Development of androgen receptor and p75NTR mRNAs and peptides in the lumbar spinal cord of the gerbil

Developmental Brain Research

Volumn 137, Issue 2, 2002, Pages 101-114

  Scott Fraley, Gregory ^a   Ulibarri, Catherine ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Dihydrotestosterone; Dorsolateral nucleus; Estradiol; Spinal nucleus of the Bulbocavernosus; Testosterone

Indexed keywords

ANDROGEN RECEPTOR; MESSENGER RNA; NEUROTROPHIN RECEPTOR; PEPTIDE; PROTEIN P75; SEX HORMONE;

ANIMAL TISSUE; ARTICLE; CASTRATION; CONTROLLED STUDY; FEMALE; HORMONE ACTION; HORMONE SUBSTITUTION; IMMUNOREACTIVITY; LUMBAR SPINAL CORD; MALE; NEWBORN; NONHUMAN; PERINATAL DEVELOPMENT; PERINATAL PERIOD; PREPUBERTY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENTIATION; SPINAL CORD MOTONEURON;

AGING; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; ESTRADIOL; FEMALE; GERBILLINAE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR NEURONS; PEPTIDES; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, ANDROGEN; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER; SEX CHARACTERISTICS; SEX DIFFERENTIATION; SPINAL CORD; TESTOSTERONE;

GERBILLINAE;

EID: 0037199704     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(02)00412-1     Document Type: Article

References (64)

