Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1

Biochemistry

Volumn 41, Issue 25, 2002, Pages 8075-8081

  Reyes, Alejandro M ^a   Bustamante, Fernando ^a   Rivas, Coralia I ^b   Ortega, Marcela ^a   Donnet, Claudia ^c   Rossi, Juan P ^c   Fischbarg, Jorge ^d   Vera, Juan Carlos ^b  

^a UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^b UNIVERSITY OF CONCEPCIÓN   (Chile)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^d Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE;

CELL MEMBRANES; GLUCOSE; PROTEINS; VITAMINS;

BIOCHEMISTRY;

CYTOCHALASIN B; GENISTEIN; GLUCOSE TRANSPORTER 1; MYRICETIN; NICOTINAMIDE;

ARTICLE; CELL MEMBRANE TRANSPORT; CHO CELL; CONTROLLED STUDY; ENZYME SUBSTRATE; ERYTHROCYTE MEMBRANE; GENETIC TRANSFECTION; HEXOSE TRANSPORT; HUMAN; HUMAN CELL; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION;

3-O-METHYLGLUCOSE; ANIMALS; CHO CELLS; CRICETINAE; CYTOCHALASIN B; DEOXYGLUCOSE; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; FLAVONOIDS; GENISTEIN; GLUCOSE TRANSPORTER TYPE 1; HUMANS; MONOSACCHARIDE TRANSPORT PROTEINS; NIACINAMIDE; PROTEIN BINDING; TRANSFECTION; TRANSPORT VESICLES;

EID: 0037172788     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0256328     Document Type: Article

References (41)

1. Facilitated diffusion of glucose
2. Facilitative glucose transporters
3. Sequence and structure of a human glucose transporter
4. Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein
5. Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells
6. Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues
7. Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues
8. Identification of a novel gene encoding an insulin-responsive glucose transporter protein
9. Characterization and expression of human HepG2/erythrocyte glucose-transporter gene
10. Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6)
11. Cloning and expression of a hepatic microsomal glucose transport protein. Comparison with liver plasma-membrane glucose-transport protein GLUT 2
12. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues
13. Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9)
14. The extended GLUT-family of sugar/polyol transport facilitators: Nomenclature, sequence characteristics, and potential function of its novel members
15. Homeostasis without a GLUT
16. Liver glucose transporter: A basolateral protein in hepatocytes and intestine and kidney cells
17. Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5
18. Hexose transporter expression and function in mammalian spermatozoa: Cellular localization and transport of hexoses and vitamin C
19. Fructose transporter in human spermatozoa and small intestine is GLUT5
20. Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes
21. Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle
22. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid
23. Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid
24. Evidence that the glucose transporter serves as a water channel in J774 macrophages
25. Glucose transporters serve as water channels
26. Interaction of benzoic acid derivatives with the transport system of glucose in human erythrocytes
27. Interaction of steroids with the transport system of glucose in human erythrocytes
28. Barbiturates inhibit hexose transport in cultured mammalian cells and human erythrocytes and interact directly with purified GLUT-1
29. Direct inhibition of the hexose transporter GLUT1 by tyrosine kinase inhibitors
30. Possible multifunction of glucose transporter. Transport of nicotinamide by reconstituted liposomes
31. Specific binding and uptake of extracellular nicotinamide in human leukemic K-562 cells
32. Genistein is a natural inhibitor of hexose and dehydroascorbic acid transport through the glucose transporter, GLUT1
33. Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes
34. Inhibition by nucleosides of glucose-transport activity in human erythrocytes
35. Asymmetry of the hexose transfer system in human erythrocytes. Comparison of the effects of cytochalasin B, phloretin and maltose as competitive inhibitors
36. Inhibitions of sugar transport produced by ligands binding at opposite sides of the membrane. Evidence for simultaneous occupation of the carrier by maltose and cytochalasin B
37. The human erythrocyte sugar transporter presents two sugar import sites
38. Monosaccharide transporter of the human erythrocyte. Characterization of an improved preparation
39. Cholate-solubilized erythrocyte glucose transporters exist as a mixture of homodimers and homotetramers
40. Purification and characterization of human erythrocyte glucose transporter in decylmaltoside detergent solution