Noninvasive monitoring of local drug release in a rabbit radiofrequency (RF) ablation model using X-ray computed tomography

Journal of Controlled Release

Volumn 83, Issue 3, 2002, Pages 415-425

  Szymanski Exner, Agata ^a   Stowe, Nicholas T ^b   Lazebnik, Roee S ^a   Salem, Kyle ^a   Wilson, David L ^a   Haaga, John R ^c   Gao, Jinming ^a,c  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Iohexol; Local drug delivery; Pharmacokinetics; Rabbit model; Radiofrequency ablation; X ray CT

Indexed keywords

BUFFER; IOHEXOL; PHOSPHATE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATHETER ABLATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG MONITORING; DRUG RELEASE; IN VITRO STUDY; LIVER; LIVER INJURY; MALE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RABBIT; RADIOFREQUENCY RADIATION; X RAY;

ANIMALS; CATHETER ABLATION; DRUG DELIVERY SYSTEMS; IOHEXOL; LIVER; MALE; RABBITS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0037202214     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(02)00216-X     Document Type: Article

References (35)

1. Becker G.J. 2000 RSNA annual oration in diagnostic radiology: the future of interventional radiology. Radiology. 220:2001;281-292.
2. Ray C.E. Jr. Interventional radiology in cancer patients. Am. Fam. Physician. 62:2000;95-102.
3. Vogl T.J., Muller P.K., Mack M.G., Straub R., Engelmann K., Neuhaus P. Liver metastases: interventional therapeutic techniques and results. Eur. Radiol. 9:1999;675-684.
4. Montgomery M.L., Sullivan J.P. Advances in interventional radiology. The search for less invasive management sparks new approaches. Postgrad. Med. 109:2001;93-104.
5. August D.A., Sugarbaker P.H., Ottow R.T. Hepatic resection of colorectal metastases. Ann. Surg. 201:1998;210-218.
6. Rossi S., Buscarini E., Garbagnati F., Di Stasi M., Quaretti P., Rago M., Zangrandi A., Andreola S., Silverman D., Buscarini L. Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. AJR Am. J. Roentgenol. 170:(4):1998;1015-1022.
7. Rossi S., Di Stasi M., Buscarini E., Quaretti P., Garbagnati F., Squassante L., Paties C.T., Silverman D.E., Buscarini L. Percutaneous RF interstitial thermal ablation in the treatment of hepatic cancer. AJR Am. J. Roentgenol. 167:(3):1996;759-768.
8. Jiao L.R., Hansen P.D., Havlik R., Mitry R.R., Pignatelli M., Habib N. Clinical short-term results of radiofrequency ablation in primary and secondary liver tumors. Am. J. Surg. 177:(4):1999;303-306.
9. Lewin J.S., Connell C.F., Duerk J., Chung Y., Clampitt M., Spisak J., Gazelle G., Haaga J. Interactive MRI-guided radiofrequency interstitial thermal ablation of abdominal tumors: clinical trial for evaluation of safety and feasibility. J. Magn. Reson. Imaging. 8:1998;40-47.
10. Dodd G.D., Soulen M.C., Kane R.A., Livraghi T., Lees W.R., Yamashita Y., Gillams A.R., Karahan O.I., Rhim H. Minimally invasive treatment of malignant hepatic tumors: at the threshold of a major breakthrough. Radiographics. 20:(1):2000;9-27.
11. Goldberg S.N. Radiofrequency tumor ablation: principles and techniques. Eur. J. Ultrasound. 13:2001;129-147.
12. Goldberg S.N., Gazelle G.S., Compton C.C., Mueller P.R., Tanabe K.K. Treatment of intrahepatic malignancy with radiofrequency ablation: radiologic-pathologic correlation. Cancer. 88:2000;2452-2463.
13. Livraghi T., Lazzaroni S., Meloni F. Radiofrequency thermal ablation of hepatocellular Carcinoma. Eur. J. Ultrasound. 13:2001;159-166.
14. Yamasaki T., Kurokawa F., Shirahashi H., Kusano N., Hironaka K., Okita K. Percutaneous radiofrequency ablation therapy with combined angiography and computed tomography assistance for patients with hepatocellular carcinoma. Cancer. 91:2001;1342-1348.
15. Bartolozzi C., Crocetti L., Cioni D., Donati F.M., Lencioni R. Assessment of therapeutic effect of liver tumor ablation procedures. Hepatogastroenterology. 48:(38):2001;352-358.
