534
-
Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor Entacapone
-
Nissinen E, Linden I-B, Schultz E, Pohto P. Biochemical and pharmacological properties of a peripherally acting catechol-O-methyltransferase inhibitor Entacapone. Naunyn Schmiedebergs Arch Pharmacol 1992;346:262-6.
-
(1992)
Naunyn Schmiedebergs Arch Pharmacol
, vol.346
, pp. 262-266
-
-
Nissinen, E.1
Linden, I.-B.2
Schultz, E.3
Pohto, P.4
-
8
-
-
0028078890
-
Effect of entacapone, a COMT inhibitor, on clinical disability and levodopa metabolism in parkinsonian patients
-
Kaakkola S, Teräväinen H, Ahtila S, Rita H, Gordin A. Effect of entacapone, a COMT inhibitor, on clinical disability and levodopa metabolism in parkinsonian patients. Neurology 1994;44:77-80.
-
(1994)
Neurology
, vol.44
, pp. 77-80
-
-
Kaakkola, S.1
Teräväinen, H.2
Ahtila, S.3
Rita, H.4
Gordin, A.5
-
9
-
-
0028286186
-
Effect of peripheral catechol-O-methyltransferase inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients
-
Nutt JG, Woodward WR, Beckner RM, et al. Effect of peripheral catechol-O-methyltransferase inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients. Neurology 1994;44:913-9.
-
(1994)
Neurology
, vol.44
, pp. 913-919
-
-
Nutt, J.G.1
Woodward, W.R.2
Beckner, R.M.3
-
10
-
-
0027445460
-
Effect of entacapone, a COMT inhibitor, on the pharmacokinetics of levodopa and on cardiovascular responses in patients with Parkinson's disease
-
Myllylä VV, Sotaniemi KA, Illi A, Suominen K, Keränen T. Effect of entacapone, a COMT inhibitor, on the pharmacokinetics of levodopa and on cardiovascular responses in patients with Parkinson's disease. Eur J Clin Pharmacol 1993;45:419-23.
-
(1993)
Eur J Clin Pharmacol
, vol.45
, pp. 419-423
-
-
Myllylä, V.V.1
Sotaniemi, K.A.2
Illi, A.3
Suominen, K.4
Keränen, T.5
-
11
-
-
0028203007
-
Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone
-
Keränen T, Gordin A, Karlsson M, et al. Inhibition of soluble catechol-O-methyltransferase and single-dose pharmacokinetics after oral and intravenous administration of entacapone. Eur J Clin Pharmacol 1994;46:151-7.
-
(1994)
Eur J Clin Pharmacol
, vol.46
, pp. 151-157
-
-
Keränen, T.1
Gordin, A.2
Karlsson, M.3
-
12
-
-
0028891614
-
Effect of entacapone, a COMT inhibitor, on the pharmacokinetics and metabolism of levodopa after administration of controlled-release levodopacarbidopa in volunteers
-
Ahtila S, Kaakkola S, Gordin A, et al. Effect of entacapone, a COMT inhibitor, on the pharmacokinetics and metabolism of levodopa after administration of controlled-release levodopacarbidopa in volunteers. Clin Neuropharmacol 1995;18:46-57.
-
(1995)
Clin Neuropharmacol
, vol.18
, pp. 46-57
-
-
Ahtila, S.1
Kaakkola, S.2
Gordin, A.3
-
13
-
-
0028137620
-
Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease
-
Merello M, Lees AJ, Webster R, Bovingdon M, Gordin A. Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 1994;57:186-9.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 186-189
-
-
Merello, M.1
Lees, A.J.2
Webster, R.3
Bovingdon, M.4
Gordin, A.5
-
14
-
-
0029881772
-
Effect of one month's treatment with peripherally-acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients
-
Ruottinen H, Rinne UK. Effect of one month's treatment with peripherally-acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients. Clin Neuropharmacol 1996;19:222-33.
-
(1996)
Clin Neuropharmacol
, vol.19
, pp. 222-233
-
-
Ruottinen, H.1
Rinne, U.K.2
-
15
-
-
0028128512
-
18F]-6-L-fluorodopa metabolism: Implications for levodopa therapy of Parkinson's disease
-
18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease. Neurology 1994;44:1292-7.
-
(1994)
Neurology
, vol.44
, pp. 1292-1297
-
-
Sawle, G.V.1
Burn, D.J.2
Morrish, P.K.3
-
16
-
-
0029417246
-
18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease
-
18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease. J Neural Transm [P-D Sect] 1995;10:91-106.
-
(1995)
J Neural Transm [P-D Sect]
, vol.10
, pp. 91-106
-
-
Ruottinen, H.M.1
Rinne, J.O.2
Ruotsalainen, U.H.3
-
17
-
-
0014082977
-
Parkinsonism: Onset, progression, and mortality
-
Hoehn MM, Yahr MD. Parkinsonism: onset, progression, and mortality. Neurology 1967;17:427-42.
-
(1967)
Neurology
, vol.17
, pp. 427-442
-
-
Hoehn, M.M.1
Yahr, M.D.2
-
18
-
-
0000224448
-
Unified Parkinson's Disease Rating Scale
-
members of the UPDRS Development Committee Fahn S, Marsden CD, Calne DB, Goldstein M, eds. Florham Park: Macmillan Healthcare Information
-
Farm S, Elton RL, members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale. In: Fahn S, Marsden CD, Calne DB, Goldstein M, eds. Recent developments in Parkinson's disease, vol II. Florham Park: Macmillan Healthcare Information, 1987:153-63.
