The effect of parasympathetic postganglionic denervation on parotid salivary protein secretion in anaesthetized sheep

Autonomic Neuroscience: Basic and Clinical

Volumn 100, Issue 1-2, 2002, Pages 50-57

  Edwards, A V ^a   Titchen, D A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Autonomic nervous system; Denervation; Parotid gland

Indexed keywords

ACETYLCHOLINE; POTASSIUM; SALIVA PROTEIN; SODIUM; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC DENERVATION; CONTROLLED STUDY; FLOW RATE; NERVE TRANSECTION; NONHUMAN; PARASYMPATHETIC INNERVATION; PARASYMPATHETIC POSTGANGLIONIC DENERVATION; PAROTID GLAND; POSTGANGLIONIC NERVE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN SECRETION; SALIVATION; SHEEP; WEIGHT;

ACETYLCHOLINE; ANESTHESIA; ANIMALS; ANIMALS, NEWBORN; ATROPINE; CALCITONIN GENE-RELATED PEPTIDE; DRUG INTERACTIONS; ELECTRIC STIMULATION; INFUSIONS, INTRA-ARTERIAL; PARASYMPATHECTOMY; PARASYMPATHETIC NERVOUS SYSTEM; PARASYMPATHOLYTICS; PAROTID GLAND; POTASSIUM; PROTEINS; SALVIA; SHEEP; SODIUM; SYMPATHETIC NERVOUS SYSTEM; TIME FACTORS; VASOACTIVE INTESTINAL PEPTIDE; VASODILATOR AGENTS;

EID: 0037201184     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1566-0702(02)00148-0     Document Type: Article

References (35)

