Upregulation of Na+ transporter abundances in response to chronic thiazide or loop diuretic treatment in rats

American Journal of Physiology - Renal Physiology

Volumn 284, Issue 1 53-1, 2003, Pages

  Na, Ki Young ^a   Oh, Yoon Kyu ^b   Han, Jin Suk ^a,f   Joo, Kwon Wook ^a   Lee, Jung Sang ^a   Earm, Jae Ho ^d   Knepper, Mark A ^e   Kim, Gheun Ho ^c  

^a Seoul National University Hospital   (South Korea)

^b Eulji University School of Medicine   (South Korea)

^c Hallym University   (South Korea)

^d Chungbuk National University   (South Korea)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f Seoul National University College of Medicine   (South Korea)

Author keywords

Collecting duct; Distal convoluted tubule; Epithelial sodium channel; Thiazide sensitive sodium chloride cotransporter

Indexed keywords

CARRIER PROTEIN; FUROSEMIDE; HYDROCHLOROTHIAZIDE; LOOP DIURETIC AGENT; POTASSIUM CHLORIDE; SODIUM CHANNEL; SODIUM CHLORIDE; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM TRANSPORTER; THIAZIDE DIURETIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIURESIS; DIURETIC ACTIVITY; DRUG EFFECT; DRUG INFUSION; FLUID INTAKE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; NATRIURESIS; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE ANALYSIS; RAT;

EID: 0037216270     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00227.2002     Document Type: Article

References (42)