16. Cioni D., Lencioni R., Bartolozzi C. Percutaneous ablation of liver malignancies: imaging evaluation of treatment response. Eur. J. Ultrasound. 13:(2):2001;73-93.
17. Lencioni R., Goletti O., Armillotta N., Paolicchi A., Moretti M., Cioni D., Donati F., Cicorelli A., Ricci S., Carrai M., Conte P.F., Cavina E., Bartolozzi C. Radio-frequency thermal ablation of liver metastases with a cooled-tip electrode needle: results of a pilot clinical trial. Eur. Radiol. 8:(7):1998;1205-1211.
18. Francica G., Marone G. Ultrasound-guided percutaneous treatment of hepatocellular carcinoma by radiofrequency hyperthermia with a 'cooled-tip needle'. A preliminary clinical experience. Eur. J. Ultrasound. 9:(2):1999;145-153.
19. Buscarini L., Rossi S. Technology for radiofrequency thermal ablation of liver tumors. Semin. Laparosc. Surg. 4:(2):1997;96-110.
20. Qian F., Nasongkla N., Gao J. Membrane-encased polymer millirods for sustained release of 5-fluorouracil. J. Biomed. Mater. Res. 61:2002;203-211.
21. Gao J., Qian F., Szymanski-Exner A., Stowe N., Haaga J. In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers. J. Biomed. Mater. Res. 62:2002;308-314.
22. Saltzman M. Drug Delivery: Engineering Principles for Drug Therapy. 2001;235-315 Oxford University Press.
23. Fung L.K., Shin M., Tyler B., Brem H., Saltzman W.M. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Pharm. Res. 13:(5):1996;671-682.
24. Strasser J.F., Fung L.K., Eller S., Grossman S.A., Saltzman W.M. Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants. J. Pharmacol. Exp. Ther. 275:(3):1995;1647-1655.
25. Gutman R.L., Peacock G., Lu D.R. Targeted drug delivery for brain cancer treatment. J. Controlled Release. 65:(1-2):2000;31-41.
26. Brem H., Lawson H.C. The development of new brain tumor therapy utilizing the local and sustained delivery of chemotherapeutic agents from biodegradable polymers. Cancer. 86:(2):1999;325-330.
27. A. Szymanski-Exner, N.T. Stowe, K.A. Salem, R.E. Lazebnik, J.R. Haaga, D.L. Wilson, J. Gao, Noninvasive monitoring of local drug release using X-ray computed tomography: optimization and in vivo/in vitro validation, J. Pharm. Sci. (2002) (in press).
28. K.A. Salem, A. Szymanski-Exner, R.E. Lazebnik, M.S. Breen, J. Gao, D.L. Wilson, X-ray computed tomography methods for in vivo evaluation of local drug release systems, IEEE-Transact. Med. Imag. (2002) (in press).
29. Qian F., Szymanski A., Gao J. Fabrication and characterization of controlled release poly(D,L-lactide-co-glycolide) millirods. J. Biomed. Mater. Res. 55:(4):2001;512-522.
30. Merkle E.M., Boll D.T., Boaz T., Duerk J.L., Chung Y.C., Jacobs G.H., Varnes M.E., Lewin J.S. MRI-guided radiofrequency thermal ablation of implanted VX2 liver tumors in a rabbit model: demonstration of feasibility at 0.2 T. Magn. Reson. Med. 42:(1):1999;141-149.
31. R.S. Lazebnik, T.L. Lancaster, M.S. Breen, J.S. Lewin, D.L. Wilson, Volume registration using needle paths and point landmarks for evaluation of interventional MRI treatments, IEEE Transact. Med. Imag. (2001) (submitted for publications).
32. Lazebnik R.S., Lancaster T.L., Breen M.S., Nour S.G., Lewin J.S., Wilson D.L. Volume registration of interventional MRI data using needle paths and point landmarks. Proceedings of SPIE Medical Imaging 2002: Visualization, Display, and Image-Guided Procedures: 2002.
33. Jain R.A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials. 21:(23):2000;2475-2490.
34. Jain R.K. Delivery of molecular and cellular medicine to solid tumors. J. Controlled Release. 53:1998;49-67.
35. Au J.L., Jang S.H., Zheng J., Chen C., Song S., Hu L., Wientjes M.G. Determinants of drug delivery and transport to solid tumors. J. Controlled Release. 74:(1-3):2001;31-46.