Mono N-arylation of piperazine(III): Metal-catalyzed N-arylation and its application to the novel preparations of the antifungal posaconazole and its advanced intermediate

Tetrahedron Letters

Volumn 43, Issue 18, 2002, Pages 3359-3363

  Hepperle, Michael ^a   Eckert, Jeffrey ^a   Gala, Dinesh ^a   Shen, Lan ^a   Anderson Evans, C ^a   Goodman, Andrew ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; N (4 HYDROXYPHENYL) N' (4 AMINOPHENYL)PIPERAZINE; PALLADIUM; PIPERAZINE DERIVATIVE; POSACONAZOLE; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CATALYSIS; CATALYST; CHEMICAL REACTION; DEMETHYLATION; DRUG SYNTHESIS; HYDROGENATION;

EID: 0037193130     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)00556-7     Document Type: Article

References (21)