Mouse model for atherosclerotic plaque rupture

Circulation

Volumn 105, Issue 17, 2002, Pages 2010-2011

  Majesky, Mark W ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Apolipoproteins; Apoptosis; Editorials; Fibrin; Plaque

Indexed keywords

APOLIPOPROTEIN E; PHENYLEPHRINE; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ATHEROSCLEROTIC PLAQUE; EDITORIAL; EXPERIMENTAL ANIMAL; GENE OVEREXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RUPTURE; SMOOTH MUSCLE; THROMBUS;

ADENOVIRIDAE; ANIMALS; APOLIPOPROTEINS E; APOPTOSIS; ARTERIOSCLEROSIS; DISEASE MODELS, ANIMAL; FORECASTING; GENETIC VECTORS; HUMANS; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037197739     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000016964.88228.E0     Document Type: Editorial

References (12)

1. -/- mice following adenovirus-mediated transfer of p53
2. The thin-cap fibroatheroma: A type of vulnerable plaque. The major precursor lesion to acute coronary syndromes
3. Atherosclerotic plaque rupture in the apolipoprotein E knockout mouse
4. Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse
5. Aortic atherosclerotic plaque injury in apolipoprotein E deficient mice
6. Increased sensitivity of human vascular smooth muscle cells from atherosclerotic plaques to p53-mediated apoptosis
7. Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice
8. Current concepts of the pathogenesis of the acute coronary syndromes
9. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice
10. The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo
11. Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE*3-Leiden transgenic mice
12. α1-adrenergic stimulation of platelet-derived growth factor A-chain gene expression in rat aorta