1. Abercrombie M. Estimation of nuclear population from microtome sections. Anat. Rec. 94:1946;239-247.
2. Al-Shamma H.A., Arnold A.P. Brain-derived neurotrophic factor regulates the expression of androgen receptors in perineal motoneurons. Proc. Natl. Acad. Sci. 94:1997;1-6.
3. Angerer L.M., Stoler M.H., Angerer R.C. In situ hybridization with RNA probes: an annotated recipe. Valentino K.L., Eberwine J.H., Barchas J.D., In Situ Hybridization. 1987;43-70 Oxford University Press.
4. Barbacid M. Nerve growth factor: a tale of two receptors. Oncogene. 8:1993;2033-2042.
5. Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Ann. Rev. Neurosci. 18:1995;223-253.
6. Breedlove S.M., Arnold A.P. Hormone accumulation in a sexually dimorphic motor nucleus of the rat spinal cord. Science. 210:1980;564-566.
7. Breedlove S.M., Arnold A.P. Sexually dimorphic motor nucleus in the rat lumbar spinal cord: response to adult hormone manipulations, absence in androgen-insensitive rats. Brain Res. 225:1981;297-307.
8. Breedlove S.M., Arnold A.P. Hormonal control of a developing neuromuscular system: I. Complete demasculinization of the male rat spinal nucleus of the bulbocavernosus using the anti-androgen flutamide. J. Neurosci. 3:1983;417-423.
9. Breedlove S.M., Arnold A.P. Hormonal control of a developing neuromuscular system: II. Sensitive periods for the androgen induced masculinization of the rat spinal nucleus of the bulbocavernosus. J. Neurosci. 3:1983;417-423.
10. Breedlove S.M. Androgen forms sexually dimorphic spinal nucleus by saving motoneurons from programmed death. Soc. Neurosci. Abstr. 10:1984;927.
11. Chao M.V. Neurotrophin receptors: A window into neuronal differentiation. Neuron. 9:1992;583-593.
12. Cihak R., Gutmann E., Hanzlikova V. Involution and hormone-induced persistence of the M. sphincter (levator) ani in female rats. J. Anat. 106:1970;93-110.
13. Commins D., Yahr P. Lesions of the sexually dimorphic area disrupt mating and scent marking in male gerbils. Brain Res. Bull. 13:1984;185-193.
14. Curtis R., Adryan K.M., Stark J.L., et al. Differential role of the low affinity neurotrophin receptor (p75) in the retrograde axonal transport of the neurotrophins. Neuron. 14:1995;1201-1211.
15. Dubrowski B., Filipini D. Neurobiological aspects of the pelvic floor muscles involved in defecation. Neurosci. Biobehav. Rev. 14:1990;157-168.
16. Dubrowsky R.T., Werner M.H., Castellino A.M., Chao M.V., Hannum Y.A. Activation of the sphingomyelin cycle pathway through the low-affinity neurotrophin receptor. Science. 265:1994;1596-1599.
17. Ernfors P., Hallbrook F., Ebeudal T., et al. Developmental and regional expression of b-nerve growth factor receptor mRNA in the chick and rat. Neuron. 1:1988;983-996.
18. Forger N., Breedlove S.M. Seasonal variation in mammalian striated muscle mass and motoneuron morphology. J. Neurobiol. 18:1987;155-165.
19. Fraley G.S., Kuenzel W.J. Immunocytochemical and histochemical analyses of gonadotrophin releasing hormone, tyrosine hydroxylase, and cytochrome oxidase reactivity within the hypothalamus of chicks showing early sexual maturation. Histochemistry. 99:1993;221-229.
20. Fraley G.S., Ulibarri C. The role of peripubertal gonadal steroids in the production of CGRPir in SNB motoneurons of Mongolian gerbils. Soc. Neurosci. Abstr. 21:1995;38.
21. G.S. Fraley, C. Ulibarri, Neonatal development of the spinal nucleus of the bulbocavernosus in the Mongolian gerbil: Delayed development during normal ontogeny, Dev. Brain Res. 1996 (in press).
22. Fraley G.S., Ulibarri C. Prepubertal but not adult castration alters the number of SNB motoneurons. Soc. Neurosci. Abstr. 23:1997;626.
23. Gon G.A., Giaid A., Steel J.H., et al. Localization of immunoreactivity for calcitonin gene-related peptide in the rat anterior pituitary during ontogeny and gonadal steroid manipulation and detection of its messenger ribonucleic acid. Endocrinology. 127:1990;2618-2626.
24. Hempstead B.L., Martin-Anca D., Kaplan D.r., Parada L.F., Chao M.V. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature. 350:1991;678-682.
25. Heuer J.G., Fatemie-Naine S., Wheeler E.F., Bothwell M. Structure and developmental expression of the chicken NGF receptor. Dev. Biol. 137:1990;287-304.
26. Heuer J.G., von Bartheld C.S., Kinoshita Y., Evers P.C., Bothwell M. Alternating phases of FGF receptor and NGF receptor expression in the developing chicken nervous system. Neuron. 5:1990;283-296.
27. trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF. Neuron. 9:1992;465-478.
28. Jordan C.L., Padgett B., Hershey J., Prins G., Arnold A. Ontogeny of androgen receptor immunoreactivity in lumbar motoneurons and in the sexually dimorphic levator ani muscle of male rats. J. Comp. Neurol. 379:1997;88-98.
29. Jung I., Baulieu E.E. Testosterone cytosol 'receptor' in the rat levator ani muscle. Nature New Biol. 237:1972;24-26.
30. Kiernan J.A., Hudson A.J. Changes in shapes of surviving motor neurons in amyotrophic lateral sclerosis. Brain. 116:1993;203-215.
31. Klein R., Smeyne R.J., Wurst W., et al. The trk proto-oncogene encodes a receptor for nerve growth factor. Cell. 65:1991;189-197.
32. Koliatsos V.E., Price D.L., Clatterbuck R.E. Motor neurons in Onuf's nucleus and its rat homologues express the p75 nerve growth factor receptor: sexual dimorphism and regulation by axotomy. J. Comp. Neurol. 345:1994;510-527.
