A new isoquinolinone derivative with noble vasorelaxation activity

Pharmacology

Volumn 67, Issue 4, 2003, Pages 202-210

  Lin, Chia Hsien ^a   Lin, Mei Shan ^a,b   Lin, Ying Hsiu ^a   Chen, I Ming ^a   Lin, Pen Rong ^a   Cheng, Chen Yu ^a   Tsai, Ming Cheng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Acetylcholine; Aorta; BDPBI (7 bromo 1,4 dihydro 2 phenyl 4,4 bis(4 pyridinylmethyl)2H isoquinolin 3 one dihydrochloride); Endothelium; Histamine; Smooth muscle; Vasorelaxant

Indexed keywords

4 CHROMANONE DERIVATIVE; 7 BROMO 1,4 DIHYDRO 2 PHENYL 4,4 BIS(4 PYRIDINYLMETHYL) 2H ISOQUINOLIN 3 ONE; ACETYLCHOLINE; ACETYLSALICYLIC ACID; ADRENERGIC RECEPTOR BLOCKING AGENT; ATROPINE; CHLORPHENIRAMINE MALEATE; DIPHENHYDRAMINE; HISTAMINE H1 RECEPTOR AGONIST; HISTAMINE RECEPTOR; INDOMETACIN; ISOQUINOLINE DERIVATIVE; KETONE DERIVATIVE; N(G) NITROARGININE METHYL ESTER; PHENYLEPHRINE; PROPRANOLOL; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL TISSUE; AORTA; ARTICLE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTRACTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG FORMULATION; DRUG SCREENING; DRUG SYNTHESIS; ENDOTHELIUM CELL; GUINEA PIG; MALE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; TISSUE INJURY; TISSUE PREPARATION; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION;

ACETYLCHOLINE; ADRENERGIC ANTAGONISTS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AORTA, THORACIC; ASPIRIN; ATROPINE; CHLORPHENIRAMINE; CIMETIDINE; DIPHENHYDRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; GUINEA PIGS; HISTAMINE H1 ANTAGONISTS; HISTAMINE H2 ANTAGONISTS; INDOMETHACIN; ISOQUINOLINES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MUSCARINIC ANTAGONISTS; PHENYLEPHRINE; PROPRANOLOL; PYRIDINES; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS; YOHIMBINE;

EID: 0037217485     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000068402     Document Type: Article

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