Interspecific neisserial high molecular weight proteins able to induce natural immunity responses are strongly correlated with in vitro bactericidal activity

Vaccine

Volumn 20, Issue 23-24, 2002, Pages 2964-2971

  Sánchez, Sandra ^a   Troncoso, Gemma ^a   Criado, Ma Teresa ^a   Ferreirós, Carlos ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Bactericidal activity; Cross reactive antigens; Neisseria meningitidis

Indexed keywords

BACTERIAL PROTEIN; MENINGOCOCCUS VACCINE; OUTER MEMBRANE PROTEIN; BACTERIAL ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS REACTION; DRUG FORMULATION; IMMUNITY; IMMUNOGENICITY; IN VIVO STUDY; MENINGITIS; MICROBIAL ACTIVITY; MOUSE; NEISSERIA; NEISSERIA LACTAMICA; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; EPIDEMIC MENINGITIS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; MOLECULAR WEIGHT; SERUM BACTERICIDAL ACTIVITY; SPECIES DIFFERENCE;

ANIMAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BLOOD BACTERICIDAL ACTIVITY; CROSS REACTIONS; HUMAN; IMMUNITY, NATURAL; MENINGITIS, MENINGOCOCCAL; MENINGOCOCCAL VACCINES; MICE; MICE, INBRED BALB C; MOLECULAR WEIGHT; NEISSERIA; NEISSERIA MENINGITIDIS; SPECIES SPECIFICITY; SUPPORT, NON-U.S. GOV'T; ANIMALS; HUMANS;

EID: 0037178309     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00221-9     Document Type: Article

References (23)

1. Meningococcal vaccines: Current status and future possibilities
2. Meningococcal vaccines: Past, present and future
3. Vaccines for prevention of meningococcal disease
4. Immunologycal response in man to group B meningococal polysaccharide vaccines
5. Dynamics of the murine humoral immune response to Neisseria meningitidis group B capsular polysaccharide
6. Antibodies to polysialic acid and its N-propyl derivative: Binding properties and interaction with human embryonal brain glycopeptides
7. Capsular switching of Neisseria meningitidis
8. Phase and antigenic variation-the impact on strategies for bacterial vaccine design
9. Bacterial antigenic variation, host immune response, and pathogenic-host coevolution
10. Molecular switches-the on and off of bacterial phase variation
11. Antigenic cross-reactivity between outer membrane proteins of Neisseria meningitidis and Neisseria species
12. Evaluation of cross-reactive antigens as determinants of cross-bactericidal activity in pathogenic and commensal Neisseria
13. Blocking of iron uptake from transferrin by antibodies against the transferin binding proteins in N. meningitidis
14. Bactericidad activity of antibodies elicited against the Neisseria meningitidis 37 kDa ferric binding protein (FbpA) with different adjuvants
15. Measurement of protein using bicinchonic acid
16. Protection against infection with N. meningitidis group B serotype 2b by passive immunisation with serotype-specific monoclonal anti-body
17. Studies of the mechanisms of bacterial resistance to complement-mediated killing. Part IV. C5b-9 forms high molecular weight complexes with bacterial outer membrane constituents on serum resistant but not serum-sensitive Neisseria gonorrhoeae
18. Complement mediated bactericidal activity of human antibodies to polya2→8 N-acetylneuraminic acid, the capsular polysaccharide of Neisseria meningitidis serogroup B
19. Solid-phase screening of monoclonal antibodies
20. Copper staining: A five-minute protein stain for sodium dodecyl sulfate polyacrylamide gels
21. Serum bactericidal activity in a secondary school population following an outbreak of meningococcal disease: Effects of carriage and secretor status
22. Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
23. Identification and characterisation of App: An immunogenic autotransporter protein of Neisseria meningitidis