1. +/Cl-cotransporter abundance: Role of aldosterone. J Am Soc Nephrol 12: 1335-1341, 2001.
2. + channel is made of three homologous subunits. Nature 367: 463-467, 1994.
3. 3H-metolazone. J Am Soc Nephrol 1: 91-98, 1990.
4. Costanzo LS. Mechanism of action of thiazide diuretics. Semin Nephrol 8: 234-241, 1988.
5. + channel in rabbit kidney. Pflügers Arch 438: 354-360, 1999.
6. Due C, Farman N, Canessa CM, Bonvalet JP, and Rossier BC. Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: Localization by in situ hybridization and immunocytochemistry. J Cell Biol 127: 1907-1921, 1994.
7. Ecelbarger CA, Kim GH, Terris J, Masilamani S, Mitchell C, Reyes I, Verbalis JG, and Knepper MA. Vasopressin-mediated regulation of epithelial sodium channel abundance in rat kidney. Am J Physiol Renal Physiol 279: F46-F53, 2000.
8. Ecelbarger CA, Terris J, Frindt G, Echevarria M, Marples D, Nielsen S, and Knepper MA. Aquaporin-3 water channel localization and regulation in rat kidney. Am J Physiol Renal Fluid Electrolyte Physiol 269: F663-F672, 1995.
9. +-2Cl- cotransporter, BSC-1. Am J Physiol Renal Fluid Electrolyte Physiol 271: F619-F628, 1996.
10. Ellison DH. Diuretic resistance: Physiology and therapeutics. Semin Nephrol 19: 581-597, 1999.
11. Ellison DH, Velazquez H, and Wright FS. Thiazide-sensitive sodium chloride cotransport in early distal tubule. Am J Physiol Renal Fluid Electrolyte Physiol 253: F546-F554, 1987.
12. Ellison DH, Velazquez H, and Wright FS. Adaptation of the distal convoluted tubule of the rat. Structural and functional effects of dietary salt intake and chronic diuretic infusion. J Clin Invest 83: 113-126, 1989.
13. 4-induced cirrhosis. Kidney Int 58: 216-228, 2000.
14. Garg LC and Narang N. Effects of hydrochlorothiazide on Na-K-ATPase activity along the rat nephron. Kidney Int 31: 918-922, 1987.
15. Garty H and Palmer LG. Epithelial sodium channels: Function, structure, and regulation. Physiol Rev 77: 359-396, 1997.
16. Hager H, Kwon TH, Vinnikova AK, Masilamani S, Brooks HL, Frøkiær J, Knepper MA, and Nielsen S. Immunocytochemical and immunoelectron microscopic localization of α-, β- and γ-ENaC in rat kidney. Am J Physiol Renal Physiol 280: F1093-F1106, 2001.
17. Kaissling B, Bachmann S, and Kriz W. Structural adaptation of the distal convoluted tubule to prolonged furosemide treatment. Am J Physiol Renal Fluid Electrolyte Physiol 248: F374-F381, 1985.
18. Kaissling B and Stanton BA. Adaptation of distal tubule and collecting duct to increased sodium delivery. I. Ultrastructure. Am J Physiol Renal Fluid Electrolyte Physiol 255: F1256-F1268, 1988.
19. Kim GH, Martin SW, Fernandez-Llama P, Masilamani S, Packer RK, and Knepper MA. Long-term-regulation of renal Na-dependent cotransporters and ENaC: Response to altered acid-base intake. Am J Physiol Renal Physiol 279: F459-F467, 2000.
20. Kim GH, Masilamani S, Turner R, Mitchell C, Wade JB, and Knepper MA. The thiazide-sensitive Na-Cl cotransporter is an aldosterone-induced protein. Proc Natl Acad Sci USA 95: 14552-14557, 1998.
21. Kwon TH, Frøkiær J, Fernandez-Llama P, Maunsbach AB, Knepper MA, and Nielsen S. Altered expression of Na transporters NHE-3, NaPi-II, Na-K-ATPase, BSC-1, and TSC in CRF rat kidneys. Am J Physiol Renal Physiol 277: F257-F270, 1999.
22. + transporters in rats with lithium-induced NDI. Am J Physiol Renal Physiol 279: F552-F564, 2000.
23. Loffing J, Le Hir M, and Kaissling B. Modulation of salt transport rate affects DNA synthesis in vivo in rat renal tubules. Kidney Int 47: 1615-1623, 1995.
24. Loffing J, Loffing-Cueni D, Hegyi I, Kaplan MR, Hebert SC, Le Hir M, and Kaissling B. Thiazide treatment of rats provokes apoptosis in distal tubule cells. Kidney Int 50: 1180-1190, 1996.
25. Loffing J, Zecevic M, Feraille E, Kaissling B, Asher C, Rossier BC, Firestone GL, Pearce D, and Verrey F. Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: Possible role of SGK Am J Physiol Renal Physiol 280: F675-F682, 2001.
26. Masilamani S, Kim GH, Mitchell C, Wade JB, and Knepper MA. Aldosterone-mediated regulation of ENaC α, β and γ subunit proteins in rat kidney. J Clin Invest 104: R19-R23, 1999.
27. May A, Puoti A, Gaeggeler HP, Horisberger JD, and Rossier BC. Early effect of aldosterone on the rate of synthesis of the epithelial sodium channel alpha subunit in A6 renal cells. J Am Soc Nephrol 8: 1813-1822, 1997.
28. Miyanoshita A, Terada M, and Endou H. Furosemide directly stimulates prostaglandin E2 production in the thick ascending limb of Henle's loop. J Pharmacol Exp Ther 251: 1155-1159, 1989.
29. Morsing P, Velazquez H, Wright FS, and Ellison DH. Adaptation of distal convoluted tubule of rats. II. Effects of chronic thiazide infusion. Am J Physiol Renal Fluid Electrolyte Physiol 261: F137-F143, 1991.
30. Nejsum LN, Kwon TH, Marples D, Flyvbjerg A, Knepper MA, Frøkiær J, and Nielsen S. Compensatory increase in AQP2, p-AQP2, and AQP3 expression in rats with diabetes mellitus. Am J Physiol Renal Physiol 280: F715-F726, 2001.
31. Nicco C, Wittner M, DiStefano A, Jounier S, Bankir L, and Bouby N. Chronic exposure to vasopressin upregulates ENaC and sodium transport in the rat renal collecting duct and lung. Hypertension 38: 1143-1149, 2001.
32. Nielsen S, DiGiovanni SR, Christensen EI, Knepper MA, and Harris HW. Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney. Proc Natl Acad Sci USA 90: 11663-11667, 1993.
33. Praetorius HA and Spring KR. Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 184: 71-79, 2001.
34. Reeves WB and Molony DA. The physiology of loop diuretic action. Semin Nephrol 8: 225-233, 1988.
35. Rokaw MD, Wang JM, Edinger RS, Weisz OA, Hui D, Middleton P, Shlyonsky V, Berdiev BK, Ismailov I, Eaton DC, Benos DJ, and Johnson JP. Carboxylmethylation of the beta subunit of xENaC regulates channel activity. J Biol Chem 273:28746-28751, 1998.
36. Rossier BC, Canessa CM, Schild L, and Horisberger JD. Epithelial sodium channels. Curr Opin Nephrol Hypertens 3: 487-496, 1994.
37. +-ATPase with furosemide administration. Am J Physiol Renal Fluid Electrolyte Physiol 252: F910-F915, 1987.
38. + transport. Am J Physiol Renal Fluid Electrolyte Physiol 255: F1269-F1275, 1988.
39. Stokes JB and Sigmund RD. Regulation of rENaC mRNA by dietary NaCl and steroids: Organ, tissue, and steroid heterogeneity. Am J Physiol Cell Physiol 274: C1699-C1707, 1998.
40. Terris J, Ecelbarger CA, Nielsen S, and Knepper MA. Long-term regulation of four renal aquaporins in rats. Am J Physiol Renal Fluid Electrolyte Physiol 271: F414-F422, 1996.
41. Weisz OA, Wang JM, Edinger RS, and Johnson JP. Noncoordinate regulation of endogenous epithelial sodium channel (ENaC) subunit expression at the apical membrane of A6 cells in response to various transporting conditions. J Biol Chem 275: 39886-39893, 2000.
42. Wilcox CS, Deng X, and Welch WJ. NO generation and action during changes in salt intake: Roles of nNOS and macula densa. Am J Physiol Regul Integr Comp Physiol 274: R1588-R1593, 1998.