Opposing changes of trimeric G protein levels during ontogenetic development of rat brain

Developmental Brain Research

Volumn 133, Issue 1, 2002, Pages 57-67

  Ihnatovych, Ivanna ^a   Novotny, Jiri ^a,b   Haugvicova, Renata ^a   Bourova, Lenka ^a,b   Mareš, Pavel ^a   Svoboda, Petr ^a,b  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Development; Rat brain; Trimeric G protein

Indexed keywords

BRAIN PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PEPTIDE ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN SUBUNIT; UREA;

ALPHA CHAIN; ANIMAL TISSUE; ARTICLE; BETA CHAIN; BIRTH; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN MATURATION; CONTROLLED STUDY; HIPPOCAMPUS; HYPOPHYSIS; IMMUNOBLOTTING; MALE; NONHUMAN; ONTOGENY; PERINATAL PERIOD; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN VARIANT; RAT; THALAMUS; TISSUE DISTRIBUTION;

AGING; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL DIFFERENTIATION; DOWN-REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GTP-BINDING PROTEINS; HETEROTRIMERIC GTP-BINDING PROTEINS; MALE; NEUROGLIA; NEURONS; PROTO-ONCOGENE PROTEINS; RATS; RATS, WISTAR; UP-REGULATION;

ANIMALIA;

EID: 0037204036     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(01)00322-4     Document Type: Article

References (45)

1. Immunoassay for the βγ subunits of GTP-binding proteins and their regional distribution in bovine brain
2. Structural heterogeneity of membrane receptors and GTP-binding proteins and its functional consequences for signal transduction
3. sαS
4. Human cDNA clones for four species of GαS signal transduction protein
5. Undernutrition and the developing brain
6. Molecular basis for interactions of G protein βγ subunits with effectors
7. Multiple Gi protein subtypes regulate a single effector mechanism
8. Distinct roles for Gαi2, Gαi3, and Gβγ in modulation of forskolin- or Gs-mediated cAMP accumulation and calcium mobilization by dopamine D2S receptors
9. Use of specific antibodies to quantitate the guanine nucleotide-binding protein Go in brain
10. Purification of heterotrimeric GTP-binding proteins from brain: Identification of a novel form of Go
11. Functional and structural complexity of signal transduction via G-protein-coupled receptors
12. Distinct biochemical properties of the native members of the G12 G-protein subfamily. Characterization of Gα12 purified from rat brain
13. Purification of the G-protein G13 from rat brain membranes
14. Structure and function of proteins in G-protein-coupled signal transfer
15. Role of subunit diversity in signaling by heterotrimeric G proteins
16. 2-adrenoceptor coupling with GTP-binding proteins in the rat telencephalon
17. The role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel
18. Signal-transducing G proteins and antidepressant drugs: Evidence for modulation of α subunit gene expression in rat brain
19. The regulation of adenylyl cyclase by receptor-operated G proteins
20. Effect of thyroid deficiency on Goα-subunit isoforms in developing rat cerebral cortex
21. Sites for Gα binding on the G protein β subunit overlap with sites for regulation of phospholipase Cβ and adenylyl cyclase
22. Protein measurement with Folin phenol reagent
23. Epileptic phenomena in the immature brain
24. Immunological probes and the identification of guanine nucleotide binding proteins
25. Regional distribution and quantitative measurement of the phosphoinositidase C-linked guanine nucleotide binding proteins G11α and Gq α in rat brain
26. Guanine-nucleotide-binding proteins expressed in rat white adipose tissue. Identification of both mRNAs and proteins corresponding to Gi1, Gi2 and Gi3
27. Widespread distribution of Gqα/G11α detected immunologically by an antipeptide antiserum directed against the predicted C-terminal decapeptide
28. High expression of the γ5 isoform of G protein in neuroepithelial cells and its replacement of the γ2 isoform during neuronal differentiation in the rat brain
29. Physiological regulation of G protein-linked signaling
30. Agonist activation of transfected human M1 muscarinic acetylcholine receptors in CHO cells results in down-regulation of both the receptor and the α subunit of the G protein Gq
31. Identification of two distinct isoforms of the guanine nucleotide binding protein Go in neuroblastoma X glioma hybrid cells: Independent regulation during cyclic AMP-induced differentiation
32. Chromatographic resolution and immunologic identification of the α40 and α41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain
33. Isoproterenol-induced subcellular redistribution of G protein β-subunits in S49 lymphoma cells demonstrated by a novel competitive ELISA
34. The long (Gsα-L) and short (Gsα-S) variants of the stimulatory guanine nucleotide-binding protein. Do they behave in an identical way?
35. Multiple mechanisms of receptor-G protein signaling specificity
36. Developmental changes in Gs and G(olf) proteins and adenylyl cyclases in mouse brain membranes
37. Developmental expression of G proteins that differentially modulate adenylyl cyclase activity in mouse brain
38. Diversity of G proteins in signal transduction
39. Different functional forms of G-protein βγ-subunits, βγ-I and βγ-II, in bovine brain
40. Agonist-induced transfer of the α subunits of the guanine nucleotide-binding regulatory proteins Gq and G11 and of muscarinic m1 acetylcholine receptors from plasma membranes to a light-vesicular membrane fraction
41. Cold-induced reduction in Giα proteins in brown adipose tissue. Effects of cellular hypersensitization to noradrenaline caused by pertussis-toxin treatment
42. Regulation of mammalian adenylyl cyclases by G-protein α and βγ subunits
43. Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases
44. Differential ontogenetic appearance and regulation of stimulatory G protein isoforms in rat cerebral cortex by thyroid hormone deficiency
45. Maturational and aging effects on guanine nucleotide binding protein immunoreactivity in human brain