Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome

Neurology

Volumn 59, Issue 4, 2002, Pages 639-641

  Allen, R P ^a   Mignot, E ^a   Ripley, B ^a   Nishino, S ^a   Earley, C J ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OREXIN A;

ADULT; ARTICLE; CEREBROSPINAL FLUID EXAMINATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; ONSET AGE; PRIORITY JOURNAL; PROTEIN TRANSPORT; RESTLESS LEGS SYNDROME; SLEEP DISORDER;

EID: 0037183509     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.59.4.639     Document Type: Article

References (10)

1. Restless legs syndrome: A review of clinical and pathophysiologic features
2. The role of hypocretins (orexins) in sleep regulation and narcolepsy
3. Immobilization tests and periodic leg movements in sleep for the diagnosis of restless leg syndrome
4. Validation of the Johns Hopkins Restless Legs Severity Scale (JHRLSS)
5. Evaluation of the PAM-RL system for the detection of periodic leg movements during sleep in the lab and home environments
6. CSF hypocretin/orexin levels in narcolepsy and other neurological conditions
7. Diurnal variation of CSF hypocretin-1 (orexin A) levels in control and depressed subjects
8. Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities
9. Hypocretin/orexin release in normal and narcoleptic dogs: Comparison of the effects of food deprivation, eating, sleep deprivation and motor activity
10. Normal hypocretin-1 levels in Parkinson's disease patients with excessive daytime sleepiness