1. Anderson L.C., Garrett J.R., Proctor G.B. Advantages of burst stimulation for inducing sympathetic salivary secretion in rats. Q. J. Exp. Physiol. 73:1988;1025-1028.
2. Bernard C. Recherches experimentales sur les ganglions du grand sympathetique. C. R. Hebd. Seances Acad. Sci. 55:1862;341-350.
3. Bloom S.R., Edwards A.V., Garrett J.R. Effects of stimulating the sympathetic innervation in bursts on submandibular vascular and secretory function in cats. J. Physiol. (London). 393:1987;91-106.
4. Carr D.H., Davey M., Titchen D.A. Sympathetic and adrenergic effects on protein secretion from the parotid of the sheep. Case R.M., Lingard J.M., Young J.A. Secretion: Mechanisms and Control. 1984;219-222 Manchester Univ. Press, Manchester.
5. Edwards C.M.B., Edwards A.V. Release of vasoactive intestinal peptide (VIP) from the submandibular gland in anaesthetized sheep. J. Physiol. (London). 531P:2001;100.
6. Edwards A.V., Garrett J.R. Submandibular responses to stimulation of the sympathetic innervation following parasympathetic denervation in cats. J. Physiol. (London). 397:1988;421-431.
7. Edwards A.V., Titchen D.A. Synergism in the autonomic control of secretion of protein from the parotid gland of the sheep. J. Physiol. (London). 451:1992;1-15.
8. Edwards A.V., Titchen D.A. Effects of parasympathetic denervation on the parotid gland of anaesthetized sheep. J. Physiol. (London). 459:1993;197.
9. Edwards A.V., Titchen D.A. Autonomic control of protein production by the parotid gland of the sheep. Auton. Neurosci. Basic Clin. 100:2002;. (in press).
10. Edwards A.V., Garrett J.R., Proctor G.B. Effect of parasympathectomy on the protein composition of sympathetically evoked submandibular saliva of cats. J. Physiol. (London). 410:1989;43.
11. Edwards A.V., Garrett J.R., Proctor G.B. Interactions between the sympathetic and parasympathetic innervations to the submandibular gland of the anaesthetized cat. Exp. Physiol. 82:1997;697-708.
12. Ekström J., Tobin G. Protein secretion in salivary glands of cats in vivo and in vitro in response to vasoactive intestinal peptide. Acta Physiol. Scand. 140:1990;95-103.
13. Emmelin N. "Paralytic" secretion of saliva. An example of supersensitivity after denervation. Physiol. Rev. 32:1952;21-46.
14. Emmelin N., Jacobsohn D., Muren A. Effects of prolonged administration of atropine and pilocarpine on the submaxillary gland of the cat. Acta Physiol. Scand. 24:1951;128-143.
15. Fleming A.J., Macintosh F.C. The effect of sympathetic stimulation and of autonomic drugs on the paralytic submaxillary gland of the cat. Q. J. Exp. Physiol. 25:1935;207-212.
16. Hall H.D., Schneyer C.A. Salivary gland atrophy in rat induced by liquid diet. Proc. Soc. Exp. Biol. Med. 117:1964;789-793.
17. Hall H.D., Schneyer C.A. Role of autonomic pathways in disuse atrophy of rat parotid gland. Proc. Soc. Exp. Biol. Med. 143:1973;19-23.
18. Hall H.D., Schneyer C.A. Neural regulation of compensatory enlargement of the parotid gland of the rat. Cell Tissue Res. 187:1978;147-158.
19. Humphreys-Beher M.G., Zelles T., Maeda N., Purushotham K.R., Schneyer C.A. Cell surface galactosyltransferase acts as a general modulator of rat acinar cell proliferation. Mol. Cell. Biochem. 246:1990;1-11.
20. Kay R.N.B. Continuous and reflex secretion by the parotid gland in ruminants. J. Physiol. (London). 144:1958;463-475.
21. Kay R.N.B. The development of parotid salivary secretion in young goats. J. Physiol. (London). 150:1960;538-545.
22. McMillian M.K., Talamo B.R. Parasympathetic denervation increases responses to VIP in isolated rat parotid acini. Peptides. 10:1989;721-727.
23. Nilsson B.-O., Rosengren E., Ekström J. Effects of stimulation of the parasympathetic and sympathetic innervations in bursts on the syntheses of polyamines, DNA and protein in salivary glands of the rat: non-adrenergic, non-cholinergic responses. Acta Physiol. Scand. 143:1991;161-168.
24. Patterson J., Lloyd L.C., Titchen D.A. Secretory and structural changes in the parotid salivary gland of sheep and lambs after parasympathetic denervation. Q. J. Exp. Physiol. 60:1975;223-232.
25. Patterson J., Brightling P., Titchen D.A. β-adrenergic effects on composition of parotid salivary secretion of sheep on feeding. Q. J. Exp. Physiol. 67:1982;57-67.
26. Reid A.M., Titchen D.A. A comparison of the effects of vasoactive intestinal polypeptide on secretion from the submaxillary gland of the sheep and pig. Regulatory Pept. 20:1988;211-221.
27. Schneyer C.A. Mitosis induced in adult rat parotid following normal activity of the gland. Proc. Soc. Exp. Biol. Med. 134:1970;98-102.
28. Schneyer C.A., Hall H.D. Autonomic regulation of postnatal changes in cell number and size of rat parotid. Am. J. Physiol. 219:1970;1268-1272.
29. Schneyer C.A., Humphreys-Beher M. Inhibition if isoproterenol-induced DNA and RNA synthesis in the rat parotid gland and pancreas following removal of submandibular-sublingual glands. Cell Tissue Res. 256:1989;361-363.
30. Schneyer C.A., Humphreys-Beher M.G., Hall D.A. Inhibition of activity-induced parotid growth by submandibular gland ablation or autonomic denervation. Am. J. Physiol. 261:1991;G723-G727. (Gastrointest. Liver Physiol. 24).
31. Schneyer C.A., Humphreys-Beher M.G., Hall H.D., Jirakulsomchok D. Mitogenic activity of rat salivary glands after electrical stimulation of parasympathetic nerves. Am. J. Physiol. 264:1993;G935-G938. (Gastrointest. Liver Physiol. 27).
32. Thesleff P. An electrophysiological in-vivo study on the effects of nerve stimulation, drugs and denervation in the parotid gland of the rat. Acta Physiol. Scand. 136:1989;235-243.
33. Tobin G., Mirfendereski S., Åhström T., Ekström J. Fluid and protein secretion from ferret submandibular and parotid glands in response to sympathetic nerve stimulation or administration of sympathomimetics. Acta Physiol. Scand. 153:1995;231-241.
34. Wathuta E.M. The distribution of vasoactive intestinal polypeptide-like, substance P-like and bombesin-like immunoreactivity in the digestive system of the sheep. Q. J. Exp. Physiol. 71:1986;615-631.
35. Wilson A.D. The influence of diet on the development of parotid salivation and the rumen of the lamb. Aust. J. Agric. Res. 14:1963;226-238.