-
(1987)
Recent Developments in Parkinson's Disease
, vol.2
, pp. 153-163
-
-
Farm, S.1
Elton, R.L.2
-
19
-
-
0021783191
-
Le test à la L-dopa dans la maladie de Parkinson
-
Esteguy M, Bonnet AM, Kefalos J, Lhermitte F, Agid Y. Le test à la L-dopa dans la maladie de Parkinson. Rev Neurol 1985;141:413-5.
-
(1985)
Rev Neurol
, vol.141
, pp. 413-415
-
-
Esteguy, M.1
Bonnet, A.M.2
Kefalos, J.3
Lhermitte, F.4
Agid, Y.5
-
20
-
-
0024590401
-
Determination of catechol-O-methyltransferase activity in erythrocytes by high performance liquid chromatography with electrochemical detection
-
Schultz E, Nissinen E, Kaakkola S. Determination of catechol-O-methyltransferase activity in erythrocytes by high performance liquid chromatography with electrochemical detection. Biomed Chromatogr 1989;3:64-7.
-
(1989)
Biomed Chromatogr
, vol.3
, pp. 64-67
-
-
Schultz, E.1
Nissinen, E.2
Kaakkola, S.3
-
21
-
-
0026034997
-
Simultaneous determination of levodopa, its main metabolites and carbidopa in plasma by liquid chromatography
-
Wikberg T. Simultaneous determination of levodopa, its main metabolites and carbidopa in plasma by liquid chromatography. J Pharm Biomed Anal 1991;9:167-76.
-
(1991)
J Pharm Biomed Anal
, vol.9
, pp. 167-176
-
-
Wikberg, T.1
-
22
-
-
0026566932
-
Liquid chromatographic determination of a new catechol-O-methyltransferase inhibitor, entacapone, and its Z-isomer in human plasma and urine
-
Karlsson M, Wikberg T. Liquid chromatographic determination of a new catechol-O-methyltransferase inhibitor, entacapone, and its Z-isomer in human plasma and urine. J Pharm Biomed Anal 1992;10:593-600.
-
(1992)
J Pharm Biomed Anal
, vol.10
, pp. 593-600
-
-
Karlsson, M.1
Wikberg, T.2
-
25
-
-
0027514196
-
The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers
-
Keränen T, Gordin A, Harjola V-P, et al. The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers. Clin Neuropharmacol 1993;16:145-56.
-
(1993)
Clin Neuropharmacol
, vol.16
, pp. 145-156
-
-
Keränen, T.1
Gordin, A.2
Harjola, V.-P.3
-
26
-
-
0027436117
-
The effects of the COMT inhibitor entacapone on haemodynamics and peripheral catecholamine metabolism during exercise
-
Sundberg S, Scheinin M, Illi A, Akkila J, Gordin A, Keränen T. The effects of the COMT inhibitor entacapone on haemodynamics and peripheral catecholamine metabolism during exercise. Br J Clin Pharmacol 1993;36:451-6.
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 451-456
-
-
Sundberg, S.1
Scheinin, M.2
Illi, A.3
Akkila, J.4
Gordin, A.5
Keränen, T.6
-
27
-
-
0028046134
-
COMT inhibition by high-dose entacapone does not affect hemodynamics but changes catecholamine metabolism in healthy volunteers at rest and during exercise
-
Illi A, Sundberg S, Koulu M, Scheinin M, Heinävaara S, Gordin A. COMT inhibition by high-dose entacapone does not affect hemodynamics but changes catecholamine metabolism in healthy volunteers at rest and during exercise. Int J Clin Pharmacol Ther 1994;32:582-8.
-
(1994)
Int J Clin Pharmacol Ther
, vol.32
, pp. 582-588
-
-
Illi, A.1
Sundberg, S.2
Koulu, M.3
Scheinin, M.4
Heinävaara, S.5
Gordin, A.6
-
28
-
-
0027770982
-
Catechol-O-methyltransferase inhibitor tolcapone prolongs levodopa/carbidopa action in parkinsonian patients
-
Roberts JW, Cora-Locatelli G, Bravi D, Amantea MA, Mouradian MM, Chase TN. Catechol-O-methyltransferase inhibitor tolcapone prolongs levodopa/carbidopa action in parkinsonian patients. Neurology 1994;44:2685-8.
-
(1994)
Neurology
, vol.44
, pp. 2685-2688
-
-
Roberts, J.W.1
Cora-Locatelli, G.2
Bravi, D.3
Amantea, M.A.4
Mouradian, M.M.5
Chase, T.N.6
-
29
-
-
0027174943
-
Ro 40-7592, a COMT inhibitor, plus levodopa in Parkinson's disease
-
Limousin P, Pollak P, Gervason-Tournier C-L, Hommel M, Perret JE. Ro 40-7592, a COMT inhibitor, plus levodopa in Parkinson's disease. Lancet 1993;341:1605.
-
(1993)
Lancet
, vol.341
, pp. 1605
-
-
Limousin, P.1
Pollak, P.2
Gervason-Tournier, C.-L.3
Hommel, M.4
Perret, J.E.5
-
30
-
-
0029000679
-
Effects of tolcapone in Parkinson's patients taking L-dihydroxyphenylalanine/carbidopa and selegiline
-
Davis TL, Roznoski M, Burns RS. Effects of tolcapone in Parkinson's patients taking L-dihydroxyphenylalanine/carbidopa and selegiline. Mov Disord 1995;10:349-51.
-
(1995)
Mov Disord
, vol.10
, pp. 349-351
-
-
Davis, T.L.1
Roznoski, M.2
Burns, R.S.3
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