Frequent loss of heterozygosity in chromosomal region 9pter-p13 in tumor biopsies and cytological material of uterine cervical cancer

Cancer Letters

Volumn 176, Issue 2, 2002, Pages 175-181

  Manolaraki, Maria M ^a   Arvanitis, Demetrios A ^a   Sourvinos, George ^a   Sifakis, Stavros ^a   Koumantakis, Eugenios ^a   Spandidos, Demetrios A ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

9pter p13; Cervical cancer; Cytological material; Loss of heterozygosity; Microsatellite analysis

Indexed keywords

ACCURACY; ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CHROMOSOME 9P; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLOGY; EARLY DIAGNOSIS; FEMALE; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MICROSATELLITE INSTABILITY; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA;

ADULT; AGED; ALLELES; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; GENOTYPE; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MIDDLE AGED; MODELS, GENETIC; PHENOTYPE; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS, DNA; UTERINE CERVICAL NEOPLASMS;

EID: 0037169863     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00750-9     Document Type: Article

References (26)

1. Cancer of the uterine cervix
2. Papillomaviruses causing cancer: Evasion from host-cell control in early events in carcinogenesis
3. Microsatellite instability: Marker of mutator phenotype in cancer
4. Toward fully automated genotyping: Genotyping microsatellite markers by deconvolution
5. The molecular genetics of cervical carcinoma
6. Molecular events in uterine cervical cancer
7. Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2
8. Evidence for two candidate tumour suppressor loci on chromosome 9q in transitional cell carcinoma (TCC) of the bladder but no homozygous deletions in bladder tumour cell lines
9. Loss of heterozygocity on chromosome 8 in squamous cell carcinomas of the head and neck
10. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome
11. Sensitivity and limitations of high throughput fluorescent microsatellite analysis for the detection of allelic imbalance: Application in lung tumours
12. Cancer epigenetics comes of age
13. Genomic alterations in cervical carcinoma: Losses of chromosome heterozygosity and human papilloma virus tumor status
14. Different profiles of allelic losses in cervical carcinoma cases in Surinam and The Netherlands
15. Allelic loss on chromosome 1 is associated with tumor progression of cervical carcinoma
16. Microsatellite instability is a late event in the carcinogenesis of uterine cervical cancer
17. Frequent loss of heterozygosity of chromosome 3 short arm detected by PCR-based microsatellite polymorphisms in cervical squamous cell carcinoma
18. Microsatellite instability in cervical intraepithelial neoplasia
19. Microsatellite alterations in bronchial and sputum specimens of lung cancer patients
20. Genetic alterations in bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer
21. Genetic detection of bladder cancer by microsatellite analysis of p16, RB1, and p53 tumor suppressor genes
22. Molecular detection of primary bladder cancer by Microsatellite analysis
23. Microsatellite alterations as clonal markers for the detection of human cancer
24. Low incidence of Microsatellite instability in patients with cervical carcinomas
25. Monoclonality and surface Lesion-specific microsatellite alterations in premalignant and malignant neoplasia of uterine cervix: A local field effect of genomic instability and clonal evolution