Parallel synthesis of benzoxazoles via microwave-assisted dielectric heating

Tetrahedron Letters

Volumn 44, Issue 1, 2003, Pages 175-178

  Pottorf, Richard S ^a   Chadha, Naresh K ^a   Katkevics, Martins ^b   Ozola, Vita ^b   Suna, Edgars ^b   Ghane, Hadi ^c   Regberg, Tor ^c   Player, Mark R ^a  

^a JOHNSON AND JOHNSON   (United States)

^b LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

^c Personal Chemistry AB   (Sweden)

Author keywords

Benzoxazole; Microwave; Parallel synthesis

Indexed keywords

2 (2 BROMOPHENYL) 5 NITROBENZOXAZOLE; 2 (3,4,5 TRIMETHOXYPHENYL)BENZOXAZOLE; 2 (4 BROMOPHENYL)BENZOXAZOLE; 2 THIOPHEN 2 YLNAPHTHO[2,3 D]OXAZOLE; 6 (1,1 DIMETHYLPROPYL) 2 (4 NITROPHENYL)BENZOXAZOLE; BENZOXAZOLE DERIVATIVE; BIPHENYL 4 YL 4 METHYLBENZOXAZOLE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; HEATING; METHODOLOGY; MICROWAVE RADIATION;

EID: 0037213011     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02495-4     Document Type: Article

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10. 3) δ 8.55 (dd, J=2.2, 0.7 Hz, 1H), 8.37 (dd, J=8.8, 2.2 Hz, 1H), 8.16 (dd, J=7.6 2.0 Hz, 1H), 7.95 (d, J=8.8 Hz, 1H), 7.83 (dd, J=7.6, 1.6 Hz, 1H), 7.53 (ddd, J=7.6, 7.6, 1.6 Hz, 1H), 7.44 (ddd, J=7.6, 7.6, 2.0 Hz, 1H).