33. Kramer B.M., Van der Zee C.E., Hagg T. p75 nerve growth factor receptor is important for retrograde transport of neurotrophins in adult cholinergic basal forebrain neurons. Neuroscience. 94:1999;1163-1172.
34. Helke C.J., Adryan K.M., Fedorowicz J., et al. Axonal transport of neurotrophins by visceral afferent and efferent neurons of the vagus nerve of the rat. J. Comp. Neurol. 393:1998;102-117.
35. Lee K.F., Li E., Huber J., et al. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 69:1992;737-749.
36. Lubischer J.L., Arnold A.P. Axotomy of developing rat spinal motoneurons: cell survival, soma size, muscle recovery, and the influence of testosterone. J. Neurobiol. 26:1995;225-240.
37. Mannen T., Iwata M., Tokoyura Y., Nagashima K. Preservation of certain motoneurone group of the sacral cord in amyotrophic lateral sclerosis: its clinical significance. J. Neurol. Neurosurg. Psychiatr. 40:1977;464-469.
38. Matsumoto A., Arai Y., Hyodo S. Androgenic regulation of expression of b-tubulin messenger ribonucleic acid in motoneurons of the spinal nucleus of the bulbocavernosus. J. Neuroendocrinol. 5:1994;357-363.
39. McKay S.E., Garner A., Caldero J., Tucker R.P., Oppenheim R.W. The expression of trkB and p75 and the role of BDNF in the developing neuromuscular system of the chick embryo. Development. 122:1996;715-724.
40. Meakin S.O., Shooter E.M. The nerve growth family of receptors. Trends Neurosci. 15:1992;323-331.
41. Nordeen E.J., Nordeen K.W., Sengelaub D.R., Arnold A.P. Androgens prevent normally occurring cell death in a sexually dimorphic spinal nucleus. Science. 229:1985;671-673.
42. Rabizadah S., Oh J., Zhong L.T., et al. Induction of apoptosis by the low-affinity NGF receptor. Science. 261:1993;345-348.
43. Radeke M.J., Feinstein S.C. Analytical purification of the slow, high affinity NGF receptor: Identification of a novel 135kd polypeptide. Neuron. 7:1991;141-150.
44. Rand M.K., Breedlove S.M. Androgen locally regulates rat bulbocavernosus and levator ani size. J. Neurobiol. 23:1992;17-30.
45. Sachs B.D. Role of the rat's striated penile muscles in penile reflexes, copulation, and the induction of pregnancy. J. Reprod. Fertil. 66:1982;433-443.
46. Sasaki S., Maruyama S. A fine structural study of Onuf's nucleus in sporadic amyotrophic lateral sclerosis. J. Neuro. Sci. 119:1993;28-37.
47. Schrøder H.D. Organization of the motoneurons innervating the pelvic muscles of the male rat. J. Comp. Neurol. 192:1980;567-587.
48. Sendtner M., Holtmann B., Kolbeck R., Thoenen H., Barde Y.A. Brain-derived neurotrophic factor and neurotrophin-3 prevent the death of motoneurons in newborn rats after nerve section. Nature. 360:1992;757-759.
49. Sengelaub D.R., Arnold A.P. Development and loss of early projections in a sexually dimorphic rat spinal nucleus. J. Neurosci. 6:1986;1613-1620.
50. Sengelaub D.R., Arnold A.P. Hormonal control of neuron number in sexually dimorphic spinal nuclei of the rat: I. testosterone-regulated death in dorsolateral nucleus. J. Comp. Neurol. 280:1989;622-629.
51. Sokal R.R., Rohlf F.J., Introduction to Biostatistics. 2nd Edition: 1987;W.H. Freeman and Co, New York, NY.
52. Strahle U., Boshart M., Klock G., Stewart F., Schutz G. Glucocorticoid and progesterone specific effects are determined by differential expression of the respective hormone receptors. Science. 339:1989;629-632.
53. Tirassa P., Thiblin I., Agren G., Vigneti E., Aloe L., Stenfors C. High-dose anabolic androgenic steroids modulate concentrations of nerve growth factor and expression of its low affinity receptor (p75-NGFr) in male rat brain. J. Neurosci. Res. 47:1997;198-207.
54. Tonra J.R., Mendell L.M. Effects of postnatal anti-NGF on the development of CGRP-ir neurons in the dorsal root ganglion. J. Comp. Neurol. 392:1998;489-498.
55. C. Ulibarri, G.S. Fraley, Effects of prepubertal castration and adult hormonal replacement, Soc. Neurosci. Abstr. 23 (1997) 251.2.
56. Ulibarri C., Popper P., Micevych P.C. Motoneurons dorsolateral to the central canal innervate perineal muscles in the Mongolian gerbil. J. Comp. Neurol. 356:1995;225-237.
57. von Bartheld C.S., Williams R., Lefcort F., Clary D.G. Retrograde transport of neurotrophins from the eye to the brain in chick embryos: roles of the p75NTR and trkB receptors. J. Neurosci. 16:1996;2995-3008.
58. Vercelli A., Cracco C. Effects of prepubertal castration on the spinal motor nucleus of the ischiocavernosus muscle of the rat. Cell Tiss. Res. 262:1990;551-557.
59. Verge V.M.K., Merlio J.P., Grondin J., et al. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF. J. Neurosci. 12:1992;4011-4022.
60. Wainman P., Shipounoff G.C. The effects of castration and testosterone propionate on the striated perineal musculature in the rat. Endocrinology. 29:1941;975-978.
61. Wee B.E.F., Clemens L.G. Characteristics of the spinal nucleus of the bulbocavernosus are influenced by genotype in the house mouse. Brain Res. 424:1987;305-310.
62. Yan Q., Johnson E.M. An immunohistochemical study of the nerve growth factor receptor in developing rats. J. Neurosci. 8:1988;3481-3498.
63. Yan Q., Elliot J.L., Snider W.D. Brain-derived neurotrophic factor rescues spinal cord motor neurons from axotomy-induced cell death. Nature. 360:1992;753-755.
64. Yarbrough W.G., Quarmby V.E., Simental J.A., et al. A single base mutation in the androgen receptor gene causes androgen insensitivity in the testicular feminized rat. J. Biol. Chem. 265:1990;8893-8900.