Comparison of 99mTc-mercaptoacetyltriglycine and [131I]-o-iodohippurate elimination in perfused rat kidney

Nuclear Medicine and Biology

Volumn 30, Issue 1, 2003, Pages 45-49

  Trejtnar, Frantisek ^a   Laznicek, Milan ^a   Laznickova, Alice ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

99mTc mercaptoacetyltriglycine; 131I o iodohippurate; Perfused rat kidney; Renal handling

Indexed keywords

IODOHIPPURATE SODIUM I 131; MERTIATIDE TC 99M; DIAGNOSTIC AGENT; IODOHIPPURIC ACID; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ELIMINATION; DRUG INFUSION; DRUG PROTEIN BINDING; DRUG STABILITY; KIDNEY CLEARANCE; KIDNEY PERFUSION; KIDNEY TUBULE EXCRETION; MALE; NONHUMAN; RADIODIAGNOSIS; RAT; URINARY EXCRETION; ANIMAL; COMPARATIVE STUDY; EVALUATION; INTRAARTERIAL DRUG ADMINISTRATION; KIDNEY; KIDNEY SCINTISCANNING; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PERFUSION; SCINTISCANNING; WISTAR RAT;

ANIMALS; INFUSIONS, INTRA-ARTERIAL; IODINE RADIOISOTOPES; IODOHIPPURIC ACID; KIDNEY; MALE; METABOLIC CLEARANCE RATE; PERFUSION; RADIOISOTOPE RENOGRAPHY; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; TECHNETIUM TC 99M MERTIATIDE;

EID: 0037213386     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(02)00377-3     Document Type: Article

References (20)

1. Besseghir K., Roch-Ramel F. Renal excretion of drugs and other xenobiotics. Renal Physiol. 10:1987;221-241.
2. Bubeck B., Brandau W., Weber E., Kuble T., Parekh N., Georgi P. Pharmacokinetics of technetium-99m-MAG3 in humans. J Nucl Med. 31:1990;1285-1293.
3. Burckhardt G., Bahn A., Wolff N.A. Molecular physiology of renal p-aminohippurate secretion. News Physiol Sci. 16:2001;114-118.
4. Coveney J.R., Robbins M.S. Comparison of technetium-99m MAG3 kit with HPLC-purified technetium-99m MAG3 and OIH in rats. J Nucl Med. 28:1987;1881-1887.
5. 99mTc-labeled tubular agents. J Nucl Med. 41:2000;2077-2082.
6. 99mTc renal tubular function agents current status . Semin Nucl Med. 20:1990;28-40.
7. 99mTc renal tubular function agent, Semin . Nucl Med. 22:1992;61-73.
8. Fritzberg A.R., Kasina S., Eshima D., Johnson D.L. Synthesis and biological evaluation of technetium-99m-MAG 3 as a hippuran replacement. J Nucl Med. 27:1986;111-116.
9. Herzog K.M., Deutsch E., Deutsch K., Silberstein E.B., Sarangarajan R., Cacini W. Synthesis and renal excretion of technetium-99m-labeled organic cations. J Nucl Med. 33:1992;2190-2195.
10. Heyrovsky A. A new method for the determination of inulin in plasma and urine. Clin Chim Acta. 1:1956;470-474.
11. Kabasakal L., Turoglu H.T., Onsel C., Ozker K., Uslu I., Atay S., Cansiz T., Sonmezoglu K., Altiok E., Isitman A.T. Clinical comparison of technetium-99m-EC, technetium-99m-MAG3 and iodine-131-OIH in renal disorders. J Nucl Med. 36:1995;224-228.
12. Lee L., Smith D.E. Renal excretion and metabolism of p-aminohippurate in the isolated perfused rat kidney. Pharm Res. 5:1988;745-747.
13. Laznickova A., Laznicek M., Kvetina J., Drobnik J. Pharmacokinetics and plasma protein binding of two platinum cytostatics CHIP and CBDCA in rats. Cancer Chemother Pharmacol. 17:1986;133-136.
14. McAfee J.G., Grossman Z.D., Gagne G.R. Comparison of renal extraction efficiencies for radioactive agents in the normal dog. J Nucl Med. 22:1981;333-338.
15. Miura K., Goldstein R.S., Pasini D.A., Hook J.B. Cisplatin nephrotoxicity role of filtration and tubular transport of cisplatin in isolated perfused kidney . Toxicology. 44:1987;147-158.
16. Müller-Surr R., Müller-Surr C. Renal and extrarenal handling of a new imaging compound (99m-Tc-MAG-3) in the rat. Eur J Nucl Med. 12:1986;438-442.
17. Ross C.R., Holohan P.D. Transport of organic anions and cations in isolated renal plasma membranes. Annu Rev Pharmacol Toxicol. 23:1983;65-85.
18. 99mTc-MAG3 - a new renal imaging agent Preliminary results in patients . Eur J Nucl Med. 12:1987;510-514.
19. Taylor A., Eshima D., Fritzberg A.R., Christian P.E., Kasina S. Comparison of iodine-131 OIH and technetium-99m MAG3 renal imaging in volunteers. J Nucl Med. 27:1986;795-803.
20. Van R.A.M.H., Masereeuw R., Russel F.G.M. Molecular pharmacology of renal anion transporters. Am J Renal Physiol. 279:2000;F216-F232.