HIV-1: Hitching a ride on erythrocytes

Lancet

Volumn 359, Issue 9325, 2002, Pages 2212-2213

  Levy, Jay A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; VIRUS RNA;

DRUG MECHANISM; ERYTHROCYTE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; NOTE; PRIORITY JOURNAL; TARGET CELL; VIROGENESIS; VIRUS DETECTION; VIRUS REPLICATION;

EID: 0037193840     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(02)09314-5     Document Type: Note

References (18)

1. Circulating immune complexes in patients with acquired immune deficiency syndrome contain the AIDS-associated retrovirus
2. Follicular dendritic cells are a major reservoir for human immunodeficiency virus type 1 in lymphoid tissues facilitating infection of CD4+ T-helper cells
3. Follicular dendritic cells and human immunodeficiency virus infectivity
4. Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells
5. DC-SIGN interactions with human immunodeficiency virus: Virus binding and transfer are dissociable functions
6. Immune complexes containing human immunodeficiency virus type 1 primary isolates bind to lymphoid tissue B lymphocytes and are infectious for T lymphocytes
7. CD4-negative cells bind human immunodeficiency virus type 1 and efficiently transfer virus to T cells
8. B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells
9. Efficient virus transmission from dendritic cells to CD4+ T cells in response to antigen depends on close contact through adhesion molecules
10. Dendritic cells transmit human immunodeficiency virus type 1 to monocytes and monocyte-derived macrophages
11. The human immuno-deficiency virus can infect CD4-negative human fibroblastoid cells
12. Increased infectivity of HIV type 1 particles bound to cell surface and solid-phase ICAM-1 and VCAM-1 through acquired adhesion molecules LFA-1 and VLA-4
13. Human immunodeficiency virus (HIV)-infected cells and free virus directly activate the classical complement pathway in rabbit, mouse and guinea-pig sera; Activation results in virus neutralization by virolysis
14. Interaction of non-antibody factors with HIV in plasma
15. Detection of plasma viremia in HIV-infected individuals at all clinical stages
16. Ultrastructural characterization of the interaction of bluetongue virus with bovine erythrocytes in vitro
17. Caution: Should we be treating HIV infection early?