NO release and the opening of K(ATP)/+ channels mediate vasodilator responses to histamine in the cat

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 2 42-2, 1997, Pages

  Champion, Hunter C ^a   Kadowitz, Philip J ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine 5' triphosphate sensitive potassium channel; Endothelium derived relaxing factor; Nitric oxide; Tetraethylammonium

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA METHYLHISTAMINE; DIMAPRIT; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR; MEPYRAMINE; NITRIC OXIDE; POTASSIUM CHANNEL; POTASSIUM ION;

ALLERGIC REACTION; ANIMAL EXPERIMENT; ARTICLE; CAT; CONTROLLED STUDY; HISTAMINE RELEASE; INFLAMMATION; LIMB PERFUSION; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; VASCULAR SMOOTH MUSCLE;

EID: 33751293866     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.2.h928     Document Type: Article

References (9)

1. +): a functional approach to separating EDHF- and EDNO-related mechanisms in perfused rat mesenteric arterial bed. J. Cardiovasc. Pharmacol. 21: 423-429, 1993.
2. Bellan, J. A., D. B. McNamara, and P. J. Kadowitz. Differential effects of nitric oxide synthesis inhibitor on vascular resistance and responses to acetylcholine in the cat. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H45-H56, 1993.
3. 3 vasodilator mechanisms in the guinea pig ileum. Gastroenterology 108: 712-718, 1995.
4. Bhardwaj, R., and P. K. Moore. Endothelium-derived relaxing factor and the effects of acetylcholine and histamine on resistance blood vessels. Br. J. Pharmacol. 95: 835-843, 1988.
5. Bull, H. A., P. F. Courtney, M. H. A. Rustin, and P. M. Dowd. Characterization of histamine receptor sub-types regulation of prostacyclin release from human endothelial cells. Br. J. Pharmacol. 107: 276-281, 1992.
6. Champion, H. C., J. A. Santiago, W. A. Murphy, D. H. Coy, and P. J. Kadowitz. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R234-R242, 1997.
7. + channels contribute to vascular tone. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1135-H1141, 1994.
8. Feigen, L. P., B. M. Chapnick, J. E. Fleming, and P. J. Kadowitz. Prostaglandins: renal vascular responses to bradykinin, histamine, and nitroglycerin. Am. J. Physiol. 234 (Heart Circ. Physiol. 3): H496-H502, 1978.
9. Flynn, S. B., and D. A. A. Owen. Histamine receptors in peripheral vascular beds in the cat. Br. J. Pharmacol. 55: 181-188, 1975.