Allelic loss of chromosome 2 in human oral squamous cell carcinoma: Correlation with lymph node metastasis

Oral Oncology

Volumn 39, Issue 1, 2003, Pages 64-68

  Yamamoto, Nobuharu ^a,b   Mizoe, Jun Etsu ^a   Numasawa, Hideyuki ^b   Yokoe, Hidetaka ^c   Uzawa, Katsuhiro ^d   Shibahara, Takahiko ^b   Tsujii, Hirohiko ^a   Noma, Hiroyasu ^b   Tanzawa, Hideki ^c,d  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b TOKYO DENTAL COLLEGE   (Japan)

^c CHIBA UNIVERSITY HOSPITAL   (Japan)

^d CHIBA UNIVERSITY   (Japan)

Author keywords

Chromosome 2; Loss of heterozygosity; Metastasis; Oral squamous cell carcinoma; Tumor suppressor gene

Indexed keywords

ALLELE; ARTICLE; CANCER DIAGNOSIS; CANCER GROWTH; CARCINOGENESIS; CHROMOSOME 2; CHROMOSOME 2Q; CHROMOSOME ARM; CHROMOSOME DELETION; CHROMOSOME MAP; CLINICAL ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE LOCATION; GENE LOCUS; GENE SEQUENCE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MOUTH CARCINOMA; POLYMERASE CHAIN REACTION; POLYMORPHIC LOCUS; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

CARCINOMA, SQUAMOUS CELL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 2; GENE DELETION; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHATIC METASTASIS; MICROSATELLITE REPEATS; MOUTH NEOPLASMS;

EID: 0037210611     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-8375(02)00025-8     Document Type: Article

References (28)

1. Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 61:1990;759-767.
2. Marshall C.J. Tumor suppressor genes. Cell. 64:1991;313-326.
3. Friend S.H., Horwitz J.M., Gerber M.R., Wang X.F., Bogenmann E., Li F.P.et al. Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the wequence and its encoded protein. Proc Natl Acad Sci USA. 84:1987;9059-9063.
4. Ohta M., Inoue H., Cotticelli M.G., Kastury K., Baffa R., Palazzo J.et al. The FHIT gene, spanning the chromosome 3pl 4.2 fragile site and renal carcinoma-associated t(3,-8) breakpoint, is abnormal in digestive tract cancers. Cell. 84:1996;587-597.
5. Takita J., Hayashi Y., Kohno T., Shiseki M., Yamaguchi N., Hanada R.et al. Allelotype of neuroblastoma. Oncogene. 11:1995;1829-1834.
6. Williams S.T., Douglas W.S., Zahid K., Doris J.T., Samuel A.W. Jr., Paul J.G. Allelotype of follicular thyroid carcinomas reveals genetic instability consistent with frequent nondisjunctional chromosomal loss. Genes Chromosomes and Cancer. 19:1997;43-51.
7. Otsuka T., Kohno T., Mori M., Noguchi M., Hirohashi S., Yokota J. Deletion mapping of chromosome 2 in human lung carcinoma. Genes Chromosomes and Cancer. 16:1996;113-119.
8. Nishizuka S., Tamura G., Terashima M., Satodate R. Loss of heterozygosity during the development and progression of differentiated adenocarcinoma of the stomach. J Pathology. 185:1998;38-43.
9. International Histological Classification of Tumours, Histological Typing of Oral and Oropharyngeal Tumours, 4. 1971;WHO, Geneva.
10. TNM classtfication of malignant tumours. 4th ed. 1987;Springer, Berlin.
11. Uzawa K., Yoshida H., Suzuki H., Tanzawa H., Shimazaki J., Seino S.et al. Abnormalities of the adenomatous polyposis coli gene in human oral squamous-cell carcinoma. Int J Cancer. 58:1994;814-817.
12. Uzawa K., Suzuki H., Komoya A., Nakanishi H., Ogawara K., Tanzawa H.et al. Evidence for two distinct tumor-suppressor gene loci on the long arm of chromosome 11 in human oral cancer. Int J Cancer. 67:1996;510-514.
13. Ogawara K., Uzawa K., Nakanishi H., Yokoe H., Wang X.L., Tanzawa H.et al. Frequent microsatellite instability in oral cancer. Oncol Rep. 4:1997;161-165.
14. Partridge M., Emilion G., Langdon J.D. LOH at 3p correlates with a poor survival in oral squamous cell carcinoma. Br J Cancer. 73:1996;366-371.
15. Uzawa N., Akanuma D., Negishi A., Amagasa T., Yoshida M. Loss of heterozygosity on the short arm of chromosome 3 in oral squamous cell carcinomas: Relationship between loss of heterozygosity on 3p25-pter region and clinical and histological features. Jpn J Oral Maxillofac Surg. 46:2000;455-461.
16. Wang X.L., Uzawa K., Imai F.L., Tanzawa H. Localization of a novel tumor suppressor gene associated with human oral cancer on chromosome 4q25. Oncogene. 18:1999;823-825.
17. Wang X.L., Uzawa K., Nakanishi H., Tanzawa H., Sato K. Allelic imbalance on the long arm of chromosome 5 in oral squamous cell carcinoma. Int J Oncol. 10:1997;535-538.
18. Wang X.L., Uzawa K., Miyakawa A., Shiiba M., Watanabe T., Sato T.et al. Localization of a tumour-suppressor gene associated with human oral cancer on chromosome 7q31.1. Int J Cancer. 75:1998;671-674.
19. Ono K., Miyakawa A., Fukuda M., Shiiba M., Uzawa K., Watanabe T.et al. Allelic loss on the short arm of chromosome 8 in oral squamous cell carcinoma. Oncol Rep. 6:1999;785-789.
20. Nakanishi H., Wang X.L., Imai F.L., Kato J., Shiiba M., Miya T., Imai Y.et al. Localization of a novel tumor suppressor gene loci on chromosome 9p21-22 in oral cancer. Anticancer Res. 19:1999;29-34.
21. Yamashita Y., Miyakawa A., Mochida Y., Aisaki K., Yama M., Shiiba M.et al. Genetic aberration on chromosome 10 in human oral squamous cell carcinoma. Int J Oncol. 20:2002;595-598.
22. Uzawa K., Suzuki H., Komiya A., Nakanishi H., Ogawara K., Tanzawa H.et al. Evidence for two distinct tumor-suppressor gene loci on the long arm of chromosome 11 in human oral cancer. Int J Cancer. 67:1996;510-514.
23. Ogawara K., Miyakawa A., Shiiba M., Uzawa K., Watanabe T., Wang X.L.et al. Allelic loss of chromosome 13q14.3 in human oral cancer: correlation with lymph node metastasis. Int J Cancer. 79:1998;312-317.
24. Watanabe T., Wang X.L., Miyakawa A., Shiiba M., Imai Y., Sato T.et al. Mutational state of tumor suppressor genes (DCC, DPC4) and alteration on chromosome 18q21 in human oral cancer. Int J Oncol. 11:1997;1287-1290.
25. Imai F.L., Uzawa K., Miyakawa A., Shiiba M., Tanzawa H. A detailed deletion map of chromosome 20 in human oral squamous cell carcinoma. Int J Molecular Medicine. 7:2001;43-47.
26. Yamamoto N., Uzawa K., Miya T., Watanabe T., Yokoe H., Shibahara T.et al. Frequent allelic loss/imbalance on the long arm of chromosome 21 in oral cancer: Evidence for three distinct tumor suppressor gene loci. Oncol Rep. 6:1999;1223-1227.
27. Miyakawa A., Wang X.L., Nakanishi H., Imai F.L., Shiiba M., Miya T.et al. Allelic loss on chromosome 22 in oral cancer: possibility of the existence of a tumor suppressor gene on 22q13. Int J Oncol. 13:1998;705-709.
28. David T.R., Timothy C.B., Joan B., Bastiaan de Boer Cecily M., Davidson J.A., Gavin R.T. Loss of heterozygosity on chromosome 2q: possibly a poor prognostic factor in head and neck cancer. Head and Neck. 20:1998;404-410.