Long-term culture of islets abrogates cytokine-induced or lymphocyte-induced increase of antigen expression on β cells

Transplantation

Volumn 74, Issue 4, 2002, Pages 440-445

  Kuttler, B ^a   Hartmann, A ^a   Wanka, H ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN; RECOMBINANT INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL CULTURE; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MIXED LYMPHOCYTE CULTURE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0037183639     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200208270-00003     Document Type: Article

References (42)

1. Induction of Ia in rat pancreas allografts: The effect of donor specific blood transfusion pretreatment or Cyclosporin A
2. Class II alloantigen induced on corneal endothelium, role in corneal allograft rejection
3. Induction of vascular adhesion molecules during rejection of human cardiac allografts
4. Induction of class II major histocompatibility antigens on thyroid, adult pancreatic islet, and fetal proislet allografts
5. Optic nerve degeneration induces the expression of MHC antigens in the rat visual system
6. Acute kidney graft rejection. a morphological and immunohistological study on "zero-hour" and follow-up biopsies with special emphasis on cellular infiltrates and adhesion molecules
7. Induction of adhesion molecules on the endothelia of rejecting cardiac allografts
8. Survival and MHC-expression of embryonic retinal transplants in the choroids
9. MHC expression in syngeneic and allogeneic retinal cell transplants in the rat
10. Synergistic interactions of CD4+ and CD8+ T cell subsets with human vascular endothelial cells in primary proliferative allogeneic responses
11. Interacting monocytes and synoviocytes induce adhesion molecules by a cytokine-regulated process
12. Co-culture of pancreatic islets and allogeneic lymphocytes: Alterations of responder and stimulator cells
13. Tissue culture reduces Ia-bearing cells in rat islets and prolongs islet allograft survival
14. Depletion of donor Ia+ cells before transplantation does not prolong allograft survival
15. Allotransplantation of culture-isolated neonatal rat islet tissue. Absence of MHC class II positive antigen-presenting cells in nonimmunogenic islets
16. Reversal of diabetes in nude mice after transplantation of fresh and 7-day-cultured (24°C) human pancreatic islets
17. Results of our first nine intraportal islet allografts in type 1, insulin-dependent diabetic patients
18. Modulation of MHC class I antigen decreases pancreatic islet immunogenicity
19. Indefinite survival of MHC class I-deficient murine pancreatic islet allografts
20. Major histocompatibility complex I deficiency prolongs islet allograft survival
21. Prolongation of in vivo mouse islet allograft survival by modulation of MHC class I antigen
22. Transplanted MHC class I-deficient nonobese mouse islets are protected from autoimmune injury in diabetic nonobese recipients
23. Elimination of IA-bearing cells by in vitro isolation and culture of neonatal rat pancreatic islets
24. MHC class II antigen expression on the various cells of normal and activated isolated pancreatic islets
25. The use of ultraviolet irradiation of islets and cyclosporine in facilitating indefinite pancreatic allograft acceptance
26. Pretreatment of rat pancreatic islets with MHC I-A monoclonal antibody: In-vitro and in-vivo effects on islet antigenicity
27. The effect of islet cell culture in vitro at 24 degrees C on graft survival and MHC antigen expression
28. Unexpected effects of cryopreservation on antigen expression of pancreatic beta-cells
29. Heat shock reduces antigen expression on islet cells
30. The use of a new dextran gradient medium for rapid isolation of functionally intact neonatal rat pancreatic islets
31. Phenotyping of lymphocytes following transplantation of allogeneic rat pancreatic islets into streptozotocin-diabetic recipients
32. Preparation of suspensions of pancreatic islet cells: A comparison of methods
33. Monoclonal antibody-mediated cytotoxicity against beta cells detected in vitro does not cause beta-cell destruction in vivo
34. Islet transplantation in seven patients with type I diabetes mellitus using a glucocorticoid free immunosuppressive regimen
35. Prevention of rejection of murine islet allografts by pre-treatment with anti-dendritic cell antibody
36. Long-term survival of rat islet allografts after pre-treatment with low dose gamma irradiation
37. Endothelial cells in pancreatic islets and the effect of culture
38. Endothelial cells as antigen-presenting cells: Role in human transplant rejection
39. Immunobiology of human vascular endothelium
40. Antigen presentation by murine endothelial cells
41. Biosynthesis and metabolism of endothelium-derived nitric oxide
42. Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1 beta and IFN-gamma