Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate

Inorganic Chemistry

Volumn 41, Issue 26, 2002, Pages 7159-7169

  Barry, Colin G ^a   Turney, Elizabeth C ^a   Day, Cynthia S ^a   Saluta, Gilda ^b   Kucera, Gregory L ^b   Bierbach, Ulrich ^a  

^a WAKE FOREST UNIVERSITY   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (ACRIDINE 9 YLAMINO)ETHYL] 1,3,3 TRIMETHYLTHIOUREA HYDROTRIFLATE; ACRIDINE DERIVATIVE; AMINE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; METAL; PENTAAMMINE (1,1,3,3 TETRAMETHYLTHIOUREA)RHODIUM TRIFLATE; PENTAAMMINE [9 [2 (TRIMETHYLTHIOUREIDO)ETHYLAMINO]ACRIDIUNIUM]RHODIUM TRIFLATE; PLATINUM; RHODIUM AMMINE DERIVATIVE; RHODIUM COMPLEX; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; ARTICLE; BINDING AFFINITY; BIOLOGY; CYTOTOXICITY; DNA BINDING; DNA DAMAGE; DRUG SYNTHESIS; GENE TARGETING; PHOTOCHEMISTRY; PHOTOLYSIS; PHOTOSTIMULATION; PHOTOTOXICITY; PROTON NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET SPECTROSCOPY; X RAY ANALYSIS;

ACRIDINES; ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CHEMISTRY; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORESIS, AGAR GEL; ESCHERICHIA COLI; HUMANS; INTERCALATING AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMISTRY; RHODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; THIOUREA; TUMOR CELLS, CULTURED;

EID: 0037203147     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic025744n     Document Type: Article

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