Activation of CFTR Cl- channel by tyrphostins via a protein tyrosine kinase-independent pathway in forskolin-stimulated renal epithelial A6 cells

Life Sciences

Volumn 71, Issue 10, 2002, Pages 1199-1207

  Niisato, Naomi ^a   Nishio, Kyosuke ^a,b   Marunaka, Yoshinori ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Shin Koiwa Clinic   (Japan)

Author keywords

cAMP; Cl channel; Cl secretion; NPPB; Protein tyrosine kinase; Tyrphostin A23; Tyrphostin A63

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; BENZAMIL; CHLORIDE CHANNEL; CHLORIDE ION; CYCLIC AMP; FORSKOLIN; PROTEIN TYROSINE KINASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; TYRPHOSTIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CHLORIDE TRANSPORT; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; EPITHELIUM CELL; KIDNEY EPITHELIUM; NONHUMAN; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STIMULATION;

AMILORIDE; ANIMALS; CELLS, CULTURED; CHLORIDE CHANNELS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME INHIBITORS; EPITHELIAL CELLS; FORSKOLIN; KIDNEY; KINETICS; NITROBENZOATES; PATCH-CLAMP TECHNIQUES; PROTEIN-TYROSINE KINASES; TEMPERATURE; TYRPHOSTINS;

EID: 0037178595     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01824-6     Document Type: Article

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